Clinical trials
Joint Pain clinical trials
Below are recruiting joint pain clinical trials, each written for real people, not researchers. We’re tracking 82 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07325513Recruiting
Brain stimulation for Gulf War-related pain
This study tests whether a type of brain stimulation (repeated transcranial magnetic stimulation, or rTMS) can help reduce headaches and body pain in veterans with Gulf War Illness. If you are a Gulf War veteran with ongoing moderate-to-severe pain, this trial could help find a new way to manage your symptoms.
San Diego, CaliforniaAges 18–65 - NCT06965452Recruiting
Embolization for back pain from worn-out facet joints
This study tests if a minimally invasive procedure, called trans-arterial embolization, can reduce low back pain caused by aging facet joints (facet arthropathy). It may help people who haven't found relief from other treatments like injections or nerve blocks.
Manhasset, New YorkAges 18–85 - NCT07321483Recruiting
Reflex therapy for jaw pain
This trial tests if a special reflex therapy can help people with jaw muscle pain that isn't caused by joint damage. It might be a new way to reduce discomfort and improve function.
OlomoucAges 18 years+ - NCT06686147Recruiting
AI analysis of movement in low back pain
This trial uses artificial intelligence to analyze how well you can move if you have chronic low back pain. It may help researchers understand movement patterns better.
DenizliAges 18–65 - NCT06728579RecruitingPhase 2
Group therapy for joint pain in breast cancer survivors
This study tests two supportive group programs—one using mindfulness skills, the other providing supportive talk therapy—to help breast cancer survivors manage joint pain caused by hormone-blocking pills. If you have ongoing joint pain and are taking an aromatase inhibitor, you may be able to join a free, video-based group.
San Diego, CaliforniaAges 18 years+ - NCT05501210Recruiting
Knee vibration therapy for ongoing front-of-knee pain after ACL surgery
This trial studies whether a vibrating device on the front of the knee can reduce persistent pain after ACL reconstruction. It may help people whose pain is focused in one knee and isn’t caused by arthritis or other knee problems.
Hong KongAges 18–60 - NCT06658821Enrolling by invitation
Study of LDL557 for knee arthritis in older adults
This trial tests whether a supplement called LDL557 can improve early-stage knee arthritis in people over 65. It aims to reduce pain and slow joint damage.
TaichungAges 45–80 - NCT07558278RecruitingPhase 4
LINQ procedure vs standard care for sacroiliac joint pain
This study compares a new procedure called LINQ—which stabilizes the sacroiliac joint (the joint where your spine connects to your pelvis)—against standard pain management for chronic sacroiliac joint pain. The trial tests whether this procedure reduces pain and disability better than medications and physical therapy alone.
Shenandoah, TexasAges 21 years+ - NCT07740967Recruiting
Collagen and omega supplements for middle-aged women
This study tests whether daily collagen and omega-3 supplements can improve health in healthy middle-aged women. You would take the supplements for a period and have your health measured.
LoughboroughAges 35–65 - NCT07729930Recruiting
Creatine supplement study for healthy middle-aged women
This study is testing a creatine supplement (a substance that may help with energy and muscle function) in healthy middle-aged women. You may join if you are between 35 and 65, a non-smoker, and have a certain activity level.
LoughboroughAges 35–65 - NCT05658575RecruitingPhase 2/Phase 3
Tablets to treat sudden gout flare pain
This trial studies dapansutrile tablets (OLT1177) to see how well they work for people in the first 4 days of an acute gout flare. It may help reduce pain and inflammation in the specific joint where your gout is flaring.
Birmingham, AlabamaAges 18 years+ - NCT06123286RecruitingEarly Phase 1
Tart cherry and omega-3s for joint pain from hormone therapy
This study tests whether taking tart cherry and omega-3 supplements can help reduce joint pain and stiffness caused by aromatase inhibitors (a common breast cancer treatment). If you have bothersome joint pain while on this hormone therapy, you may be able to join.
