Clinical trials
Extracorporeal Membrane Oxygenation clinical trials
Below are recruiting extracorporeal membrane oxygenation clinical trials, each written for real people, not researchers. We’re tracking 52 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06602557RecruitingPhase 2
Inhaled antibiotic for lung infection during ECMO support
This trial tests whether adding an inhaled antibiotic (amikacin) to standard IV antibiotics can better treat a serious lung infection (pneumonia caused by Gram-negative bacteria) in patients on a heart-lung machine (ECMO) and a breathing tube. If you or your loved one is on ECMO and has this type of pneumonia, this study may offer a new treatment approach.
ParisAges 18 years+ - NCT05237232Recruiting
MRI study of blood vessel changes after ECMO in infants
This study uses a brain MRI with a special blood-vessel scan to see how circulation changes after a life-support machine called ECMO in young children. It may help doctors better understand what happens in the brain after ECMO and improve care.
ParisAges Up to 17 years - NCT05959252RecruitingPhase 2
Bivalirudin vs heparin for blood thinning during ECMO
This Phase 2 trial compares two blood-thinning medicines—bivalirudin and heparin—in people on ECMO (a machine that supports breathing and/or circulation). It aims to see which medicine works better and is safer while you are connected to the ECMO circuit.
Sydney, New South WalesAges 18 years+ - NCT05664204Recruiting
ECMO before or after lung transplant to improve outcomes
This study looks at using a heart–lung machine (ECMO) to reduce complications and deaths after a lung transplant. It focuses on people getting a lung transplant who have certain types of lung-vessel (pulmonary) pressure problems.
ParisAges 18 years+ - NCT05303363Recruiting
Checking brain blood flow during a breathing heart-lung machine
This study monitors how much blood is reaching the brain in adults who need a specific type of life-support called VV-ECMO. The goal is to better understand brain blood flow and how monitoring may help manage care during ECMO.
Amsterdam-ZuidoostAges 18–100 - NCT06275555Recruiting
Bivalirudin for blood thinning in ECMO patients
This trial tests if bivalirudin is a safe and effective blood thinner for people on ECMO, a machine that helps your heart and lungs. You may be eligible if you need this therapy and have no past reactions to similar medicines.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06792617Enrolling by invitationEarly Phase 1
Exercise for people on ECMO life support
This study tests if gentle exercise in bed can help people on ECMO (a life-support machine for heart and lungs) get stronger and recover faster. It is for adults in the ICU who are stable enough to move safely.
San Antonio, TexasAges 18 years+ - NCT04330651Recruiting
Extra-support machine for heart patients after surgery
This study looks at using an external life-support machine after heart surgery. It may help patients who need temporary extra support while the heart and body recover.
FlorenceAges 18–80 - NCT05163925Recruiting
Study of a heart-lung device for emergency life support
This trial looks at using a specific heart-lung support machine (the EUROSETS ECMOLIFE system) for adults who need urgent “extra” circulation support. It may help clinicians understand how well the device works in serious situations like shock, cardiac arrest, or after heart surgery.
ViennaAges 18 years+ - NCT05527717RecruitingPhase 4
PCI vs strategy for heart attack shock needing ECMO
This study looks at the best way to reopen blocked heart arteries (using a stent procedure) in people who had a heart attack complicated by severe shock and need a life-support machine called VA-ECMO. It may help improve outcomes by testing which revascularization approach works best for multi-vessel blockages.
SeoulAges 19 years+ - NCT06152744Recruiting
Testing ECMO lung function at high altitude
This study looks at how well the ECMO machine works in high-altitude areas. It tests the oxygen exchange in the machine to help improve care for patients at high elevations.
Beijing, Beijing MunicipalityAges 18–70 - NCT06766006Recruiting
Heart-lung machine left ventricle unloading study
This study looks at how to best relieve pressure on the heart while a heart-lung machine is helping to pump blood. It includes anyone who needs this support.
