Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03474822RecruitingPhase 1/Phase 2
Plasmodium immune treatment for breast and liver cancers
This early-phase study tests an immune-based treatment (using Plasmodium) for people with advanced breast cancer or advanced liver cancer. It aims to see whether the treatment is safe and whether it can help the body’s immune system fight the cancer.
Guangzhou, GuangdongAges 18–70 - NCT02060565Recruiting
Test noninvasive scans to diagnose chronic liver disease
This study looks at how well noninvasive tests (tests that don’t require surgery, like scans and blood-based measurements) can diagnose chronic liver disease in people with certain liver conditions. It may help doctors choose better, less invasive ways to identify the type and stage of liver problems.
PessacAges 18 years+ - NCT06075745RecruitingPhase 2
CMV Vaccine Study for Liver Transplant Candidates
This trial tests a vaccine to prevent cytomegalovirus (CMV) infection in people awaiting a first liver transplant. You may be eligible if you have never been infected with CMV and are scheduled to receive a liver transplant within the next 1 to 12 months.
Birmingham, AlabamaAges 18 years+ - NCT07656181Recruiting
Standardizing quality criteria for liver ultrasound with contrast
This trial gathers expert doctors to create standard quality rules for liver ultrasound exams that use contrast dye. If you're a very experienced ultrasound doctor, your opinion could help shape future care.
Bern, Canton of BernAges Any age - NCT06533592Recruiting
Bile duct connection technique in liver transplant
This study compares two ways of connecting the bile duct during a liver transplant to see which leads to a smoother recovery. It is for adults having a planned first transplant from a deceased donor.
Warsaw, Masovian VoivodeshipAges 18–75 - NCT06354179RecruitingPhase 4
Once-daily immunosuppression after liver transplant
This study tests whether taking immunosuppressive drugs (tacrolimus and mycophenolate mofetil) just once a day, instead of twice, works as well for people who recently had a liver transplant. The goal is to make the medication schedule easier and possibly safer.
BesançonAges 18 years+ - NCT07660679Recruiting
Carotid ultrasound before liver transplant surgery
This study looks at whether measuring the thickness of the carotid artery (the main artery in the neck) before a planned liver transplant can help doctors predict and manage blood flow changes during surgery. It may help patients get safer care during their transplant.
DiyarbakırAges 18 years+ - NCT06754514Recruiting
Organ retractor device study for weight loss surgery
This trial is testing a device that helps surgeons perform weight loss surgery through small incisions. It may be for you if you are scheduled for minimally invasive bariatric surgery.
Raleigh, North CarolinaAges 18 years+ - NCT06801665RecruitingPhase 2
Fecal transplant plus immunotherapy and chemotherapy for colon cancer with liver spread
This trial tests a combination of fecal microbiota transplant (FMT), an immunotherapy drug (QL1706), a targeted therapy (bevacizumab), and chemotherapy (XELOX) as a first treatment for advanced colon cancer that has spread to the liver. The goal is to see if this mix can help shrink tumors and improve outcomes.
ChangzhouAges 18–75 - NCT03789383Recruiting
Living donor liver transplant and biliary complication outcomes study
This study looks at what factors lead to “biliary complications” (problems involving the bile ducts that help move bile from the liver) after an adult living-donor liver transplant. It’s aimed at people who had this specific type of transplant at the study hospital in Egypt.
AsyutAges 18–65 - NCT06690528RecruitingPhase 2
Surgery vs. palliative care for pancreatic cancer with limited liver spread
This trial compares surgery to remove the primary tumor and up to 3 liver spots against standard palliative care for people with pancreatic cancer that has spread only to the liver (up to 3 spots). It is for those whose cancer has not grown after initial chemotherapy and who are healthy enough for surgery.
Padova, ItalyAges 18–75 - NCT07534241Recruiting
Reishi Mushroom for Fatty Liver Disease
This study tests whether reishi mushroom (a type of fungus) can improve liver health in people with metabolic dysfunction-associated fatty liver disease—a condition where fat builds up in the liver. Researchers want to see if this natural supplement can reduce liver inflammation and improve blood sugar and cholesterol levels.
