Clinical trials
Hyperbaric Oxygenation clinical trials
Below are recruiting hyperbaric oxygenation clinical trials, each written for real people, not researchers. We’re tracking 48 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07368647Recruiting
Hyperbaric oxygen for radiation cystitis symptoms
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve symptoms and reduce inflammation in people with bladder damage from past pelvic radiation. It compares patients with radiation cystitis to those without it.
Lebanon, New HampshireAges 18 years+ - NCT07489274RecruitingPhase 4
Hyperbaric oxygen for severe skin infections
This trial tests whether adding hyperbaric oxygen therapy to standard care helps adults with a serious soft-tissue infection. It could improve healing and reduce complications.
Antwerp, EdegemAges 18 years+ - NCT07473362Recruiting
Oxygen therapy in a high pressure chamber for PTSD
This trial tests whether breathing pure oxygen in a high-pressure chamber can help reduce symptoms of post-traumatic stress disorder (PTSD) in military veterans. It involves 60 daily sessions over 12 weeks, and aims to include both men and women.
Ramat Gan, Tel AvivAges 18–80 - NCT07361861Recruiting
Hyperbaric oxygen for fitness and inflammation in healthy adults
This trial is testing whether breathing pure oxygen in a pressurized chamber (called hyperbaric oxygen therapy) can improve your fitness and lower inflammation. You may qualify if you’re a healthy, active adult aged 30–60.
Austin, TexasAges 30–60 - NCT06452095Recruiting
Hyperbaric oxygen therapy for long COVID brain fog
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) helps with long COVID symptoms, especially brain fog and thinking problems. It may be an option if you have had lingering symptoms for at least 2 months and can travel to one of the study sites.
Toronto, OntarioAges 18 years+ - NCT07410169RecruitingPhase 2/Phase 3
Oxygen therapy for chemo-related nerve pain in breast cancer
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can reduce nerve pain caused by the chemotherapy drug nab-paclitaxel in breast cancer patients. It may help women who have finished chemo and are still dealing with numbness, tingling, or pain in their hands or feet.
Guangzhou, GuangdongAges 18–75 - NCT03594344Recruiting
Extra hyperbaric oxygen after leg amputation wounds heal
This study tests whether giving extra treatments with hyperbaric (pressure) oxygen after a leg amputation can improve healing or recovery. It’s meant for people whose amputation happened due to long-lasting infection or poor blood flow and who can attend follow-up visits.
OsloAges 18–90 - NCT03964506RecruitingEarly Phase 1
Hyperbaric oxygen plus donor stem cell transplant for blood cancers
This early-phase trial studies whether breathing pure oxygen in a pressurized chamber, along with a donor stem cell transplant, can improve outcomes for certain blood cancers. It may help by supporting the body during transplant and recovery, but it is still being tested for safety and effectiveness.
Rochester, New YorkAges 18–75 - NCT07257588Enrolling by invitation
Hyperbaric oxygen for severe ulcerative colitis
This study tests whether adding hyperbaric oxygen therapy—breathing pure oxygen in a pressurized chamber—to standard care can help people with a severe flare of ulcerative colitis (a type of inflammatory bowel disease). It may reduce inflammation and speed up recovery.
Xi'an, ShaanxiAges 18 years+ - NCT07852728RecruitingPhase 2
Oxygen therapy for first responders after head injuries
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and overall well-being in first responders who have had a traumatic brain injury and still have symptoms. If you are a first responder dealing with ongoing brain injury symptoms, this study could help you find new ways to feel better.
Boise, IdahoAges 18–75 - NCT07732374RecruitingPhase 2
Long-term results after hyperbaric oxygen therapy in veterans
This study follows veterans who previously finished a 40-session hyperbaric oxygen therapy (HBOT) program. It tracks how their memory, mood, and daily function are doing 12 weeks later, to understand long-term benefits.
Boise, IdahoAges 18 years+ - NCT06579040Recruiting
Hyperbaric oxygen for endometriosis pain
This trial tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help reduce endometriosis-related pelvic pain. It is for people with ongoing moderate to severe pain who are waiting for surgery.
