Clinical trials
Liver Diseases clinical trials
Below are recruiting liver diseases clinical trials, each written for real people, not researchers. We’re tracking 444 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06741904Enrolling by invitation
Predicting liver disease worsening without invasive tests
This study looks at new, non-invasive methods to predict when chronic liver disease might get worse. It could help you and your doctor catch problems early without needing a biopsy or other invasive procedures.
Guangzhou, GuangzhouAges 18–80 - NCT06656767Enrolling by invitation
Studying liver cell changes in chronic liver disease
This trial uses already collected liver tissue samples from adults to study how cells change over time in chronic liver disease. It could help researchers understand the disease better and find new ways to treat it.
CambridgeAges 18 years+ - NCT05744713Enrolling by invitation
Study of adults with long-term liver disease using health records
This observational study looks at adults with chronic liver disease (including cirrhosis) to better understand how people are managed and how they feel over time. Because it does not change your treatment, it may help researchers improve care and patient support.
Los Angeles, CaliforniaAges 18 years+ - NCT07670611RecruitingPhase 4
Vitamin D2 alone or with calcitriol for children with liver disease
This trial compares two types of vitamin D—one is plain vitamin D2, the other is vitamin D2 plus a more active form (calcitriol)—to see which works better for children with liver problems and low vitamin D levels.
BangkokAges Up to 18 years - NCT06825559RecruitingPhase 1
Saroglitazar safety in moderate liver impairment from cholestatic disease
This trial tests how the body processes saroglitazar in people with moderate liver impairment caused by cholestatic liver disease. The goal is to ensure the drug is safe and dosed correctly for this group.
Indianapolis, IndianaAges 18–80 - NCT03131427Recruiting
Registry for inherited liver and metabolism-related conditions
This is a study that collects health information and samples (if applicable) from people with certain genetic or metabolic liver diseases. It may help doctors better understand these conditions and improve future care.
Beijing, Beijing MunicipalityAges Any age - NCT03175471Recruiting
MRI study of blood-vessel and tissue signs in child liver disease
This trial uses MRI scans to look for “biomarkers,” which are measurable signs in the liver, to better understand autoimmune liver diseases in children and teens. It may help doctors track disease and improve care by finding imaging patterns linked to illness.
Cincinnati, OhioAges 6–23 - NCT03267069Recruiting
Study of alcohol use in alcoholic liver disease
This study looks at alcohol use behaviors in people who have alcoholic liver disease. It may help researchers better understand patterns of alcohol use and how to support safer health decisions.
New York, New YorkAges 18–80 - NCT04106518Recruiting
Genetics study of alcohol-related liver disease and cirrhosis
This study looks at genetic differences in people with alcohol-related liver illness, including a recent jaundice episode (alcoholic hepatitis). By following people over time, it may help doctors better predict illness and understand why some people develop worse liver problems.
AngersAges 18 years+ - NCT04320199Recruiting
Fermented beetle powder for alcohol-related liver problems
This trial tests whether a fermented powder made from a specific beetle can improve or protect the liver after alcohol-related liver injury. It’s looking for people with certain liver blood test levels, and it excludes several conditions and recent herbal or liver-affecting treatments.
Pusan, Ami-dongAges 19 years+ - NCT05478083RecruitingPhase 2
Leuprolide treatment for severe polycystic liver growth
This Phase 2 study tests whether a monthly hormone medicine (leuprolide, a GnRH agonist given as an injection) can slow down ongoing, fast-growing polycystic livers. It is aimed at pre-menopausal women with very large livers that are still getting bigger on past and current scans.
Nijmegen, GelderlandAges 18–45 - NCT05865691Recruiting
Study blood and organ changes in chronic liver disease
This study looks at how blood clotting, inflammation, and blood vessels change in people with chronic liver disease or cirrhosis. Your blood tests may help researchers understand what drives the disease and could guide future care.
