Clinical trials · Philadelphia, PA
Heart Failure With Reduced Ejection Fraction clinical trials in Philadelphia
We’re tracking 9 recruiting heart failure with reduced ejection fraction studies with a site in or near Philadelphia — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT06736574RecruitingPhase 3
Study of omecamtiv mecarbil for chronic heart failure with very weak heart pump
This study tests an investigational medicine (omecamtiv mecarbil) for people with chronic heart failure and very low pumping strength. It looks at whether the drug can help prevent heart failure events or the need for stronger treatments.
Philadelphia, PennsylvaniaAges 18–85 - NCT06552637Recruiting
Diaphragm stimulation for heart failure
This trial tests a device that stimulates your diaphragm (the muscle that helps you breathe) while you have heart failure. It may help improve your breathing and heart function. The study is for people with moderate heart failure symptoms whose heart pumps less blood than normal.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05650658Recruiting
Compare two heart pacing options in people with weak heart function
This trial compares two types of “left-side” heart pacing to see which one works better in people with weak heart pumping. It may help guide the best pacing choice for improving heart function and symptoms.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06008197RecruitingPhase 3
A study of finerenone for hospitalized heart failure patients
This trial tests a medication called finerenone to see if it helps people hospitalized for heart failure live longer and have fewer heart-related problems. It may be an option for those with a certain type of heart failure where the heart's pumping strength is mildly reduced or normal.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05138575RecruitingPhase 2
Testing SGLT2 pill and potassium nitrate for heart failure with preserved EF
This trial studies whether two medicines—an SGLT2 inhibitor and potassium nitrate—can improve symptoms and heart function in people with heart failure with preserved ejection fraction (HFpEF). It focuses on people who still have signs of “stiff” or high filling pressure in the heart despite a normal-ish ejection fraction.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04913805RecruitingPhase 2
Study for HFpEF using heart pressure and energy signals
This Phase 2 study tests how matching heart “filling pressure” and heart muscle “energy use” may improve understanding or treatment of HFpEF, a type of heart failure with preserved pumping strength. You may be asked to have heart scans/tests and follow a study plan if your symptoms and test results fit.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07037459RecruitingPhase 3
A study of a new drug for heart failure with obesity
This trial tests a medication called maridebart cafraglutide for people with heart failure (where the heart doesn't pump as well as it should) and obesity. The goal is to see if it can help improve symptoms and outcomes.
Marlton, New JerseyAges 18–99 - NCT07209098Recruiting
Heart failure study testing CCM therapy
This study tests a therapy called Cardiac Contractility Modulation (CCM) for people with heart failure. It uses a device to help the heart pump more strongly, and researchers compare it to standard care using patient records.
Marlton, New JerseyAges 18 years+
Hear when a new Heart Failure With Reduced Ejection Fraction trial opens near Philadelphia, PA
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Heart Failure With Reduced Ejection Fraction trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting heart failure with reduced ejection fraction studies listed above.
- University of Pennsylvania · 6 studies
- Virtua Health · 3 studies
- Thomas Jefferson University Hospital · 2 studies
- Abington Medical Specialists
- AtlantiCare Regional Medical Center
- Camden, NJ Investigative Site 10033
- Cooper University Hospital - Heart House
- Impulse Dynamics
What taking part in a heart failure with reduced ejection fraction study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting heart failure with reduced ejection fraction studies in Pennsylvania.
Common questions
- Are there heart failure with reduced ejection fraction clinical trials near Philadelphia?
- Yes. We're currently tracking 9 recruiting heart failure with reduced ejection fraction studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a heart failure with reduced ejection fraction study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a heart failure with reduced ejection fraction trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New heart failure with reduced ejection fraction studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.