MaastrichtAges 1 day–80 years - NCT06814340RecruitingPhase 3
CPAP on ECMO for severe lung failure
This trial is for people with severe lung failure (ARDS) who are already on a life-support machine called VV-ECMO. It tests whether adding a special breathing tube (CPAP) can help their lungs heal better.
BobignyAges 18 years+ - NCT07113769Recruiting
Biomarkers and platelets in CPR patients
This trial is studying the blood biomarkers and platelet characteristics in patients who receive CPR and are then placed on a heart-lung bypass machine (ECPR). It aims to understand how these biological markers relate to patient outcomes.
Zhengzhou, HenanAges 18 years+ - NCT05699005RecruitingPhase 1
Personalized or standard blood transfusion during heart-lung machine
This trial tests whether giving blood in a personalized way, instead of a standard approach, is better for people on a heart-lung bypass machine (VA-ECMO) for heart-related shock. It may help find a safer blood transfusion strategy while you are critically ill.
Lille, NORDAges 18 years+ - NCT05440851Recruiting
Testing different treatments for severe breathing failure in ICU
This platform trial studies which treatment works best for adults with sudden, severe breathing failure needing oxygen or a breathing machine in the ICU. It may help patients by matching them to the most appropriate treatment strategy and tracking outcomes to improve care.
Tucson, ArizonaAges 18 years+ - NCT03593408Recruiting
Study drug levels in children on ECMO
This study measures how sedating and pain medicines move through the body in children who are supported by ECMO (a heart-lung machine). It may help doctors choose safer and more effective dosing for sedation and pain control during ECMO.
Boston, MassachusettsAges birth–17 years - NCT06560164Recruiting
Comparing blood transfusion levels in ECMO patients
This trial tests whether giving more or fewer red blood cell transfusions is better for adult patients on ECMO (a machine that helps your heart and lungs work). The goal is to find the best transfusion approach to improve outcomes.
Vienna, State of ViennaAges 18 years+ - NCT06469801Recruiting
Portable MRI for brain injury in children on ECMO
This study uses a portable MRI to look for brain injuries in children on ECMO (a heart-lung support machine). It may help doctors detect problems early and improve care.
Kansas City, MissouriAges birth–17 years - NCT05565495RecruitingPhase 2
Hydromorphone dosing changes during ECMO
This Phase 2 study looks at how hydromorphone (a strong pain medicine) behaves in the body for people on ECMO, and how that may affect dosing. It may help doctors better choose the right pain-med dose while someone is receiving ECMO.
Wuhan, HubeiAges 18–80 - NCT06426836Recruiting
Better antibiotic dosing for children on ECMO
This trial studies how to give the right dose of common antibiotics to children on ECMO (a heart-lung bypass machine). The goal is to help doctors choose the best dose to fight infections while keeping the child safe.
Brussels, Brussels CapitalAges Up to 15 years - NCT06276010Recruiting
Nafamostat mesilate for blood thinning in ECMO patients
This trial tests a medicine called nafamostat mesilate to prevent blood clots in patients who need ECMO (a machine that helps your heart and lungs) after heart surgery. It may offer a safer way to thin the blood compared to standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05814094Recruiting
Testing a red blood transfusion approach during ECMO
This study looks at whether giving red blood cell transfusions in a specific way is practical and safe for people receiving ECMO (a heart-lung support machine). It’s mainly a feasibility study, meaning the goal is to see if the plan can be carried out smoothly and safely.
Camperdown, New South WalesAges 18 years+ - NCT02851758Recruiting
Autologous mitochondria treatment for critically ill heart children on ECMO
This trial looks at giving a child their own mitochondria to help protect the heart from injury caused by reduced blood flow. It is for children with serious heart problems who are on a heart-lung machine and may have signs of ischemia (reduced blood flow damage).
Boston, MassachusettsAges Up to 17 years
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Common questions
- Are there clinical trials for extracorporeal membrane oxygenation?
- Yes. Clin2 currently lists 52 recruiting extracorporeal membrane oxygenation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a extracorporeal membrane oxygenation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a extracorporeal membrane oxygenation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.