Clinical trials
Liver Ablation clinical trials
Below are recruiting liver ablation clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05361551Recruiting
Test-guided liver ablation for up to five colorectal metastases
This study tests a planning and confirmation software tool during a needle-based liver procedure to treat colorectal cancer metastases. It aims to help doctors cover tumors more completely while reducing the chance of leaving tumor tissue behind.
Houston, TexasAges 18 years+ - NCT07211763Recruiting
Comparing carbon dioxide checks during jet ventilation for liver tumor ablation
This study looks at two ways of measuring carbon dioxide levels during a special type of breathing support called jet ventilation. The goal is to see if less invasive checks work as well as standard ones for people having a procedure to treat liver tumors with heat (radiofrequency ablation).
GothenburgAges 18 years+ - NCT07226869Recruiting
Computer-guided microwave ablation for liver cancer
This study tests a computer-guided microwave ablation procedure to destroy liver tumors. If you have early-stage liver cancer with up to 5 tumors, and one is 2-5 cm in size, you may be a candidate.
Boston, MassachusettsAges 18–90 - NCT07385521Recruiting
AI to predict cancer return after liver surgery
This trial uses artificial intelligence to predict whether colorectal cancer that spread to the liver will come back after surgery. It may help doctors better understand your risk and plan follow-up care.
MilanAges 18 years+ - NCT07459309Recruiting
Combination treatment for liver cancer for people who can't have surgery
This trial tests a new combination treatment that uses heat (ablation) and other therapies to destroy liver tumors. It's for people who cannot have surgery or choose not to, and whose tumor is a specific size.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05265169Recruiting
Tested microwave ablation to treat liver metastases from colon cancer
This study tests whether a specific heating treatment (microwave ablation) can completely destroy small colon cancer spots in the liver. It may help patients who have limited liver tumors and need a precise, minimally invasive option.
Miami, FloridaAges 18 years+ - NCT06179602Recruiting
Study of thermal ablation for liver tumors
This study follows patients who are having a procedure called thermal ablation to treat liver tumors. It aims to learn more about how well the procedure works and how safe it is.
LeidenAges 18–110 - NCT06462742Recruiting
Microwave ablation vs. surgery for intrahepatic cholangiocarcinoma
This trial compares two treatments for a liver cancer called intrahepatic cholangiocarcinoma—surgery to remove the tumor versus microwave ablation, which uses heat to destroy cancer cells. It tests if ablation works as well as surgery for people with small tumors that haven't spread.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07607873Recruiting
Transplant vs surgery after chemo for liver-only colorectal cancer
This trial compares liver transplant versus liver surgery for people whose colorectal cancer has spread only to the liver and cannot be removed initially. You would first receive chemotherapy to shrink the tumors, and if they become removable, you may be randomly assigned to have a liver transplant or standard liver surgery.
MilanAges 18 years+ - NCT06689670Recruiting
Liver tumor ablation with a needle-based device
This trial tests a needle-based device that uses heat or cold to destroy liver tumors. It is for people with primary or secondary liver cancer who cannot have surgery or a transplant.
Topkapı, IstanbulAges 18–100 - NCT06766643RecruitingPhase 2
Stereotactic radiosurgery vs. radiofrequency ablation for liver cancer
This study compares two nonsurgical procedures for liver cancer: stereotactic radiosurgery (focused radiation) and radiofrequency ablation (heat therapy). It is for people whose tumor is in a tricky spot near major blood vessels or other structures, making surgery difficult, and who have not received prior treatment.
TianjinAges 18–75 - NCT04143516RecruitingPhase 2/Phase 3
Test tissue testing right after liver tumor ablation
This study looks at liver metastases treated with a procedure that destroys tumors (ablation) and then checks tumor tissue right away. The team wants to see whether the tissue results can guide immediate retreatment to better control cancer in the liver.
