Clinical trials
Kidney Failure clinical trials
Below are recruiting kidney failure clinical trials, each written for real people, not researchers. We’re tracking 118 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03627013RecruitingPhase 3
Compare two transplant fluid solutions for kidney, liver, pancreas
This Phase 3 study compares two types of transplant fluid (Custodiol-N vs Custodiol) to protect organs while they are stored before surgery. It may help by reducing damage to the kidney, liver, or pancreas during transplant preparation.
GrazAges 18 years+ - NCT04128189RecruitingPhase 3
Shingrix vaccine for people waiting for a kidney transplant
This Phase 3 study tests whether the shingles vaccine Shingrix is safe and effective for adults with chronic kidney failure who are on the transplant waiting list. It aims to protect you from shingles while you may be dealing with transplant-related immune changes.
Aurora, ColoradoAges 18–70 - NCT04334707Recruiting
Study kidney damage in people with long-term diabetes
This study is looking at different kidney health patterns in people with diabetes, especially diabetic kidney disease and people who have not developed kidney damage despite long-term diabetes. It may help researchers understand why kidney problems happen—and what protective factors might prevent them.
Tucson, ArizonaAges 18 years+ - NCT06343727Recruiting
Egg White Pudding for Low Protein in Kidney Dialysis
This trial tests whether eating a special high-protein egg white pudding every day for 12 weeks can help people on dialysis with low protein levels. It's for adults with chronic kidney disease who are on center-based hemodialysis and have a low blood protein level called albumin.
Winnipeg, ManitobaAges 18 years+ - NCT06981585Recruiting
Physical effects in children with chronic kidney failure
This study looks at physical changes in children with chronic kidney failure compared to healthy children. If you join, you will have some physical measurements taken to help doctors understand how kidney disease affects the body.
IzmirAges 8–18 - NCT07446296Recruiting
Kidney transplant exercise program for older adults
This trial tests whether a special exercise program can help people on the kidney transplant waiting list get stronger and improve their health. You would use an app to follow exercise routines at home and check in with the research team.
Philadelphia, PennsylvaniaAges 60 years+ - NCT05374291Enrolling by invitationPhase 3
Dapagliflozin trial for kidney and heart outcomes in severe CKD
This study tests whether dapagliflozin can improve kidney and heart-related outcomes in people with severe chronic kidney disease (CKD). You would take the study medicine (or a comparison treatment) and be followed to see how your kidneys and heart do over time.
Canberra, Australian Capital TeritoryAges 18 years+ - NCT05285878Enrolling by invitationPhase 2
Fingolimod to protect kidney function after kidney transplant
This trial tests whether fingolimod can reduce kidney scarring and preserve kidney function after a new kidney transplant. It focuses on people who are in the early period after transplant who may be at risk for scarring in the kidney.
Houston, TexasAges 18–65 - NCT06056102RecruitingPhase 1
CAR-T cell therapy to help highly sensitized kidney transplant patients
This trial tests whether a special immune cell treatment (CAR-T cells) can lower the antibodies that make it very hard for you to receive a kidney transplant. If it works, you might become eligible for a transplant sooner.
Boston, MassachusettsAges 18–65 - NCT07053462RecruitingPhase 1/Phase 2
Gene-edited kidney transplant to lower rejection risk
This trial tests a specially edited donor kidney designed to reduce the chance of rejection, especially for people with high sensitivity to donor kidneys. If it works, it could make more kidneys available for those who have a hard time finding a match.
Beijing, ChangpingAges 16–85 - NCT07341516Enrolling by invitation
Global study of deceased donor kidney use
This study examines all kidneys donated from deceased donors (brain death or circulatory death) between 2010 and 2025 to understand how they are used for transplantation. It may help improve future transplant practices.
Nashville, TennesseeAges Any age - NCT05788276RecruitingPhase 4
Dapagliflozin to help transplanted kidneys stay healthy
This study tests whether dapagliflozin can preserve the structure and function of a kidney transplant. You may be asked to take dapagliflozin on top of usual transplant medicines to see if it helps the new kidney work better over time.
