Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 982 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06646198RecruitingPhase 2
TIPS with half-dose Donafenib for liver cancer with portal hypertension
This trial tests a treatment that combines a procedure called TIPS with a targeted therapy drug (Donafenib) at half strength. It is for people with advanced liver cancer that has spread into the portal vein and caused high blood pressure in the liver (portal hypertension). The goal is to see if this combination can help control the cancer and reduce complications.
Guangzhou, GuangdongAges 18–75 - NCT05843500Recruiting
CTEPD and CTEPH registry for long-term blood-clot lung disease
This study builds a registry to learn about people with chronic blood-clot lung disease (CTEPD/CTEPH) and what symptoms and test results look like over time. It may help clinicians better understand the condition and improve future care, since your participation supports data collection rather than a new drug.
San Francisco, CaliforniaAges 18 years+ - NCT05110066Recruiting
Compare two procedures for chronic lung blood-clot pressure
This study compares balloon pulmonary angioplasty versus pulmonary endarterectomy for people with chronic thromboembolic pulmonary hypertension (high blood pressure in the lungs due to long-lasting blood clots). It may help find which procedure works better for improving symptoms and lung circulation after treatment.
AarhusAges 18–79 - NCT02282748Recruiting
Swiss long-term health study for local residents
This trial is a long-term study that follows people over time to learn about health patterns in specific Swiss areas. Your participation may help researchers better understand long-term health changes and how to improve care.
Uznach, Canton of St. GallenAges 6 years+ - NCT04031508Enrolling by invitationPhase 2
Omega-3 in an IV for newborns with breathing circulation problems
This trial tests whether giving an omega-3 fat medicine through an IV (along with standard care) improves breathing and blood-flow problems in newborns with congenital diaphragmatic hernia and persistent pulmonary hypertension. It may help reduce strain on the lungs and heart by targeting inflammation and blood-vessel changes.
Mexico City, Mexico CityAges 1 hour–2 weeks - NCT04206852Recruiting
Balloon treatment for chronic blood-clot lung vessel disease
This trial tests whether a procedure called balloon pulmonary angioplasty is safe and effective for people with chronic thromboembolic disease in the lungs, especially when surgery isn’t an option. If you have CTEPH, it may help improve lung blood flow and symptoms.
BeijingAges 18 years+ - NCT03496792Recruiting
Study of blood pressure changes when standing up
This study checks how your blood pressure changes when you go from lying down to standing. It may help researchers understand why some people get “orthostatic hypertension” (higher blood pressure when standing) and how that reflex works.
Hershey, PennsylvaniaAges 18 years+ - NCT06447740Recruiting
Stent vs. medication for narrowed kidney artery
This trial compares placing a tiny mesh tube (stent) to open the narrowed kidney artery versus continuing blood pressure medicines alone. It is for people whose high blood pressure is hard to control even with multiple medications and who have a blockage in the kidney artery that can be treated.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06861075Recruiting
Carvedilol for high blood pressure in liver veins
This trial tests whether a medicine called carvedilol can lower high blood pressure in the liver veins of people with cirrhosis. It uses a special ultrasound probe to measure the pressure before and after taking the medicine.
Clermont-FerrandAges 18 years+ - NCT07051603RecruitingPhase 1
Safety study of SAL0140 in healthy Chinese adults
This study tests the safety and how the body handles a new medicine (SAL0140) in healthy people. It helps doctors find the right dose and check for side effects.
Guangzhou, GuangdongAges 18–65 - NCT06556407Recruiting
Kidney nerve treatment for high blood pressure in dialysis patients
This trial tests a procedure called renal denervation (using radio waves to calm overactive nerves in the kidney) to see if it helps lower blood pressure in people on dialysis who have resistant high blood pressure.
Erlangen, BavariaAges 18–99 - NCT05967299RecruitingPhase 1
IV ZMA001 study in healthy adults
This Phase 1 trial tests how an IV medicine called ZMA001 behaves in healthy people and checks for early safety. It may help future studies of the drug by confirming dosing and effects in people before testing in patients.
Bethesda, MarylandAges 18–60 - NCT06543394Enrolling by invitation
Helping patients take blood pressure medication regularly
This trial tests whether a behavioral science approach can help people with high blood pressure take their medication as prescribed. If you have trouble remembering or sticking with your blood pressure pills, this study may help you find better ways to stay on track.
New York, New YorkAges 18 years+ - NCT05703191Recruiting
Tests an inhaled nitric oxide system for newborn lung pressure
This study looks at whether an inhaled nitric oxide generator and delivery system can help newborns with high lung blood pressure (pulmonary hypertension). It may help improve oxygen levels during breathing support, but it requires specific medical eligibility and informed consent.
Guangzhou, GuangzhouAges Any age - NCT06852924Recruiting
Inhaled nitric oxide for HAPE treatment trial
This trial tests if inhaled nitric oxide helps people with high-altitude pulmonary edema (fluid in the lungs from high altitude). It may offer a new treatment option for those with mild to moderate symptoms.
Lhasa, TibetAges 18–65 - NCT06518915Recruiting
Baroloop trial for stubborn high blood pressure
This trial tests a device that helps control blood pressure by gently stimulating a nerve in your neck. It may help if your blood pressure stays high even while taking three different medications.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT06922240RecruitingPhase 3
Stopping riociguat to see how the heart responds in CTEPH
This trial is for people with a type of long-term blood clot in the lungs (CTEPH) who have been taking riociguat for at least 12 weeks. It will see what happens when the medication is stopped, focusing on how the right side of the heart is doing.
Beijing, ChinaAges 18 years+ - NCT06845579Recruiting
Predicting blood pressure results after kidney nerve treatment
This study tests a treatment called renal denervation, which uses a special procedure to calm nerves near the kidneys that can raise blood pressure. It may help people whose high blood pressure is not well controlled despite taking several medications.
Mainz, Rheinland PflanzAges 18 years+ - NCT07184814Recruiting
Takayasu's arteritis with lung artery involvement study
This study looks at people with Takayasu's arteritis that also affects the lungs' blood vessels. Researchers want to understand the disease's behavior and outcomes over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06555900Recruiting
Predicting brain pressure spikes in injured patients using AI
This study is testing if an artificial intelligence program can predict dangerous increases in pressure inside the skull of people with brain injuries. If successful, it could help doctors treat these episodes sooner.
BrestAges 18–99 - NCT07247877Enrolling by invitation
Study of small liver grafts for portal hypertension treatment
This trial explores using smaller liver grafts in a partial transplant to treat portal hypertension, which may help patients avoid full transplant risks. It compares this approach to standard liver transplant.
Ages 14 years+ - NCT06855407Recruiting
Blood pressure and brain blood flow during anesthesia study
This study looks at how blood pressure medicines affect blood flow to the brain during general anesthesia for planned surgery. It may help doctors understand how to better manage care during operations.
UmeåAges 50–80 - NCT07081243Recruiting
A study on a procedure for hard-to-treat high blood pressure
This study looks at a procedure called renal denervation, which uses a device to calm overactive nerves in the kidneys that can drive high blood pressure. It is for people whose blood pressure stays high even with several medications, or who cannot tolerate blood pressure pills.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07352228Enrolling by invitationPhase 4
Comparing carvedilol and propranolol to prevent variceal rebleeding
This trial tests whether carvedilol or propranolol works better to prevent another bleeding episode from enlarged veins in the stomach or esophagus (varices) after they have been treated with endoscopy. If you have cirrhosis and had a variceal bleed 6 to 30 days ago, this study may help find the most effective medicine for you.
Xi'anAges 18–75
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 982 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.