Clinical trials · Miami, FL
High Grade Glioma clinical trials in Miami
We’re tracking 10 recruiting high grade glioma studies with a site in or near Miami — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Miami
- NCT06161974RecruitingPhase 2
Olutasidenib and temozolomide for IDH1-mutant high-grade glioma
This trial tests a combination of two oral medications, olutasidenib and temozolomide, for people with a specific type of aggressive brain tumor (high-grade glioma) that has an IDH1 mutation. The goal is to see if this combination can help control the tumor after standard treatment like radiation.
Miami, FloridaAges 12–39 - NCT04299191RecruitingPhase 1/Phase 2
LAM561 for children with advanced brain or solid tumors
This Phase 1/2 study tests a medicine called LAM561 in children whose cancer is advanced and not responding to standard treatment. The goal is to see if the drug is safe and can shrink or control tumors in this setting.
Miami, FloridaAges Up to 18 years - NCT06504381RecruitingPhase 1/Phase 2
DB107 and radiation therapy for high-grade glioma
This trial tests a new two-part treatment (DB107-RRV and DB107-FC) combined with radiation, with or without the chemotherapy drug temozolomide, for people with newly diagnosed high-grade glioma. It aims to see if this approach is safe and effective.
Miami, FloridaAges 18 years+ - NCT05099003RecruitingPhase 1/Phase 2
Selinexor plus radiation for newly diagnosed brain tumors
This trial studies whether adding selinexor to standard radiation can improve outcomes for children and young teens with certain newly diagnosed high-grade brain tumors (including DIPG). It’s designed for specific tumor types and genetic markers, and people must be able to start treatment soon after diagnosis.
Miami, FloridaAges 1–21 - NCT06838676RecruitingPhase 2
ACT001 for DIPG and H3K27-altered high-grade gliomas
This trial tests a drug called ACT001 for people with diffuse intrinsic pontine glioma (DIPG) or certain high-grade gliomas that have a specific genetic change (H3K27-altered). It includes two groups: one for newly diagnosed DIPG after radiation, and another for progressive or recurrent disease.
Miami, FloridaAges 1–39 - NCT06428045RecruitingPhase 1
STARLITE for hard-to-surgery high-grade brain tumors
This trial tests a new treatment called STARLITE for people with fast-growing brain tumors (high-grade gliomas) that cannot be safely removed with surgery. The treatment uses a laser to destroy the tumor from the inside. It may be a good option if you haven't had any prior treatment for this tumor.
Miami, FloridaAges 18 years+ - NCT06860594RecruitingPhase 1
Triapine plus radiation for recurrent brain tumors
This trial tests whether adding an experimental drug called triapine to a second round of radiation therapy can help treat brain tumors that have come back after initial treatment. It may be a good option for people with recurrent glioblastoma or astrocytoma who meet safety criteria.
Miami, FloridaAges 18 years+ - NCT05096481RecruitingPhase 2
Vaccine trial for children with certain brain tumors
This Phase 2 study tests a vaccine made to target CMV (a virus) in order to treat children with medulloblastoma or newly diagnosed high-grade glioma/DIPG. If you’re eligible, you’d receive the study vaccine and the team would closely watch how well it’s tolerated and how your cancer responds.
Miami, FloridaAges 3–39 - NCT05303519RecruitingPhase 3
Safusidenib for IDH1-mutant glioma after main treatment
This Phase 3 trial tests safusidenib, a targeted medicine, to help stop or slow the return of certain brain tumors with an IDH1 mutation. It focuses on people after initial treatment (surgery and/or radiation and temozolomide), aiming to improve outcomes during maintenance therapy.
Miami, FloridaAges 18 years+ - NCT06264388RecruitingPhase 2
Gene therapy plus oral drug for recurrent brain tumors
This trial tests a two-part treatment: an injected virus (DB107-RRV) plus an oral medication (DB107-FC) for people whose high-grade glioma (a type of brain tumor) has come back. The virus is designed to deliver a gene that makes the tumor sensitive to the oral drug, which then helps kill the cancer cells.
Miami, FloridaAges 18–75
Hear when a new High Grade Glioma trial opens near Miami, FL
We’ll email you when one opens near Miami, FL — at most once a week, no account needed, unsubscribe anytime.
High Grade Glioma trials in other cities
Where these studies are running near Miami
Institutions with a site for the recruiting high grade glioma studies listed above.
- University of Miami · 8 studies
- Nicklaus Children's Hospital · 2 studies
- Miami Cancer Institute
- Sylvester Comprehensive Cancer Center at Hollywood
- Sylvester Comprehensive Cancer Center at Plantation
- UM Sylvester Comprehensive Cancer Center at Coral Gables
- UM Sylvester Comprehensive Cancer Center at Coral Springs
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach
What taking part in a high grade glioma study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting high grade glioma studies in Florida.
Common questions
- Are there high grade glioma clinical trials near Miami?
- Yes. We're currently tracking 10 recruiting high grade glioma studies with a site near Miami, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high grade glioma study near Miami?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Miami to take part?
- Not necessarily. These studies have a site near Miami, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high grade glioma trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high grade glioma studies open near Miami regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.