Clinical trials
Injection clinical trials
Below are recruiting injection clinical trials, each written for real people, not researchers. We’re tracking 2,037 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05024344Recruiting
Nerve block to reduce pain after kidney stone surgery
This trial tests whether an “ESP block” (a targeted local anesthetic injection near nerves) works better than standard care to control pain after percutaneous kidney stone removal. If it helps with pain, it could reduce the need for stronger pain medicines after surgery.
Knoxville, TennesseeAges 18 years+ - NCT04957095Recruiting
Testing brain wiring signals during planned deep brain stimulation
This study looks at how brain networks work during a procedure used to treat movement symptoms in Parkinson’s disease. It may help researchers better understand the brain signals involved, which could improve future deep brain stimulation planning.
Dallas, TexasAges 18–89 - NCT04929951RecruitingPhase 1
Micro fat injection to treat shoulder arthritis
This Phase 1 study tests whether a micro-fragmented fat (MFAT) injection can reduce symptoms and improve shoulder function in people with shoulder osteoarthritis. It’s early research, so the goal is mainly to see if the treatment is safe and possibly helpful.
Stanford, CaliforniaAges 25–75 - NCT04999215RecruitingPhase 3
Test whether F-choline PET scans help in new conditions
This study checks how useful an F-choline PET scan is for finding information in people with known or suspected conditions. It may help doctors decide what to look for or how to guide care in “new and emerging” situations.
Montreal, QuebecAges 18 years+ - NCT04930887RecruitingPhase 2
Numbing injection in the face to ease craniofacial pain
This trial tests whether an injection of a numbing medicine (bupivacaine) guided by an endoscope can reduce craniofacial pain. It may help people with certain headache or facial pain conditions by targeting the pain area more precisely.
Stanford, CaliforniaAges 18–80 - NCT04990128RecruitingPhase 3
Bone marrow fluid injection versus steroid shots for hip arthritis
This trial compares a “bone marrow aspirate concentrate” injection with a corticosteroid (steroid) injection to reduce pain from hip osteoarthritis. It aims to see which treatment works better over time for hip pain and function.
Weston, FloridaAges 18–75 - NCT03849443RecruitingEarly Phase 1
Testing tranexamic acid to reduce bleeding after spine fusion
This trial studies whether a single dose or multiple doses of tranexamic acid (TXA) can reduce the chance you need a blood transfusion after spine fusion surgery. It also compares two different ways TXA may be given (by mouth and through a vein) to see which approach works best and is safe.
Chicago, IllinoisAges 18 years+ - NCT04787848Recruiting
Testing pain causes and treatments in people with HIV
This study looks at why chronic widespread pain happens in people with HIV and tests new ways to understand and treat it. You may be able to join if your HIV is stable on treatment and you meet pain and safety requirements.
Miami, FloridaAges 19–65 - NCT04853251RecruitingPhase 4
Study of corneal cells after a ranibizumab eye implant
This trial checks how well corneal endothelial cells (cells that help keep the cornea clear) do in people with neovascular age-related macular degeneration (nAMD) who are treated with a port-delivery implant that releases ranibizumab. It also helps doctors understand whether this method changes corneal health and stays safe while controlling the eye disease.
Mesa, ArizonaAges 50 years+ - NCT04686097Recruiting
Comparing two treatments for leg vein problems
This trial compares a needle-based procedure (electrocoagulation) with a foam injection (sclerosing foam) to treat faulty veins in the legs that cause skin damage or ulcers. It aims to find which method works better for people with moderate to severe vein disease.
Hefei, AnhuiAges 18–80 - NCT04706910RecruitingPhase 3
PET scan study to optimize imaging in several diseases
This trial improves a special PET scan (a type of brain/body imaging) using 18F-DOPA, to better show how certain conditions behave in the body. If you or your child may have one of the listed conditions, the study may help your doctors get clearer scan results.
Edmonton, AlbertaAges Any age - NCT04732507Enrolling by invitationPhase 2
Trigger point injections: test fewer needlings for pain relief
This Phase 2 study tests whether doing a smaller number of needle “treatments” during trigger point injections works as well for myofascial pain. If you’ve tried safer treatments without success (or can’t do physical therapy), you may be eligible to help answer the best treatment approach.
