Clinical trials
Insomnia clinical trials
Below are recruiting insomnia clinical trials, each written for real people, not researchers. We’re tracking 255 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06981195RecruitingPhase 2
Testing lemborexant for insomnia in people on buprenorphine
This study tests if the sleep medication lemborexant can help people with opioid use disorder who also have chronic insomnia. Participants must already be taking buprenorphine (Suboxone) for at least 4 weeks. The goal is to see if better sleep improves mood and reduces opioid use.
Richmond, VirginiaAges 18 years+ - NCT06953869RecruitingPhase 3
Testing a sleep medicine for children with insomnia
This study tests if the drug tasimelteon helps children with insomnia sleep better compared to a placebo (a pill with no medicine). It is for children aged 2 to 17 who have been diagnosed with insomnia that is not caused by another medicine.
Dothan, AlabamaAges 2–17 - NCT06931236Enrolling by invitation
Brain stimulation for anxiety and insomnia
This study tests whether a noninvasive brain stimulation technique called rTMS can help people with both anxiety and insomnia. Treatments target a specific brain region to reduce anxiety and improve sleep.
Hefei, AnhuiAges 15–65 - NCT06898099Recruiting
Hypnotherapy for chronic insomnia in primary care
This study tests whether 4 short hypnotherapy sessions can help people with chronic insomnia. It is designed for adults who struggle with sleep for months and want a non-drug option in their regular doctor's office.
Bain-de-BretagneAges 18 years+ - NCT06897007Recruiting
Ciprofol dosage in patients with insomnia under anesthesia
This study looks at how the sedative drug ciprofol works differently in people with insomnia compared to those who sleep well. It aims to help doctors give the right dose for your type of surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT06156306Recruiting
Comparing two sleep and anxiety therapies for young people
This study compares two types of talk therapy to help young people who struggle with both insomnia and anxiety. Both treatments involve learning skills to improve sleep and manage anxious thoughts; one version also includes strategies for accepting difficult emotions.
Shatin, New TerritoriesAges 15–24 - NCT06823752RecruitingPhase 2
Insomnia medication to reduce brain damage markers in adults
This trial tests whether a medication that blocks brain chemicals involved in wakefulness can help reduce markers of nerve damage in people with insomnia. It is for adults aged 40–65 with chronic insomnia, and it aims to see if improving sleep may protect brain health.
Macquarie Park, New South WalesAges 40–65 - NCT06802913RecruitingEarly Phase 1
Inhaled melatonin for sleep problems in older adults
This trial tests a new inhaled form of melatonin to help adults aged 55 and older with insomnia fall asleep faster. It compares the inhaled melatonin to a placebo to see if it improves sleep and is safe.
Macquarie Park, New South WalesAges 55 years+ - NCT06736548Enrolling by invitation
Sleep treatment program for cancer survivors
This study tests a sleep education program for cancer survivors who have trouble sleeping. You will learn strategies to improve your sleep and overall well-being.
Boston, MassachusettsAges 18–89 - NCT06736444Recruiting
Sleep and Substance Use Help for Young Adults
This study tests a brief program to help young adults who struggle with sleep and also use alcohol or cannabis. The program teaches skills to improve sleep quality and reduce risky substance use.
Seattle, WashingtonAges 18–29 - NCT06694441Recruiting
Sleep, brain chemicals, and memory in older adults with insomnia
This study looks at how a brain chemical called norepinephrine affects sleep and thinking in older adults with insomnia. You may join if you are 55+, have insomnia, and are generally healthy.
Chicago, IllinoisAges 55 years+ - NCT06671457Recruiting
Brain stimulation study for insomnia
This trial tests a personalized, non-invasive brain stimulation method (transcranial direct current stimulation, or tDCS) to improve sleep in adults with insomnia. It may help if you have trouble sleeping and haven't tried certain other treatments.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06669507Recruiting
Sleep clinic study on non-drug treatment options
This study looks at how people with certain sleep disorders respond to non-medication treatments. If you have trouble with your sleep-wake cycle and would like behavioral or lifestyle help instead of drugs, this trial might be for you.
TrondheimAges 18 years+ - NCT06655883RecruitingPhase 3
Testing suvorexant for insomnia in people with opioid use disorder
This study tests whether the sleep medication suvorexant (Belsomra) can help people with opioid use disorder who also have trouble sleeping. If you are stable on medication for opioid use disorder and have not used opioids in the last month, this trial may be an option for you.
Garden Grove, CaliforniaAges 18–70 - NCT06656533Recruiting
Timing of brain stimulation to improve insomnia treatment
This study tests whether giving a specific type of brain stimulation (rTMS) at the right time can help make insomnia treatment work better. It may be an option for people ages 25 to 45 who have trouble sleeping and live near Stanford University.
Palo Alto, CaliforniaAges 25–45 - NCT06638450Recruiting
Acupuncture for Teens with Stress and Insomnia
This study tests whether acupuncture can help teenagers who have been feeling anxious or down and having trouble sleeping. If you've had these feelings for more than 3 months and haven't taken medicine or had acupuncture recently, you may be able to join.
Hong Kong, Hong KongAges 15–22 - NCT06567210Recruiting
Insomnia treatment and emotional memory regulation for mental health
This study tests whether treating insomnia can help regulate emotional memories overnight, which may reduce the risk of developing or worsening mental health conditions. You may be eligible if you have both insomnia and some anxiety symptoms.
Macquarie Park, New South WalesAges 18–45 - NCT06511011RecruitingPhase 2
Chinese Herbal Medicine for Chronic Insomnia
This trial tests a Chinese medicine treatment for people with long-term insomnia that is caused by a specific imbalance (Yin deficiency with internal heat). It aims to see if the herbal formula can improve sleep quality and daily function.
ShatinAges 18–65 - NCT06497894RecruitingPhase 4
Hormone therapy for sleep in late menopause
This trial tests whether hormone replacement therapy (HRT) can improve sleep for women in late menopause who have insomnia. If you are in late menopause and struggle with poor sleep, this study may offer a treatment option.
BernAges 45–69 - NCT06478628Enrolling by invitation
Insomnia in pain rehabilitation patients
This trial looks at sleep problems in people going through pain rehabilitation. It aims to understand and possibly improve sleep in those with long-lasting pain.
RissaAges 18 years+ - NCT06373718Recruiting
How sleep affects emotions in insomnia with low mood
This study explores how improving sleep might help regulate emotions in people who have both insomnia and mild depressive symptoms. You could help researchers understand the link between sleep and mood.
Palo Alto, CaliforniaAges 18–65 - NCT06375265Recruiting
Sleep improvement program for older surgery patients
This trial tests a digital sleep improvement program for older adults who are about to have knee or hip replacement surgery. It aims to help you sleep better before and after surgery, which may improve your brain health and recovery.
Boston, MassachusettsAges 65 years+ - NCT06376760Recruiting
Anesthetic dose changes for insomnia patients during endoscopy
This study looks at how insomnia affects the amount of anesthesia needed during a digestive endoscopy. It compares people with insomnia to those with normal sleep to see if dosage adjustments are needed.
Beijing, Beijing MunicipalityAges 18–64 - NCT06286774Recruiting
Sleep and alcohol treatment study
This study tests whether improving sleep through cognitive behavioral therapy (CBT-I) can help reduce heavy drinking in people with both alcohol use disorder and insomnia. It might be a good fit if you have trouble sleeping and drink heavily.
Columbia, MissouriAges 18–49
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Common questions
- Are there clinical trials for insomnia?
- Yes. Clin2 currently lists 255 recruiting insomnia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a insomnia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a insomnia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.