Clinical trials
Humans clinical trials
Below are recruiting humans clinical trials, each written for real people, not researchers. We’re tracking 1,243 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05606133Recruiting
Test HPV DNA from blood to track cervical cancer risk
This study looks at a blood test that measures HPV DNA to help screen and monitor people with HPV-related cervical problems. If you have confirmed high-grade cervical changes or cervical cancer, the test may help doctors follow how your condition changes over time.
New York, New YorkAges 18 years+ - NCT05607498RecruitingPhase 1
First study of EMB-07 for advanced cancers or lymphoma
This Phase 1 trial tests EMB-07, a new treatment, in people with advanced or hard-to-treat solid tumors or certain relapsed/refractory lymphomas. The goal is to find a safe dose and learn whether it can shrink tumors.
Frankston, VictoriaAges 18 years+ - NCT05621668RecruitingPhase 1
First drug trial using engineered T-cells for sarcoma
This Phase 1 trial tests a new immune therapy made from your T-cells and engineered to target sarcoma tumors. It is designed to see if the treatment is safe and whether it can shrink advanced or metastatic soft tissue or bone sarcoma.
Houston, TexasAges 12 years+ - NCT05627960RecruitingPhase 1
Testing an antibody drug for advanced solid cancers
This Phase 1 study tests AG01, an antibody that targets a cancer protein called GP88, in people with advanced solid tumors. The goal is to find safe doses and learn whether it can help certain cancers.
Baltimore, MarylandAges 18 years+ - NCT05640700Recruiting
Study of vaginal microbiome in HPV-related early cell changes
This study looks at the vaginal “microbiome” (the normal germs and bacteria in the vagina) in people who have had abnormal Pap smear or colposcopy results related to HPV. It may help doctors understand what to monitor and how to better identify early, pre-cancer changes in the cervix.
JerusalemAges 25–70 - NCT05643079Recruiting
Bone screw and tendon transfer for heel bone realignment
This trial studies a specific surgical technique for people who need heel bone realignment along with a tendon transfer. It tests whether using a human donor bone screw helps the bone heal and the tendon work after surgery.
ViennaAges 18 years+ - NCT05642858Recruiting
Learn heart health tips for people living with HIV
This study tests a text-message education program to help people living with HIV manage cardiovascular (heart and blood vessel) health. It may be helpful if you are 40 or older and can use a smartphone to receive messages.
San Francisco, CaliforniaAges 40 years+ - NCT05648448RecruitingPhase 2
Early flu antiviral trial for adults with confirmed influenza
This Phase 2 study compares antiviral medicines in adults who have early, flu-like symptoms and test positive for influenza. It aims to see which antiviral treatment works best and is safe for people treated soon after symptoms start.
Minas GeraisAges 18–60 - NCT05650255Recruiting
Testing a digital twin to guide an exoskeleton training pilot
This study tests a “digital twin” computer model to help guide an exoskeleton (an assisted device for walking) during a small pilot program. You may be invited if you can stand and walk independently for over 5 minutes and don’t have certain nerve or leg joint problems.
Taipei,TaiwanAges 18–80 - NCT05661903RecruitingPhase 2
Spinal cord stimulator study for nerve pain and brain effects
This Phase 2 study looks at how spinal cord (or nerve-root) stimulation affects pain signals in the brain and body. You may qualify if you already have a stimulator set to a comfort mode that avoids “tingling” sensations.
Boston, MassachusettsAges 18–80 - NCT05662189Recruiting
PET scan study of beta cell function in diabetes
This study uses a special PET scan to measure how well insulin-producing cells (“beta cells”) in the pancreas are working in people with diabetes. It’s meant to help researchers understand diabetes biology and test whether the scan can reflect beta cell function.
Parma, PrAges 18–75 - NCT05672927RecruitingPhase 4
Comparing HPV vaccine schedules: 2 doses vs 3 doses
This study compares how well your immune system responds to an HPV vaccine given as either 2 doses or 3 doses in people ages 27–45 who have never had the HPV vaccine. It may help improve HPV prevention strategies and guide the best dose schedule for adults.