ClichyAges 18 years+ - NCT06588699RecruitingPhase 2
Digoxin for NASH liver disease study
This trial tests if the heart medication digoxin can help people with NASH (fatty liver disease with inflammation), who have moderate liver scarring. You will receive digoxin or a placebo for 24 weeks and have a liver biopsy before and after treatment to see if the medication reduces liver damage.
New Haven, ConnecticutAges 18–75 - NCT07028580Recruiting
High-Protein Plant Diet for Liver Cirrhosis
This study tests whether a special diet high in plant-based protein (with some animal protein) can help people with severe liver cirrhosis who are waiting for a kidney transplant. The diet aims to improve nutrition and health without overloading the liver.
Athens, AtticaAges 18–80 - NCT03178630Recruiting
MRI scans to track outcomes in children with autoimmune liver disease
This study uses MRI scans to find “biomarkers,” or imaging clues, that may help predict how autoimmune liver conditions will progress in children and young adults. If you qualify, you may get MRI imaging to see whether it relates to future health outcomes.
Cincinnati, OhioAges 6–23 - NCT06888570Enrolling by invitation
Liver health study for children & young adults with Down syndrome
This study looks at how eating patterns and body composition relate to fatty liver in children and young adults with Trisomy 21 (Down syndrome) or other genetic intellectual disabilities. It may help understand who is at risk and how to prevent liver problems.
Madrid, MadridAges 5–22 - NCT07070362Recruiting
Digital early warning system for lung injury after liver surgery
This trial tests a digital early warning system to detect acute lung injury after liver surgery. It may help doctors catch breathing problems early so they can treat them faster.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07192159Recruiting
Ultrasound vs MRI for measuring liver fat in MASLD
This study compares ultrasound (DeepUSFF) and MRI (MRI-PDFF) for measuring liver fat in people with MASLD (a type of fatty liver disease not caused by alcohol). It aims to see if ultrasound can be used as a cheaper, more accessible alternative to MRI.
Boardman, OhioAges 18 years+ - NCT07009860RecruitingPhase 2
Testing pemvidutide for alcohol-related liver disease
This trial tests a study drug called pemvidutide to see if it can help people with liver damage caused by heavy alcohol use. You may be able to join if you have a history of heavy drinking and have some liver stiffness but not too severe.
Peoria, ArizonaAges 18–75 - NCT06434753RecruitingPhase 3
Zinc supplements for stable advanced liver disease
This trial tests whether taking zinc supplements can improve the outlook for people with a certain type of advanced liver disease that is still stable (no major complications). If you have compensated advanced chronic liver disease and meet the criteria, you might be able to join.
BarcelonaAges 18–80 - NCT06939569Recruiting
Studying fatty liver disease in people with inflammatory bowel disease
This study looks at how common non-alcoholic fatty liver disease is in people with inflammatory bowel disease (Crohn's or colitis). Researchers want to learn more about the link between the two conditions.
ShanghaiAges 18 years+ - NCT02422238Recruiting
Study of fatty liver in adults, using MRI and stored samples
This study follows people with nonalcoholic fatty liver disease to better understand the condition. It uses an MRI scan and collects body samples to help researchers study changes over time.
Maastricht, LimburgAges 18–65 - NCT06944353Enrolling by invitation
Fatty liver risk screening in the emergency department
This study looks at fatty liver findings on emergency department scans. If you have fatty liver and were sent home from the ED, the study may help connect you to follow-up care and avoid future liver problems.
Chicago, IllinoisAges 18 years+ - NCT03813862Recruiting
Study tracking medicines from clinic records
This is an observational study that collects information about what medicines patients receive. It uses data already recorded in participating clinics’ computer health records to better understand medication use over time.
Durham, North CarolinaAges birth+
Hear when a new Liver Diseases trial opens
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Common questions
- Are there clinical trials for liver diseases?
- Yes. Clin2 currently lists 444 recruiting liver diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.