New York, New YorkAges 18 years+ - NCT05444478Recruiting
Microwave ablation plus lenvatinib for recurrent liver cancer
This trial tests whether combining heat treatment to kill liver tumors (microwave ablation) with the medicine lenvatinib can better control recurrent hepatocellular carcinoma (HCC). It may help shrink tumors or slow growth for people whose cancer has come back but who have limited tumor burden.
Changsha, HunanAges 18–75 - NCT07428356Recruiting
Sound waves for liver tumors
This study tests a new, noninvasive treatment called histotripsy that uses sound waves to destroy small liver tumors. It is for people whose liver cancer hasn't spread much and who haven't had success with or can't have surgery or other standard treatments.
SingaporeAges 21–99 - NCT06362395RecruitingPhase 3
Very high single-dose radiation for liver tumors using MRI guidance
This trial tests a very high, single dose of radiation guided by MRI to destroy liver tumors that have spread from certain cancers. It may be a good option if you have 1 to 3 liver tumors that are away from sensitive organs and your liver is working well.
Toronto, OntarioAges 18 years+ - NCT06426992Recruiting
Microwave ablation for small liver tumors
This study tests a microwave ablation device to destroy small liver tumors (up to 4 cm) using heat, without major surgery. It is designed for patients with limited disease (1 or 2 tumors) and good liver function.
SeoulAges 20–85 - NCT03844399Recruiting
3D ultrasound imaging during liver or kidney procedures
This study uses a new 3D ultrasound scan while you get standard care for a liver or kidney biopsy or ablation. The goal is to see whether the imaging is clear and useful during these procedures.
London, OntarioAges 18 years+ - NCT02886104Recruiting
Surgery versus local ablation for certain liver metastases
This trial compares two ways to treat colorectal cancer that has spread to the liver: removing liver tumors with surgery versus destroying them in place with local ablation. It may help doctors learn which approach works best for people whose disease can be fully treated and who have enough healthy liver left.
Guangzhou, GuangdongAges 18–80 - NCT07303725Recruiting
Spectral CT scan during cancer tumor treatment
This study tests a special CT scan used during procedures to treat tumors, like blocking blood flow or burning the tumor. It may help doctors see tumors more clearly during the treatment.
Palo Alto, CaliforniaAges 18 years+ - NCT04798898Recruiting
RFA plus immune stimulation during liver surgery for colon cancer spread
This trial looks at whether using a heat-based treatment (RFA) to trigger the immune system before or during liver surgery can improve outcomes for people with colon cancer that has spread to the liver. It’s aimed at people who plan to have the liver tumors removed because they look treatable.
AarhusAges 18–99 - NCT03981497Recruiting
Microwave treatment for small, hard-to-remove liver and kidney tumors
This trial tests using a “microwave ablation” procedure to destroy small liver or kidney tumors when surgery isn’t an option or can’t remove everything. It may help patients avoid major surgery by targeting tumors directly with heat.
MilanAges 18 years+ - NCT07159048Recruiting
Heat therapy for liver tumors
This trial tests a heat-based treatment for liver cancer tumors that uses multiple methods to destroy cancer cells. It may help people with liver tumors that haven't spread and who are healthy enough for treatment.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07223307RecruitingPhase 2
MRI-guided radiation for liver cancers
This trial tests a precise MRI-guided radiation treatment for liver cancers, including liver cancer, bile duct cancer, or cancer that has spread to the liver. The goal is to target tumors more accurately while protecting healthy tissue.
Palo Alto, CaliforniaAges 18 years+ - NCT06307080Recruiting
Combined ablation and immunotherapy for pancreatic cancer with liver spread
This study tests a new treatment combining tumor destruction with heat/cold (ablation) and an immunotherapy drug (PD-1) for people whose pancreatic cancer has spread to the liver. The goal is to help the immune system fight the cancer better.
Shanghai, Shanghai MunicipalityAges 18–70
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Common questions
- Are there clinical trials for liver ablation?
- Yes. Clin2 currently lists 30 recruiting liver ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.