Clinical trials
Immunity clinical trials
Below are recruiting immunity clinical trials, each written for real people, not researchers. We’re tracking 1,069 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07605845RecruitingPhase 1
Testing GL-2045 Safety in Immune Thrombocytopenia Patients
This trial tests a new drug called GL-2045 for immune thrombocytopenia (ITP)—a condition where your body destroys its own platelets, causing low platelet counts and bleeding risks. The study checks if GL-2045 is safe and effective for people whose platelet counts haven't been controlled well enough with other treatments.
LeedsAges 18–80 - NCT07644897RecruitingPhase 2
Thymosin Alpha 1 Plus Anti-PD-1 for Advanced Melanoma in Older Adults
This trial tests a combination of two drugs—thymosin alpha 1 (an immune-boosting protein) and an anti-PD-1 antibody (a cancer immunotherapy)—in patients 60 and older with advanced melanoma that cannot be surgically removed. The goal is to help the immune system fight the cancer more effectively.
Guangzhou, GuangdongAges 60 years+ - NCT07652580Recruiting
Toxins, immunity, and B-cell lymphoma
This study looks at how exposure to toxins might affect your immune system if you have B-cell non-Hodgkin lymphoma. You'll provide blood and skin samples, plus have your genes sequenced, to help researchers find links between environmental exposures and lymphoma.
Bethesda, MarylandAges 4 years+ - NCT07657793RecruitingPhase 2/Phase 3
Sirolimus for Lupus-Related Low Platelets
This trial tests sirolimus, an immune-system-calming medicine, for people with lupus who also have very low platelet counts (ITP). It may help reduce bleeding risk and improve platelet numbers.
Beijing, Beijing MunicipalityAges 18–65 - NCT07656090Enrolling by invitationEarly Phase 1
Testing IDOV-Immune for advanced solid tumors
This trial tests an investigational drug called IDOV-Immune for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if it is safe and effective.
Beijing, Beijing MunicipalityAges 18–75 - NCT07499128Enrolling by invitation
Continuous temperature monitoring for cytokine release syndrome
This study tests a wearable device that continuously monitors your body temperature to detect cytokine release syndrome, a possible side effect of certain immunotherapies. The goal is to catch it early so you can get treatment faster.
Bethesda, MarylandAges 18–120 - NCT06434376Enrolling by invitationEarly Phase 1
Personalized immune therapy for ctDNA-positive colorectal cancer
This trial tests a personalized immune therapy (like a custom vaccine) for people with colorectal cancer that has a positive ctDNA MRD test after surgery. It aims to use the body's own immune system to target any remaining cancer cells and prevent the cancer from coming back.
Wenzhou, ZhejiangAges 18–80 - NCT05528796Enrolling by invitation
Finding causes of non-immune fluid buildup in babies
This study looks for the underlying cause of “non-immune hydrops fetalis,” a serious condition where a baby has abnormal fluid buildup. It focuses on families whose usual genetic tests didn’t find an answer (or weren’t completed before birth).
San Francisco, CaliforniaAges 18–60 - NCT03914768Enrolling by invitationPhase 1
Immune Cell Vaccine for Brain Tumors
This trial tests a vaccine made from immune cells (dendritic cells) designed to train your body to fight brain tumors like DIPG or glioblastoma. You may qualify if you have one of these tumors, have had standard treatment, and are generally healthy enough for the study.
Shenzhen, GuangdongAges 1–75 - NCT03393962Enrolling by invitationPhase 1/Phase 2
Antigen-targeted immune cell treatment for high-risk ovarian cancer
This early-phase trial tests a lab-made immune cell treatment designed to recognize ovarian cancer and attack it. It may help people with high-risk ovarian cancer who still need effective options.
Shenzhen, GuangdongAges 10–80 - NCT07775820Recruiting
Retrying immunotherapy after lung inflammation
This trial looks at whether people with lung cancer who had lung inflammation from immunotherapy can safely try immunotherapy again. It aims to see if restarting treatment helps without causing severe side effects.
Guangzhou, GuangdongAges 18 years+ - NCT07775235Recruiting
Treatment outcomes for muscle inflammation with rapid lung disease
This study looks at how well treatments work for people with muscle inflammation (myositis) that causes a fast-progressing lung condition. It may help doctors find better ways to manage this serious combination.
