Clinical trials
Infectious Disease clinical trials
Below are recruiting infectious disease clinical trials, each written for real people, not researchers. We’re tracking 254 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01905826Recruiting
Study of GATA2 deficiency causes and health outcomes
This natural history study looks at how GATA2 deficiency (a genetic condition) affects health over time. It may help doctors better understand complications and plan future care, and it includes genetic testing and stored samples.
Bethesda, MarylandAges 2–100 - NCT01011712Recruiting
Study immune causes of severe viral infections
This study looks at why some people have severe or unusual viral infections, even when they do not have a known immune problem. It collects blood and tissue samples to better understand possible inherited immune issues and may help future diagnosis and treatment.
Bethesda, MarylandAges 2–100 - NCT00039689Recruiting
Blood collection study for newly diagnosed HIV research
This research study collects blood cells from people recently diagnosed with HIV who haven't started HIV medicines yet. Researchers use these samples to understand how HIV affects the immune system and develop better treatments.
Bethesda, MarylandAges 18–120 - NCT01375530Recruiting
Volunteers needed for future medical research testing
This trial is looking for adult volunteers who agree to have blood and/or tissue samples collected and stored for later studies. It may help researchers better understand the immune system and future treatments, although it is mainly a sample-storage study rather than a specific drug treatment.
Atlanta, GeorgiaAges 18–60 - NCT00867269Recruiting
Study of causes and progression of low CD4 blood cells
This study looks for what causes and how idiopathic low CD4 cells happen over time, using blood and tissue samples. It may help doctors learn why this occurs and how to better track people with it.
Bethesda, MarylandAges 18 years+ - NCT00090662Recruiting
Healthy Volunteer Sample Collection for Medical Research
This research study collects blood, urine, and other samples from healthy volunteers to support medical research. Depending on the type of sample, you may donate blood, provide skin samples, or participate in other non-invasive procedures. Your samples help scientists understand health and develop new treatments.
Bethesda, MarylandAges 18–85 - NCT01212003Recruiting
Study of how tuberculosis develops over time
This study follows people with suspected or confirmed tuberculosis (TB), whether they have inactive “latent” TB or active TB. It helps researchers better understand TB’s natural course and may improve future testing and care by allowing collection and storage of samples.
Bethesda, MarylandAges 2–100 - NCT01520844Recruiting
HIV cohort study comparing people on and off treatment
This study follows adults with HIV over time to compare different groups based on how stable their virus levels are. It may help researchers understand who can safely interrupt treatment and who should stay on it, and how immune health changes.
Le Kremlin-BicêtreAges 18–85 - NCT01306019RecruitingPhase 1/Phase 2
Gene therapy for children with severe immune deficiency (XSCID)
This trial tests a one-time gene therapy approach to help children with X-linked SCID (a serious inherited immune disorder) make better immune cells. It’s for people who don’t have a fully matched sibling donor and need long-term follow-up after treatment.
Bethesda, MarylandAges 2–50 - NCT02190266Recruiting
Study genetics and cause of hard-to-treat Valley fever
This study looks at why “Valley fever” is difficult to treat or has spread beyond the lungs, and how a person’s genetics may be involved. You may be asked for blood or other samples for genetic testing and for storing samples for future research.
Bethesda, MarylandAges 2–100 - NCT02147405Recruiting
PET scans and lymph node checks for HIV immune rebound
This study looks at people with HIV who either have not started HIV medicines yet or who recently started/changed them and may develop immune rebound (IRIS). It uses blood tests and optional PET/CT scans and lymph node biopsies to understand what’s happening in the body and to guide care.
Bethesda, MarylandAges 18–100 - NCT02639299Recruiting
Screening healthy adults for malaria vaccines and drug studies
This study screens healthy adults to see who can join future malaria vaccine or investigational malaria drug studies, including a controlled malaria exposure. It may help researchers test safer vaccines/drugs, but participation requires good health and strict medical eligibility.