Tucson, ArizonaAges 18 years+ - NCT04695600RecruitingPhase 2/Phase 3
Botox for swallowing problems after brain injury
This trial tests if Botox injections in the throat can help people who have trouble swallowing due to a brain condition like stroke. It aims to improve safety and ease of eating and drinking.
New Delhi, National Capital Territory of DelhiAges 14 years+ - NCT04752826RecruitingPhase 1/Phase 2
A new drug combo for advanced cancers
This trial tests a new experimental drug, BI-1808, alone or with an approved cancer drug called pembrolizumab (Keytruda). It's for people with advanced cancers that have stopped responding to standard treatments.
Duarte, CaliforniaAges 18 years+ - NCT04729114RecruitingPhase 1
Safety and dose test of PRL-02 shot for advanced prostate cancer
This Phase 1 study tests how safe PRL-02 depot (an injection) is and finds the best dose for men with advanced prostate cancer. It may help determine a new treatment option for cancers that have spread or are getting worse despite standard care.
Tucson, ArizonaAges 18 years+ - NCT04638647RecruitingPhase 4
Continue secukinumab after prior study, without safety issues
This trial lets people who already did a previous secukinumab (an injection for certain inflammatory conditions) study continue treatment afterward. It’s mainly for people who are still getting benefit and can’t otherwise get the approved medication through their local system.
Fullerton, CaliforniaAges 6–100 - NCT04608630RecruitingPhase 2
Preventing bone loss in ICU patients with anti-bone drugs
This Phase 2 study tests whether zoledronic acid or denosumab can prevent bone thinning in critically ill adults after staying in the ICU. It may help reduce the risk of future bone fractures if your body is at higher risk during and after critical illness.
Sydney, New South WalesAges 50 years+ - NCT04519619Recruiting
Safety study of aflibercept eye injections in Japanese glaucoma patients
This trial checks how safe aflibercept (eye injection) is for Japanese people with neovascular glaucoma. You may be able to join if you already received aflibercept treatment under the approved Japanese instructions and have the correct diagnosis.
Multiple LocationsAges Any age - NCT04547348RecruitingPhase 3
Denosumab for healing an acute Charcot foot in diabetes
This Phase 3 trial tests whether denosumab can improve healing and outcomes for people with an acute Charcot foot caused by diabetes-related nerve problems. You may be able to join if your Charcot foot is recently diagnosed and you meet specific safety and lab requirements.
AalborgAges 18–80 - NCT04575688Enrolling by invitationPhase 4
Nerve-block injection options for ankle or heel surgery
This trial compares two methods of numbing pain—an injection near the joint versus a nerve block—during ankle or hindfoot surgery. It aims to see which approach helps with comfort and recovery after surgery.
Germantown, TennesseeAges 18–80 - NCT04478292RecruitingPhase 3
New treatment strategy for children with newly diagnosed liver cancer
This Phase 3 study tests a modified treatment plan for children newly diagnosed with hepatoblastoma, a type of liver cancer. It may help improve how well treatment works and how safely it can be given by using a structured approach.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT04180085RecruitingPhase 2
Belatacept to protect kidneys in heart transplant patients
This trial studies whether belatacept can be used after a heart transplant to help protect kidney function over time. It focuses on people who already have (or are at risk for) worsening kidney function after transplant, while avoiding those with certain infections or rejection concerns.
BordeauxAges 18 years+ - NCT04291755Enrolling by invitation
Stool bank for people receiving cancer immunotherapy
This study is building a “stool bank,” meaning they collect and store stool samples from people who are getting cancer immunotherapy. Researchers plan to analyze these samples to better understand cancer and treatment—your participation may help future research.
Fountain Valley, CaliforniaAges 18 years+ - NCT04265872RecruitingEarly Phase 1
Bortezomib then pembrolizumab and cisplatin for metastatic triple-negative breast cancer
This early-phase trial tests a new treatment plan for people with metastatic triple-negative breast cancer that has already been treated with standard chemotherapy. It aims to see how well the combination works and whether it’s safe.
Dallas, TexasAges 18 years+
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Common questions
- Are there clinical trials for injection?
- Yes. Clin2 currently lists 2,037 recruiting injection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a injection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a injection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.