Galveston, TexasAges 27–45 - NCT05686226RecruitingPhase 2
Trial tests immune cells targeting HPV-16 cancers
This Phase 2 trial tests an immune-cell treatment (E7 TCR T cells) designed to attack cancers caused by HPV type 16. It may help people whose HPV-16+ cancer has come back or not responded to standard treatment.
Bethesda, MarylandAges 18 years+ - NCT05688683Recruiting
Brain recording during awake surgery to study motor learning
This study uses special brain recordings during an awake surgical procedure to understand how the brain learns new movement and sensation skills. If you can comfortably take part in a simple task during surgery, you may help researchers learn how learning works in humans.
ParisAges 18 years+ - NCT05692830Recruiting
Test a wearable patch to estimate blood alcohol level
This study checks how accurately a new wearable skin patch estimates your blood alcohol level. It uses larger human testing and computer methods to improve the patch’s accuracy.
Champaign, IllinoisAges 21 years+ - NCT05724641Recruiting
MRI test of eye blood flow in specific optic nerve conditions
This study uses a special MRI scan to measure blood flow to the eye and check how consistently the results match over time. It may help doctors better assess certain optic nerve problems, especially in people without major cardiovascular risk factors.
Brussels, Brussels CapitalAges 18 years+ - NCT05729061Recruiting
Testing movement with mobility assistive devices
This study measures how people move while using assistive devices during guided movement tasks, sometimes on a treadmill. It may help improve these tools and how safely they support different types of movement needs.
Edmonds, WashingtonAges 18–90 - NCT05735080RecruitingPhase 1/Phase 2
INX-315 for advanced cancers with a specific gene change
This trial studies an experimental medicine (INX-315) given in an “open-label” way to people with advanced cancer that has not responded to prior treatment. It mainly looks at safety and side effects first, and also checks how well it works in cancers with a specific gene amplification.
Orlando, FloridaAges 18 years+ - NCT05743868Recruiting
Study of how insulin resistance affects blood fats
This study looks at how differences in insulin resistance may change how the liver makes triglycerides (a type of blood fat). It may help researchers understand why some people have higher triglycerides and how to target them better.
AmsterdamAges 18–65 - NCT05746897RecruitingPhase 1
First-in-human test of an anti-PVRIG drug for advanced cancers
This early-phase study tests NM1F (an anti-PVRIG antibody) in people with advanced solid tumors to see if it’s safe and whether it may work. It also includes pembrolizumab (a PD-1 “checkpoint” medicine), aiming to boost the immune system against the cancer.
Dallas, TexasAges 18 years+ - NCT05748834RecruitingPhase 2
Tucatinib plus Doxil for HER2-positive metastatic breast cancer
This Phase 2 study tests tucatinib (a HER2-targeted pill) plus Doxil (a chemotherapy medicine) to slow or shrink HER2-positive metastatic breast cancer that has been treated before. It may help by targeting HER2 cancer cells more effectively than past treatments alone.
Columbia, MarylandAges 18 years+ - NCT05753722RecruitingPhase 1
First trial for PRTH-101 alone or with pembrolizumab
This early study tests PRTH-101, given by itself or with pembrolizumab, in people with advanced cancers that have spread or cannot be removed by surgery. The goal is to see if it is safe and how it affects the cancer.
Scottsdale, ArizonaAges 18 years+ - NCT05753839Recruiting
Testing surgery plus immunotherapy for metastatic kidney cancer
This trial studies whether removing the kidney tumor (cytoreductive nephrectomy) before treatment can improve outcomes for people with metastatic clear-cell kidney cancer. All participants are expected to receive standard immunotherapy (nivolumab plus ipilimumab), and the study focuses on the role of surgery in the “immuno-oncology era.”
SeoulAges 18 years+ - NCT05761756Recruiting
Study of oxygen side effects in otherwise healthy adults
This study looks at what happens in the body when oxygen levels are too high, to better understand the mechanism of oxygen toxicity. You may be eligible if you are a healthy, non-smoking adult without certain medical conditions.
Durham, North CarolinaAges 18–45
Hear when a new Humans trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for humans?
- Yes. Clin2 currently lists 1,243 recruiting humans studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a humans trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a humans trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.