LahoreAges 35–65 - NCT06254248RecruitingPhase 2
Safety of two cancer drugs after liver transplant
This trial tests a combination of two drugs (atezolizumab and bevacizumab) for people whose liver cancer has returned after a liver transplant and cannot be treated with surgery or other local procedures. The goal is to see if this treatment is safe for liver transplant recipients.
ClichyAges 18–90 - NCT07050550Recruiting
PET imaging test for people with liver injury
This study tests a new PET imaging agent called ¹⁸F-DFA to see if it can measure liver damage and liver failure. It may help doctors better understand your liver condition using a specialized scan.
Hangzhou, ZhejiangAges 18–80 - NCT06741904Enrolling by invitation
Predicting liver disease worsening without invasive tests
This study looks at new, non-invasive methods to predict when chronic liver disease might get worse. It could help you and your doctor catch problems early without needing a biopsy or other invasive procedures.
Guangzhou, GuangzhouAges 18–80 - NCT05794971RecruitingPhase 3
Regorafenib with irinotecan beads for colorectal liver spread
This Phase 3 trial tests whether adding a pill called regorafenib to irinotecan “drug-eluting” beads placed in the liver can shrink colorectal cancer that has spread mainly to the liver after standard chemotherapy stops working. If you qualify, it may offer a new combination approach for controlling liver tumors.
Guangdong, GuangzhouAges 18–70 - NCT07090083Recruiting
Liver health and food support for children
This study tests whether providing fruit and vegetable vouchers to families with children who have fatty liver disease can improve liver health. Diet and lifestyle are key to managing this condition.
San Francisco, CaliforniaAges 6–17 - NCT05265169Recruiting
Tested microwave ablation to treat liver metastases from colon cancer
This study tests whether a specific heating treatment (microwave ablation) can completely destroy small colon cancer spots in the liver. It may help patients who have limited liver tumors and need a precise, minimally invasive option.
Miami, FloridaAges 18 years+ - NCT07530913Enrolling by invitation
Digital Rehabilitation Platform for Liver Transplant Patients
This study tests a smartphone or tablet-based exercise program designed to help people recovering from living donor liver transplant surgery. The goal is to see if using guided exercises on a digital device at home improves recovery and quality of life after transplant.
SeoulAges 20–65 - NCT05150145Recruiting
Radiation versus observation for liver spread of small cell lung cancer
This trial compares giving liver-directed radiation to watching closely without radiation. It is for people with small cell lung cancer that has spread to the liver, to see whether radiation helps control the disease.
Guiyang, GuizhouAges 18–70 - NCT06362395RecruitingPhase 3
Very high single-dose radiation for liver tumors using MRI guidance
This trial tests a very high, single dose of radiation guided by MRI to destroy liver tumors that have spread from certain cancers. It may be a good option if you have 1 to 3 liver tumors that are away from sensitive organs and your liver is working well.
Toronto, OntarioAges 18 years+ - NCT07117435RecruitingPhase 1
Targeted chemo into liver for colorectal cancer spread
This trial is testing a new way to give the chemotherapy drug paclitaxel directly into the liver (through a tiny tube) along with standard systemic treatment for people whose colorectal cancer has spread only to the liver and cannot be surgically removed. The goal is to see if this targeted approach works better than standard treatment alone.
Lishui, ZhejiangAges 18–75 - NCT07109440Recruiting
FAPI PET/CT scan for colorectal cancer liver spread
This study uses a special type of PET/CT scan (FAPI) to get a better look at the environment around colorectal cancer that has spread to the liver. It may help doctors learn more about the tumor and plan treatment.
BrusselsAges 18 years+ - NCT05829291Recruiting
Alpha Radiation Seeds for Liver Cancer Spread Treatment
This trial tests a new treatment called DaRT (alpha radiation seeds) implanted directly into liver tumors that have spread from colorectal cancer. The seeds deliver targeted radiation to shrink tumors while reducing damage to healthy liver tissue, as part of a two-stage surgical plan.
Montreal, QuebecAges 18 years+
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,253 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.