Los Angeles, CaliforniaAges 18 years+ - NCT06530459RecruitingPhase 2/Phase 3
The MUSE Study for Menopausal Joint Pain
This study tests whether a treatment can help women with joint pain and stiffness that started or worsened during menopause. It focuses on women who are within 5 years of menopause and have pain in multiple joints.
SingaporeAges 30–59 - NCT06541119Recruiting
Strengthening a leg muscle for bunion pain and function
This study tests whether strengthening a specific muscle on the outside of your lower leg can help reduce pain, improve foot alignment, and make it easier to walk and do daily activities if you have a bunion (hallux valgus).
GizaAges 18–60 - NCT06814977Recruiting
Acupuncture for joint pain in cancer survivors
This study tests whether acupuncture can help reduce joint pain in cancer survivors. If you have bothersome joint pain that has lasted at least a month, acupuncture might offer relief.
New York, New YorkAges 18 years+ - NCT06863636RecruitingPhase 3
Combination painkiller vs celecoxib for osteoarthritis flare-ups
This study tests whether a combination of two pain relievers (celecoxib and acetaminophen) works better than celecoxib alone for sudden, severe osteoarthritis pain in the knee or hip.
Mexico CityAges 40 years+ - NCT06859697Enrolling by invitation
Herbal medicine for obesity with spine or joint pain
This trial tests whether herbal medicine can safely help with pain and weight loss in people who have both obesity (BMI 25 or higher) and back or joint pain. It aims to see if the treatment works and is safe.
Seoul, Gangnam-GuAges 19–69 - NCT07474662Recruiting
Online vs. in-person physiotherapy for jaw muscle pain
This trial compares online physiotherapy sessions with face-to-face visits to see which works better for treating jaw muscle pain (myalgia). It aims to find a more convenient way to get care for this common condition.
Budapest, Pest CountyAges 18 years+ - NCT05272488Recruiting
Manual therapy plus vagus nerve stimulation for jaw muscle pain
This trial tests whether combining hands-on jaw treatment with a vagus nerve stimulator can reduce jaw muscle pain and improve jaw movement. It may help people whose jaw pain has been present recently and who have not had recent physiotherapy.
Alcalá de Henares, MadridAges 18 years+ - NCT05818774Recruiting
Different types of neck nerve ablation for chronic pain relief
This trial compares two ways of using radiofrequency heat to treat a specific set of neck pain nerves (the “cervical medial branch nerves”). It may help people with long-lasting neck pain who did not improve with standard treatments and who respond to diagnostic nerve blocks.
Toronto, OntarioAges 18–85 - NCT06666621RecruitingPhase 4
Naloxone injection for low back pain
This trial tests whether naloxone, a drug that blocks opioid effects, can change how your body responds to pain injections in the lower back. It may help find new ways to treat low back pain that hasn't improved with physical therapy or oral medications.
Nashville, TennesseeAges 18 years+ - NCT06920459Recruiting
Zimmer Biomet Shoulder Replacement Study
This study is testing a shoulder replacement system made by Zimmer Biomet to see how well it works for people with severe shoulder problems, like arthritis or fractures. If you qualify, you would receive the implant and be asked to come back for regular checkups to track your recovery.
PforzheimAges 20 years+ - NCT07348627RecruitingPhase 3
Opioid-free hip replacement study
This trial tests if using fewer opioids after hip replacement surgery can still control pain well. It uses a specific type of hip replacement called anterior total hip arthroplasty and aims to help patients recover with less reliance on strong pain medicines.
Atlanta, GeorgiaAges 18 years+ - NCT07526012Recruiting
Stretching techniques for buttock pain from pinched nerve
This study compares two stretching methods to treat piriformis syndrome, a condition where a muscle in your buttock pinches a nerve. The trial tests whether one stretching approach works better than the other for reducing pain.
Islamabad, Punjab ProvinceAges 20–55
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Common questions
- Are there clinical trials for joint pain?
- Yes. Clin2 currently lists 82 recruiting joint pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a joint pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a joint pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.