Toronto, OntarioAges 18 years+ - NCT06581003RecruitingPhase 3
Hyperbaric oxygen for veterans with lasting brain injury symptoms
This trial tests whether breathing pure oxygen inside a pressurized chamber (hyperbaric oxygen therapy) can help reduce long-term symptoms after a mild or moderate traumatic brain injury. It is for veterans and service members who have had a TBI at least one year ago and are still struggling with symptoms.
Tampa, FloridaAges 18–75 - NCT07662629Recruiting
Hyperbaric oxygen and exercise for breast cancer pain
This study tests if adding hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) to a gentle exercise program can help reduce bone, joint, or muscle pain caused by hormone therapy in older women who had breast cancer.
Dokki, Giza GovernorateAges 65–75 - NCT04791488Recruiting
Testing oxygen level effects after diving or oxygen therapy
This study looks at how breathing extra oxygen (hyperoxia) and the body’s immune response change after diving or when people need hyperbaric oxygen therapy. It may help doctors understand what to expect and how to manage recovery after a diving accident.
ToulonAges 18 years+ - NCT04490317Recruiting
Study follows people with carbon monoxide poisoning in Korea
This study looks at people who have been sickened by carbon monoxide (CO) from an accident or exposure. It aims to better understand what happens over time, which could help improve care and outcomes in the future.
Wŏnju, Gangwon-doAges Any age - NCT07659301Recruiting
Breathing extra oxygen after cycling to speed recovery
This study tests how breathing higher-than-normal levels of oxygen for a short time after a hard bike ride affects your recovery. It is designed for competitive road cyclists who want to recover faster and perform better in their next training or race.
Louvain-la-Neuve, Brabant-WallonAges 18–40 - NCT07626450Recruiting
Hyperbaric oxygen after stroke clot removal treatment
This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help recovery after emergency clot-removal surgery for large blood vessel strokes. The goal is to see if extra oxygen can reduce brain damage and improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT07558928Recruiting
High-oxygen environment and muscle strength in active adults
This study tests whether exercising in a high-oxygen environment can help build stronger muscles faster. Researchers will have you do resistance training (like weightlifting) in a special chamber with extra oxygen to see if it boosts your muscle gains.
ZrifinAges 18–45 - NCT07430150Recruiting
Long-term effects of oxygen therapy on thinking after brain injury
This study checks if hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) has lasting benefits for thinking skills in people who have had a traumatic brain injury.
ZrifinAges 18 years+ - NCT05697328Recruiting
Testing barotrauma effects of hyperbaric oxygen
This study looks at problems caused by pressure changes during hyperbaric oxygen therapy (HBOT). It may help the team understand risks and how to keep treatment safer while you get HBOT.
Walnut Creek, CaliforniaAges 18 years+ - NCT06055257RecruitingPhase 3
Combination therapy for jaw bone damage after radiation
This trial tests a combination of hyperbaric oxygen therapy and a medication called PENTOCLO to treat osteoradionecrosis (bone damage) in the jaw after radiation treatment for cancer. It may help heal the exposed bone.
Toronto, OntarioAges Any age - NCT06408363Recruiting
Ear pressure maneuvers for first hyperbaric session
This trial looks at whether doing a specific sequence of ear pressure-equalization moves helps people during their first hyperbaric oxygen therapy session. It might help you if you're about to start this treatment.
Belo Horizonte, Minas GeraisAges Any age - NCT04855396Recruiting
Study of blood markers during hyperbaric oxygen brain injury care
This trial looks at blood “biomarkers,” or lab measurements, while people receive hyperbaric oxygen treatment for brain injury as part of the main HOBIT study. It may help researchers understand who benefits and why by improving how treatment responses are tracked.
San Diego, CaliforniaAges 16–65
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Common questions
- Are there clinical trials for hyperbaric oxygenation?
- Yes. Clin2 currently lists 48 recruiting hyperbaric oxygenation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hyperbaric oxygenation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hyperbaric oxygenation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.