Bethesda, MarylandAges 18–50 - NCT02734277Recruiting
Extending a past Type 1 diabetes immune study
This study is for people who already took part in an earlier immune-tolerance program for Type 1 diabetes. It tests whether continuing follow-up and assessments can be done safely and may help learn more about long-term immune effects of treatment.
San Francisco, CaliforniaAges 8–35 - NCT03109288RecruitingPhase 1/Phase 2
Biomarker-guided combination treatment for residual multiple sclerosis activity
This early-phase study tests combination treatments for multiple sclerosis (MS) based on lab “biomarkers” found in the spinal fluid. It aims to reduce ongoing MS activity and help determine which treatment combinations may work best for different people.
Bethesda, MarylandAges 18–120 - NCT02511002Enrolling by invitation
Long-term follow-up after an influenza challenge study
This study keeps track of how your body’s immune responses change over time after an influenza exposure. Researchers may use stored blood samples to study specific antibody levels, which could help improve future flu vaccines or treatments.
Bethesda, MarylandAges 18–120 - NCT01186913Enrolling by invitation
Natural history study for severe combined immune deficiency (SCID)
This study follows children and adults with SCID and related immune disorders to understand how the illness behaves over time. It also helps researchers learn which testing results and genetic types of SCID match different treatment plans.
Birmingham, AlabamaAges Any age - NCT00895271Enrolling by invitation
Making lab cell lines from skin biopsies in immune disorders
This study creates special lab cell lines from skin (or nasal) samples from people with immune system disorders and certain family members. It’s meant to help researchers build tools to better study these conditions using patient cells.
Bethesda, MarylandAges 2–85 - NCT00004317RecruitingPhase 4
Treating Congenital Toxoplasmosis With Three Medications
This study tests a combination of three medications (pyrimethamine, sulfadiazine, and leucovorin) to treat toxoplasmosis—a parasitic infection passed from mother to baby during pregnancy. The goal is to see if early treatment prevents serious complications in infected infants.
Chicago, IllinoisAges Any age - NCT00001351Enrolling by invitation
Study of inflammatory disorders and immune system dysfunction
This is a long-term study that evaluates and follows patients with inflammatory conditions related to infections or immune system problems. Researchers at the National Institutes of Health want to understand these conditions better and may ask you to participate in related studies.
Bethesda, MarylandAges 2 years+ - NCT07406529Recruiting
Can awe inspire preventive behaviors?
This trial is studying whether feeling a sense of awe can encourage people to take helpful, preventive actions (like handwashing or social distancing). If you live in a big Asian city, you can join by completing a short online survey.
Hong KongAges 18 years+ - NCT07416201Recruiting
Study of Immune System Aging in Down Syndrome
This study is looking at how the immune system changes over time in people with Down syndrome, and how it may be affected by removal of the thymus gland. The goal is to understand why people with Down syndrome may age faster or have different immune health.
Bethesda, MarylandAges 1–120 - NCT07447869RecruitingEarly Phase 1
Lymph Node Exam in Cat Allergy Treatment Study
This study looks at lymph nodes in the neck to understand how the body responds to cat allergy treatments. It may help researchers improve allergy shots or other therapies for people with cat allergies.
Boston, MassachusettsAges 18–45 - NCT07549503RecruitingPhase 2
Liver Transplant Immune Changes Study
This research study tracks early signs of immune system changes in children who received a liver transplant 3–7 years ago and are doing well. By studying blood and liver samples, researchers hope to better understand how to prevent rejection and improve long-term transplant survival.
San Francisco, CaliforniaAges 3–13 - NCT07559318Recruiting
Optimizing Antibiotic Choice for Urinary Tract Infections
This study helps doctors choose the best antibiotic for urinary tract infections (UTIs) by looking at urine culture results. You'll be treated as an outpatient (at home) and monitored to see if your antibiotic is working well.
MelunAges 18 years+
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Common questions
- Are there clinical trials for infectious disease?
- Yes. Clin2 currently lists 254 recruiting infectious disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a infectious disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a infectious disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.