Clinical trials
Humans clinical trials
Below are recruiting humans clinical trials, each written for real people, not researchers. We’re tracking 1,243 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05452564RecruitingPhase 2
Baricitinib to help reduce HIV in the brain
This Phase 2 study tests baricitinib to see if it can lower HIV activity in the brain (CNS) for people already on stable HIV treatment. If you have well-controlled HIV in your blood, this trial looks for additional benefit inside the nervous system.
Atlanta, GeorgiaAges 18–65 - NCT05458440Recruiting
Study using immune cells from recovered COVID-19 donors
This study collects immune cells from people who recovered from COVID-19 and may use them to boost protection against SARS-CoV-2. It’s for hospitalized patients who already show a certain level of COVID-19 fighting immune response.
Vandœuvre-lès-Nancy, LorraineAges 18–70 - NCT05459090Recruiting
Study of how brain “brakes” work in drug-resistant temporal epilepsy
This study looks at how the brain’s natural “braking” system works in people with drug-resistant temporal lobe epilepsy. It may help researchers better understand the condition in order to improve future treatments.
Pozzilli, IserniaAges Any age - NCT05480449RecruitingPhase 1/Phase 2
Personalized CAR-T for children with high-risk B-ALL
This trial studies a personalized type of immune therapy (CAR-T) made from your own cells to treat pediatric B-ALL that has returned or not responded to prior treatment. It aims to see how well this manufactured CAR-T works and how safely it can be given.
Philadelphia, PennsylvaniaAges birth–29 years - NCT05482126Recruiting
Studying brain sensing in advanced Parkinson’s during deep brain stimulation
This study looks at how the brain “filters” sensory information in people with advanced Parkinson’s disease, using brain imaging and deep brain stimulation (DBS) that you may already be getting as routine care. The goal is to better understand what drives Parkinson’s symptoms and how DBS might affect the brain.
Birmingham, AlabamaAges 18–89 - NCT05492344Recruiting
Ultrasound-guided breathing support for severe lung failure
This study tests whether using an ultrasound scan to guide a breathing machine settings can improve care for people with moderate or severe ARDS, a serious lung condition. If you qualify, the team will compare the ultrasound-guided approach to standard ventilator care in the ICU.
BrusselsAges 18–100 - NCT05491512RecruitingPhase 2
Reduced radiation with chemo for HPV throat cancer
This trial tests whether giving less radiation (while using standard chemotherapy) can treat HPV-related throat cancer effectively. It may help reduce radiation exposure while still controlling the cancer.
Basking Ridge, New JerseyAges 18 years+ - NCT05495295RecruitingPhase 1
First test of PhOx430 for advanced solid tumors
This Phase 1 trial tests a new cancer drug, PhOx430, for people with advanced (metastatic) solid tumors that have not responded to standard treatments. It aims to find a safe dose and to see whether the drug can shrink or control cancer.
MontpellierAges 18–80 - NCT05505513Recruiting
Test micro-electrode nerve implants for hand signal feedback
This study looks at whether tiny implanted sensors in a nerve can record brain/nerve signals and use them to provide feedback for people with a transradial arm amputation. If it works, it could help improve control or awareness with a prosthetic hand or related devices.
Salt Lake City, UtahAges 18–65 - NCT05514223Recruiting
Testing sperm samples to understand lifestyle, gut, and sperm quality
This study measures “free radicals” in sperm to see how lifestyle and the microbiota (gut/community of microbes) may relate to sperm health. You may be asked to provide a semen sample as part of standard fertility testing, unless certain health factors apply.
Groningen, Provincie GroningenAges 18–55 - NCT05529264Recruiting
EEG study in adults with epilepsy and brain recordings
This study uses brain recordings to better understand epilepsy signals. It may help people who need EEG monitoring for clinical care, and it may also use healthy adults as comparison participants.
Lebanon, New HampshireAges 18 years+ - NCT05537935RecruitingPhase 4
Low-dose naltrexone for nerve pain in people with HIV
This trial studies whether a low dose of naltrexone can reduce long-lasting nerve-related pain in adults living with HIV. It may help if your pain has been ongoing and you have stable HIV control.