Oslo, OsloAges 18–75 - NCT06243731Recruiting
Maribavir for CMV after transplant in kidney failure
This study looks at how well the drug maribavir works in adults with kidney failure who get a CMV infection after a transplant. It focuses on people whose CMV infection hasn't responded to other treatments.
Anderlecht, Brussels CapitalAges 18 years+ - NCT05613010Recruiting
Tech tools to help young transplant patients take meds correctly
This study tests technology (like text reminders and an electronic pill box) to help adolescents and young adults who received a kidney or liver transplant take their medicines every day. It may help protect the transplant by improving medication adherence.
Baltimore, MarylandAges 13–25 - NCT06307652RecruitingPhase 3
Testing a new heart failure and kidney treatment combo
This study tests a new combination of two medicines (balcinrenone and dapagliflozin) for people with heart failure and reduced kidney function. The goal is to see if this combination helps improve heart and kidney health better than current treatments.
Alexander City, AlabamaAges 18–130 - NCT03310905Recruiting
Abdominal wall transplant for people needing multi-organ transplant
This study evaluates an abdominal wall transplant (replacing the front belly/tissue) done along with another organ transplant. It may help people who need a specialized transplant approach, but it’s only for certain candidates at Duke who meet strict safety and cancer, pregnancy, and anesthesia requirements.
Durham, North CarolinaAges 18–65 - NCT07309367Recruiting
Web-based advance care planning for dialysis patients
This trial tests a web-based program called 'My Voice' that helps people on dialysis plan ahead for their future care. It's for patients in Singapore who have advanced kidney failure and certain health challenges, and it also involves a family caregiver.
SingaporeAges 21 years+ - NCT07607197RecruitingPhase 1/Phase 2
Immune Reset to Help Highly Sensitized Kidney Transplant Patients
This study tests whether a special immune-resetting treatment can help patients who have developed too many antibodies against donor kidneys get access to a compatible kidney transplant. The treatment uses chemotherapy and stem cell transplantation to 'reset' your immune system so it stops rejecting potential donor kidneys.
Barcelona, CataloniaAges 18–60 - NCT06025240Recruiting
Better antibody monitoring after kidney transplant
This study tests a new way to monitor harmful antibodies after a kidney transplant. It may help prevent transplant rejection over time.
Liverpool, MerseysideAges 18 years+ - NCT06006819Recruiting
Acute heart failure with chronic kidney disease study
This trial studies how certain markers in the blood can predict outcomes in people with acute heart failure who also have chronic kidney disease. If you qualify, researchers will follow your health during this hospital stay.
Taipei, Baitou DistrictAges 20–90 - NCT07792317Recruiting
Cold storage treatment for donated kidneys before transplant
This study tests a special cold storage solution and machine to keep donated kidneys healthy before they are transplanted. It may help the kidneys work better after surgery.
RotterdamAges 18 years+ - NCT06314503Recruiting
Safety study of a new peritoneal dialysis device for kidney patients
This trial tests a new device called WEAKID for people on peritoneal dialysis. It aims to see if the device is safe to use. Participants must have been on PD for at least 3 months and have no recent infections or catheter problems.
Modena, ModenaAges 18 years+ - NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT04447911RecruitingPhase 4
Empagliflozin for chronic low blood sodium in certain fluid states
This trial studies whether empagliflozin, a blood-sugar–related medicine, can safely improve chronic low blood sodium when you are not too “dry” or have an imbalanced fluid state. It may help stabilize sodium levels and related health symptoms, but you must meet specific blood and organ-function criteria.
WürzburgAges 18 years+
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Kidney Failure trials by city
Studies with a site in or near these metro areas.
Kidney Failure trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for kidney failure?
- Yes. Clin2 currently lists 118 recruiting kidney failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a kidney failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a kidney failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.