Lifestyle Intervention clinical trials

Virtual Fitness and Health Program for Heart Health

This study tests a virtual fitness program delivered through Peloton and wearable fitness trackers to help adults improve their heart health and fitness. You'll exercise from home, track your progress with a device you already own, and provide blood samples to measure your health improvements.

Lifestyle coaching to support depression care in primary clinics

This trial studies whether motivational, multi-part lifestyle coaching can help adults with depression when they start treatment through a regular primary care clinic. If you’re eligible, the program may add supportive skills to help improve mood alongside usual care.

Lifestyle app for depression with GP support

This trial tests a lifestyle app to help people with depression who are under a GP's care. It looks at whether using the app alongside your usual treatment can improve your mood.

Weight loss trial: endoscopy procedure vs lifestyle changes

This study compares a new endoscopic procedure (a stomach tightening treatment done through a tube in your mouth) with a structured diet and exercise program to help with weight loss. It is for Asian adults who have tried and failed to lose weight before.

SGLT2 inhibitor for prediabetes complications

This trial tests if a drug called dapagliflozin (an SGLT2 inhibitor) can help prevent complications in people with prediabetes when added to lifestyle changes. It aims to see if this approach works better than lifestyle changes alone.

Lifestyle program for back pain and weight

This trial tests a combined exercise and lifestyle program for people with long-lasting low back pain who are overweight or have obesity. The program is delivered by physical therapists and aims to improve physical function and reduce pain.

Grocery delivery plus lifestyle program for high blood pressure and diabetes

This study tests whether a program that delivers healthy groceries along with lifestyle coaching can help people with high blood pressure and type 2 diabetes manage their conditions better. If you qualify, you'll receive support to improve your eating habits and health.

Effectiveness of a Low-Calorie Diet Combined With Intensive Lifestyle Intervention Using Integrated Personalized Diabetes Management for Achieving Diabetes Remission in Patients With Type 2 Diabetes Mellitus

Lifestyle support program for hospital patients

This trial tests a proactive lifestyle program for patients admitted to the hospital. It aims to help you improve your health habits during your stay.

Lifestyle changes to lower dementia risk for older adults

This research study tests whether a program of healthy eating, exercise, and other lifestyle changes can lower your risk for dementia. It is designed for people aged 65–75 with a family history of dementia who want to take steps to keep their brain healthy.

Lifestyle change and medication for metabolic syndrome

This trial tests a lifestyle program combined with two medications (semaglutide and dapagliflozin) to help people with metabolic syndrome lose weight and improve their health. It may be an option if you are an adult with a BMI of 27 to 45 and have metabolic syndrome.

Study cells in fat tissue and aging cells in older adults

This study uses a special lab test on tiny samples from body fat to map different cell types and “senescent” (aging) cells. It may help researchers understand how aging and obesity are linked, which could guide future treatments.

Reducing obesity with a buddy program

This study explores whether having a friend or family member join you in a weight-loss program helps reduce obesity. You and your buddy will use a food-tracking app and get support from the program.

Lifestyle trial to prevent frailty and aging-related diseases

This study tests whether a lifestyle intervention can help prevent frailty and age-related health problems. If you are between 60 and 90 years old, have some signs of frailty, and can use a mobile app with help, you may be able to join.

Can a mobile app help you live healthier?

This trial tests a smartphone app called WARIFA that gives personalized advice to help prevent chronic diseases and manage diabetes. It is for healthy people or those with one chronic condition, and also for people with type 1 diabetes who use insulin and a continuous glucose monitor.

Music and nature visuals for emotional well-being

This study tests if listening to enhanced music and watching natural visuals can improve your emotional health. You'll use your own headphones and a smartphone or tablet to take part.

Online lifestyle program to lower common health risk factors

This trial tests an internet-based coaching program to help people with lifestyle-related risk factors (like high blood pressure, diabetes risk, smoking, or fatty liver) improve their health. It may help you better manage risk factors that can lead to heart and other long-term diseases.

Preventing foot ulcers with a lifestyle program

This trial tests whether a lifestyle program can help people with diabetes avoid new foot ulcers. If you've healed from a foot ulcer in the last year, you may be able to join.

Healthy lifestyle program for lung disease patients

This trial tests a program that helps people with pneumoconiosis (a lung disease from dust exposure) build healthy habits. It may provide support to improve your quality of life.

Physical activity study for teens with congenital heart disease

This study looks at how teens and young adults with moderate to complex congenital heart disease can improve their physical activity. You might be eligible if you're between 15 and 25, have a heart condition, and get care at Nationwide Children's Hospital or Ohio State University.

Study on how the brain handles uncertainty

This study uses brain imaging to understand how people react to uncertain situations. It may help develop better ways to treat anxiety and related conditions.

Nutrition support program for adults with type 2 diabetes

This trial tests whether improving access to healthy food can help adults with type 2 diabetes—especially people dealing with food insecurity. It also includes a family member who helps support healthy eating at home.

Healthy lifestyle program for new mothers in WIC clinics

This trial tests a lifestyle program for new mothers (up to 1 year after giving birth) who have obesity or had gestational diabetes. It runs in WIC clinics and aims to help you improve your health after pregnancy.

Improving heart health in prostate cancer patients on hormone therapy

This study tests whether combining a time-restricted eating plan, a heart-healthy diet, and a weight-loss medication (GLP-1 receptor agonist) can help improve heart health and weight in men with prostate cancer who are receiving hormone therapy. It aims to reduce the risk of heart problems caused by hormone treatment.