Atlanta, GeorgiaAges 18–75 - NCT05539638Recruiting
Testing blood DNA for head and neck squamous cancer
This study looks at how tumor DNA found in a blood sample (a “DNA signal”) relates to head and neck cancer in the oropharynx. It may help doctors understand disease status and improve how they monitor treatment, for both HPV-positive and HPV-negative cancers.
Dundee, DD2 1SGAges 18 years+ - NCT05541016RecruitingPhase 2
Personalized lower-dose radiation for HPV-related throat cancer
This Phase 2 study tests whether giving a less intense (de-escalated) radiation plan can work for certain people with HPV-related oropharyngeal throat cancer. It uses HPV blood testing and scans to help guide treatment, aiming to keep cancer control while reducing treatment side effects.
Scottsdale, ArizonaAges 18 years+ - NCT05548322Recruiting
Testing touch feedback for prosthetic limbs in healthy people
This study tests how well a prosthetic touch system can give realistic sensory feedback. It aims to improve how prosthetic users feel touch and movement, based on controlled testing in volunteers.
MarseilleAges 20–70 - NCT05553743Recruiting
Study of donated breast milk and how it affects child health
This study looks at breast milk donated for research and how it may relate to infant and child health. If you’re an adult who is breastfeeding and can donate extra milk, you may be able to participate.
San Diego, CaliforniaAges 18 years+ - NCT05556473RecruitingPhase 1
Tryptophan PET/CT scan study for different tumors
This early-phase study tests a special PET/CT scan using labeled tryptophan to help doctors see how different tumors behave. The goal is to learn whether this scan can better identify and measure cancers in the brain or elsewhere.
Detroit, MichiganAges 18 years+ - NCT05558501RecruitingPhase 1/Phase 2
Intermittent low-oxygen therapy for sleep apnea and health risks
This early-stage study tests a treatment that briefly reduces oxygen during sleep to improve “plasticity,” with the goal of helping people with obstructive or mixed sleep apnea. It also looks at related conditions like high blood pressure and pre-diabetes or cholesterol problems, especially in people who haven’t tried CPAP yet.
Detroit, MichiganAges 30–60 - NCT05586802RecruitingPhase 3
Balancing sex hormones to improve metabolism and fertility in Klinefelter
This study tests whether adjusting sex-hormone levels can improve body metabolism and reproductive hormone balance in people with Klinefelter syndrome. Depending on the design, you may be looking at fertility preservation and/or metabolic health.
LausanneAges 16–65 - NCT05588167Recruiting
Niemann-Pick type C patient database and genetic data study
This study collects health information and genetic samples from people diagnosed with Niemann-Pick disease type C. The goal is to build a large database that can help researchers better understand the condition and improve future care.
Bethesda, MarylandAges 3 months+ - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT05600946Recruiting
Study of body differences in creatine transporter deficiency
This study looks at physical and body features in people with creatine transporter deficiency caused by a specific gene change (SLC6A8). It may help doctors better understand the condition and how it shows up, which can improve future care.
Bethesda, MarylandAges 2–40 - NCT05601726RecruitingPhase 1/Phase 2
Study of a new drug for hard-to-treat AML or high-risk MDS
This early study tests a new medicine (ABD-3001) to see if it’s safe and tolerable, how the body handles it, and whether it shows early signs of helping people with relapsed or hard-to-treat AML or high-risk MDS. It may be an option if standard treatments have already failed and you can’t receive a stem cell transplant.
Marseille, FranceAges 18 years+ - NCT05604534Recruiting
MRI tests to improve brain scan measurements
This study uses MRI scans to check and improve how medical teams measure brain changes. If you’re eligible, you’ll complete MRI safety screening and imaging while the team studies which scan measurements work best.
Bethesda, MarylandAges 18–100
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Common questions
- Are there clinical trials for humans?
- Yes. Clin2 currently lists 1,243 recruiting humans studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a humans trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a humans trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.