Clinical trials
HoLEP clinical trials
Below are recruiting holep clinical trials, each written for real people, not researchers. We’re tracking 22 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07631286Recruiting
Prostate surgery technique to preserve ejaculation function
This study compares two surgical approaches for removing prostate tissue to relieve urinary symptoms. The experimental approach is designed to help men maintain normal ejaculation after surgery, while the standard approach may affect this function.
Chicago, IllinoisAges 18–100 - NCT06975033Recruiting
Video discharge instructions after prostate surgery
This study tests if watching a short educational video before going home after HoLEP prostate surgery helps patients understand their recovery better. The goal is to see if the video reduces questions or visits to the doctor after surgery.
San Francisco, CaliforniaAges 18 years+ - NCT07741656Recruiting
A study of the Beacon platform for laser prostate surgery
This trial tests a new tool (the Beacon Platform) that helps doctors perform a type of laser surgery for an enlarged prostate, called HoLEP. The goal is to see if it makes the surgery easier and more effective, which could help you urinate better.
SofiaAges 45 years+ - NCT07741214Enrolling by invitation
Low-power prostate surgery comparison
This trial compares two common surgical methods for men with bothersome urinary symptoms due to an enlarged prostate. It aims to find which approach gives better relief with fewer side effects.
CairoAges 50 years+ - NCT03802851Recruiting
Laser procedure before radiation for prostate cancer symptoms
This trial looks at whether doing a prostate “laser procedure” (called HoLEP) before starting radiation and hormone therapy can improve severe urinary symptoms and reduce urine retention problems. It is for people with prostate cancer who are planning radiation plus hormone treatment and who have significant bladder/urinary trouble.
Kansas City, KansasAges 18 years+ - NCT05678452Recruiting
High-power vs low-power HOLEP for large prostates
This study compares two surgical settings (high power versus low power) during a prostate procedure called HOLEP to see which is safer and works better for people with a large prostate. If you need surgery for an enlarged prostate, this trial may help improve how the procedure is done.
CairoAges 45 years+ - NCT06546865Recruiting
Smaller vs larger scope for prostate surgery: a study
This study compares two sizes of a surgical device (a sheath) used during laser prostate surgery for men with an enlarged prostate. It aims to see if a smaller sheath works as well as the standard larger one, which could make recovery easier.
Thunder Bay, OntarioAges 50 years+ - NCT07020390Recruiting
How anesthesia affects recovery after prostate surgery
This trial compares different anesthesia methods to see which helps patients recover better after HOLEP surgery for an enlarged prostate. Results could help choose the best anesthesia for future patients.
Melikgazi, KayseriAges 18 years+ - NCT07417449Recruiting
Dutasteride before prostate laser surgery and recovery outcomes
This study looks at whether taking dutasteride for at least 6 months before prostate laser surgery affects surgery results and recovery. It includes men having a specific type of prostate surgery called HoLEP.
Ankara, UniversitelerAges 40–80 - NCT07565961Recruiting
Comparing Two Laser Types for Prostate Surgery
This study compares two different laser techniques (HoLEP and ThuLEP) for treating an enlarged prostate that's causing urinary symptoms. Both are minimally invasive surgical options; the trial will help determine which works better for symptom relief.
Munich, BavariaAges 18 years+ - NCT07660068Enrolling by invitation
HoLEP and Sexual Recovery
This study looks at how HoLEP surgery affects sexual function, particularly ejaculation. It's for men who are getting HoLEP to relieve bothersome urinary symptoms.
Chicago, IllinoisAges 18–100 - NCT05719220Recruiting
Group pelvic floor training before HoLEP surgery
This trial tests whether group pelvic floor exercises done before HoLEP surgery can improve recovery and urinary symptoms in men with an enlarged prostate. It may help some people feel better sooner by strengthening the muscles that control urination.
San Francisco, CaliforniaAges 50–90 - NCT04560907Recruiting
Aquablation versus laser procedure for enlarged prostate
This trial compares Aquablation with a laser procedure (HoLEP) to improve urinary symptoms caused by an enlarged, non-cancer prostate. It may help you understand which treatment works better for symptom relief in men with medium-to-large prostates.
Sankt GallenAges 45 years+ - NCT05620784RecruitingPhase 3
Loop water pills during surgery to go home sooner after HoLEP
This trial tests whether giving a “loop diuretic” water pill during surgery can help people after HoLEP go home the same day more often. It’s mainly looking to improve discharge timing while keeping you safe.
Chicago, IllinoisAges 18–89 - NCT05878951RecruitingPhase 2/Phase 3
Botox during HoLEP for men with overactive bladder symptoms
This study tests whether adding a Botox shot into the bladder during HoLEP surgery helps men with overactive bladder symptoms like urgency, frequent urination, and accidents. You’d be compared to the standard approach to see if symptoms improve after surgery.
Chicago, IllinoisAges 18–89 - NCT06668142Recruiting
Beacon platform study for prostate surgery
This trial tests a new surgical platform called Beacon during HoLEP, a common procedure to treat enlarged prostate symptoms. It may help men with difficulty urinating due to an enlarged prostate.
Santiago, Santiago MetropolitanAges 45 years+ - NCT06759194Recruiting
Comparing Two Laser Surgeries for Large Prostate
This trial compares two minimally invasive surgeries to treat a very enlarged prostate (BPH) when medicines are not enough. It aims to see which approach gives better relief for men with large prostates.
AsyutAges 50 years+ - NCT06865430Recruiting
Managing urinary symptoms after HoLEP surgery
This trial tests if alpha-blocker medication can reduce painful or frequent urination after a prostate surgery called HoLEP. It may help you recover more comfortably.
AnkaraAges 40–85 - NCT07603011Recruiting
Catheter timing after prostate laser surgery for urinary problems
This study looks at how long patients should keep a urinary catheter (a tube that drains urine) after having laser surgery to remove prostate tissue. Researchers want to understand what timing works best for patients who couldn't urinate before surgery.
Eskişehir, EskişehirAges 18 years+ - NCT07627178Recruiting
Comparing laser treatments for enlarged prostate
This study compares three different surgical laser techniques to treat benign prostate enlargement (BPH) that causes severe urinary symptoms and hasn't improved with medication. The goal is to find which method is safest and works best for large prostates.
Tanta, Gharbia GovernorateAges Any age - NCT07632742Recruiting
Two laser systems for prostate surgery: which works better?
This study compares two different laser technologies used during a minimally invasive prostate surgery called HoLEP. You'll be randomly assigned to one laser type and asked to complete brief surveys online after your procedure to help doctors understand which works best for reducing urinary symptoms.
Chicago, IllinoisAges 18–100 - NCT07648875Recruiting
Water Vapor vs. Laser Surgery for Enlarged Prostate
This trial compares two minimally invasive surgical procedures for an enlarged prostate that causes urinary problems. Both procedures aim to improve urinary flow while preserving your ability to ejaculate normally.
Banī Suwayf, Beni Suweif GovernorateAges 50 years+
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Common questions
- Are there clinical trials for holep?
- Yes. Clin2 currently lists 22 recruiting holep studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a holep trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a holep trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.