SingaporeAges 21 years+ - NCT06575426RecruitingPhase 1/Phase 2
Pig pancreatic cell transplant for type 1 diabetes
This trial tests a new treatment made from pig pancreatic cells (called OPF-310) that are placed under the skin to help control blood sugar in people with type 1 diabetes. It is for those whose diabetes is difficult to manage and who have dangerous low blood sugar episodes.
Chicago, IllinoisAges 35–70 - NCT07562152RecruitingPhase 3
Atebimetinib Plus Gemcitabine/Nab-Paclitaxel for New Pancreatic Cancer
This trial tests a combination of three drugs—atebimetinib (a new targeted therapy), gemcitabine, and nab-paclitaxel (two standard chemotherapy drugs)—as a first treatment for pancreatic cancer that has spread beyond the pancreas. The goal is to see if adding atebimetinib helps patients live longer and feel better.
Phoenix, ArizonaAges 18 years+ - NCT07698600RecruitingPhase 1
Safety test of a new HIV vaccine in adults with or without HIV
This study tests a new RNA-based vaccine called BNT168 to see if it is safe and how the body responds to it. It is for healthy adults with or without HIV, and those with HIV will pause their regular treatment for a while during the study.
Houston, TexasAges 18–50 - NCT07473154RecruitingPhase 1/Phase 2
Calming an overactive immune system with special cells
This trial tests a new type of cell therapy made from a patient's own white blood cells (called lymphocytes) that are designed to help control the immune system. The goal is to reduce inflammation and symptoms in people with hard-to-treat rheumatoid arthritis or a severe form of scleroderma (dcSSc).
DüsseldorfAges 18 years+ - NCT06225011RecruitingPhase 1
Can a common antidepressant help your immune system fight colorectal cancer before surgery?
This trial is testing whether a common antidepressant called fluoxetine (Prozac) can help your immune system fight colorectal cancer before surgery. It's for people with early-stage colorectal cancer who have not yet had treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT06538961Recruiting
Immune registry for BK virus in kidney transplant patients
This study is creating a registry to learn how the immune system responds to BK virus in people who have recently received a kidney transplant from a deceased donor. Researchers hope this information will help improve treatment for BK virus infections.
Richmond, VirginiaAges 18 years+ - NCT07577505Recruiting
Histidine supplement to boost immunity in colorectal cancer
This study tests whether taking a histidine supplement (an amino acid building block) alongside standard colorectal cancer treatment helps your immune system fight the cancer better. Researchers want to see if this simple addition can improve outcomes for people with stage II or higher colorectal cancer.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07042295RecruitingPhase 2
Amivantamab or Cetuximab for Skin Cancer in People with Weakened Immune Systems
This trial tests two drugs, amivantamab with hyaluronidase or cetuximab, in people with weakened immune systems who have advanced skin cancer (squamous cell carcinoma). The goal is to see if these treatments can help shrink or control the cancer.
Birmingham, AlabamaAges 18 years+ - NCT01386437Recruiting
Study immune problems and fungal infections
This study looks at how immune system problems relate to fungal infections, using medical records and lab tests on blood and tissue. It may help researchers understand the cause of these infections—especially for people with inherited immune conditions—and improve future care.
Bethesda, MarylandAges 1 day–99 years - NCT05335928RecruitingPhase 3
Abatacept for immune-therapy heart inflammation in hospitalized adults
This Phase 3 trial tests abatacept to treat myocarditis (inflammation of the heart muscle) caused by immune checkpoint cancer medicines. It may help patients recover faster and safely manage this serious side effect while they are in the hospital.
Los Angeles, CaliforniaAges 18 years+ - NCT07251179Recruiting
Understanding immune cells in autoimmune diseases and immune deficiencies
This study looks at immune cells in people with certain autoimmune diseases or immune deficiencies. The goal is to understand how these cells work, which may help improve future treatments.
StrasbourgAges 18–70 - NCT07772570Recruiting
Studying blood markers in coronary artery disease
This study collects blood samples and images from patients with heart muscle damage or those undergoing coronary angiography. The goal is to find new biomarkers that could improve diagnosis and treatment of coronary artery disease.
OxfordAges 18–90
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Common questions
- Are there clinical trials for immunity?
- Yes. Clin2 currently lists 1,069 recruiting immunity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immunity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immunity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.