Clinical trials · Minnesota
Heart failure clinical trials in Minnesota
We’re tracking 59 recruiting heart failure studies with a site in Minnesota — including Early Phase 1, Phase 1/Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Minnesota
- NCT06507657RecruitingEarly Phase 1
Empagliflozin for heart health in older adults
This study tests whether a medication called empagliflozin (a diabetes drug) can improve heart function in older adults with high blood pressure and obesity who are at risk for heart failure but do not have it yet. You would take the pill daily and have heart ultrasounds to check your heart's health.
Minneapolis, MinnesotaAges 60 years+ - NCT06195059Recruiting
Heart ultrasound with contrast during exercise to study lungs
This study uses a special ultrasound (echocardiography) with a contrast dye to see how blood flows through your lungs during exercise. It aims to help doctors better understand why patients get short of breath during activity.
Rochester, MinnesotaAges 18 years+ - NCT06039176Recruiting
Learning from the HeartMate 3 device
This study looks at information from the HeartMate 3 LVAD device to learn more about how it works and what it can tell us about the future. It may help people with advanced heart failure who need this specific device.
Rochester, MinnesotaAges 18–100 - NCT05685303Recruiting
Testing a treatment for heart failure symptoms with normal pumping ability
This study is looking at a new treatment for people with heart failure where the heart’s pumping strength is not reduced much (HFpEF or HFmrEF), but pressure inside the heart is high during exercise. It may help relieve symptoms in people who still feel unwell during normal activity despite stable standard treatment.
Minneapolis, MinnesotaAges 40 years+ - NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients
This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.
Rochester, MinnesotaAges 18 years+ - NCT05279742Enrolling by invitationPhase 1/Phase 2
Study drug to boost a hormone system in HFpEF
This early-phase trial tests a treatment that aims to improve the “natriuretic peptide” hormone system in people with HFpEF (heart failure with preserved pumping strength). It may help reduce symptoms and improve heart and fluid pressure behavior, especially in certain related conditions like kidney disease.
Rochester, MinnesotaAges 18 years+ - NCT05180773RecruitingPhase 4
Bromocriptine for new postpartum heart weakness
This trial studies whether bromocriptine improves health outcomes in people recently diagnosed with peripartum cardiomyopathy (a weakened heart during late pregnancy or soon after delivery). You may be asked about timing after childbirth, heart strength tests, and whether you plan to keep breastfeeding.
Rochester, MinnesotaAges 18 years+ - NCT04984473Recruiting
Breathing muscle training during heart rehab
This study tests whether breathing muscle training, added to regular heart rehab, can improve how well people with heart failure do day-to-day. It also compares results with healthy volunteers who do not have certain health problems.
Rochester, MinnesotaAges 18 years+ - NCT04592445Recruiting
Nerve ablation for right-sided symptoms in HFpEF heart failure
This trial tests a procedure to “turn off” the right greater splanchnic nerve to improve symptoms in people with HFpEF (heart failure with preserved pumping function). If successful, it may reduce shortness of breath and fluid congestion in daily life.
Rochester, MinnesotaAges 40 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Minneapolis, MinnesotaAges birth–20 years - NCT00271180Recruiting
Tracks long-term performance of Medtronic heart devices
This study follows how well certain Medtronic heart devices work over the long term. You may be included if you have a qualifying Medtronic implant and the research team can reliably get your implant and follow-up information.
Coon Rapids, MinnesotaAges Any age
Heart failure trials by city in Minnesota
Where these studies are running in Minnesota
Institutions with a site for the recruiting heart failure studies listed above.
- Mayo Clinic · 6 studies
- University of Minnesota · 3 studies
- Minneapolis Heart Institute Foundation · 2 studies
- Mayo Clinic-Rochester
What taking part in a heart failure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Heart failure trials in other states
Common questions
- Are there heart failure clinical trials in Minnesota?
- Yes. We're currently tracking 59 recruiting heart failure studies with a site in Minnesota, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a heart failure study in Minnesota?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Minnesota to take part?
- Not necessarily. These studies have a site in Minnesota, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New heart failure studies open in Minnesota regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.