Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,219 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04588077RecruitingPhase 4
Two-dose vs three-dose hepatitis B vaccine for cirrhosis
This study compares giving the hepatitis B vaccine in 2 doses versus 3 doses for people with cirrhosis who do not yet have protection against hepatitis B. It may help your care team choose the schedule most likely to build lasting immunity.
Baltimore, MarylandAges 18 years+ - NCT07634562RecruitingPhase 1/Phase 2
Reducing immune-suppressing drugs after liver transplant
This study tests a new way to lower the amount of immune-suppressing medicine needed after a liver transplant. It uses special treatments before or during the transplant to help your body accept the new liver with fewer drugs, which may reduce side effects.
Stanford, CaliforniaAges 18–55 - NCT07632677Recruiting
Testing a liver inflammation score in diabetes and fatty liver
This study tests whether a new scoring method can help doctors identify liver inflammation in patients who have both type 2 diabetes and a fatty liver. The goal is to find an easier, safer way to assess liver health without invasive procedures.
Bengbu, AnhuiAges 18 years+ - NCT06519266RecruitingPhase 3
Liver treatment with immunotherapy for uveal melanoma that spread to the liver
This trial tests whether adding a liver-directed therapy (PHP) to a combination of two immunotherapy drugs (ipilimumab and nivolumab) works better than the immunotherapy drugs alone for people whose uveal melanoma has spread to the liver.
GothenburgAges 18 years+ - NCT05967143Recruiting
Registry study for first-time SIR-Spheres in liver tumors
This is an observational (real-world) study that follows people with certain unresectable liver tumors who are getting SIR-Spheres for the first time. It helps doctors understand how this treatment is used in routine care and what outcomes patients experience.
Clichy, CedexAges 18 years+ - NCT06704321Recruiting
Effects of TOTUM-448 on liver fat and heart health
This trial tests a supplement called TOTUM-448 to see if it can reduce liver fat and improve heart health in people with a fatty liver condition (MASLD). If you have excess liver fat and are overweight, this study could help find new ways to manage your condition.
Québec, QuebecAges 18–75 - NCT04310787Recruiting
Tracking outcomes in adults with hepatitis B liver failure
This study looks at long-term survival in people ages 18–65 who are hospitalized with hepatitis B–related acute-on-chronic liver failure. It may help doctors better predict prognosis and improve care for people with this serious condition.
Guangzhou, GuangdongAges 18–65 - NCT04597164Recruiting
Test a hepatitis B–targeted treatment for serious liver failure
This trial studies a combination approach called DPMAS and low-volume plasma exchange for people with hepatitis B–related acute-on-chronic liver failure. If you qualify, the goal is to improve your liver function and reduce serious complications from liver failure.
Guangzhou, GuangdongAges 18–65 - NCT07610837RecruitingPhase 2
Testing AZD2389 for fatty liver disease with scarring
This study tests whether a new drug called AZD2389 is safe and well-tolerated in adults with steatotic liver disease (fatty liver) that has progressed to advanced scarring. The trial aims to see if this drug might help slow or improve liver damage in people with this condition.
Chandler, ArizonaAges 18 years+ - NCT07603817Recruiting
Thyroid Disease and Fatty Liver Disease Study
This study looks at the connection between thyroid problems (especially when the thyroid doesn't make enough hormone) and a common liver condition where fat builds up in the liver. Researchers want to understand how these two conditions relate to each other in people without diabetes.
Sohag, Sohag GovernorateAges 18 years+ - NCT04502719Recruiting
Testing nutrition screening in people with liver cirrhosis
This study compares different ways of checking nutrition problems in people with liver cirrhosis. It may help doctors choose the best screening tool to spot risk earlier and guide care.
Barcelona, CataloniaAges 18–100 - NCT04971577RecruitingPhase 2/Phase 3
Simvastatin for alcohol-related liver scarring in stable adults
This trial studies whether simvastatin (a cholesterol medicine) can improve or slow scarring of the liver caused by long-term alcohol use. Participants must have confirmed liver fibrosis on biopsy and be in a stable (compensated) phase of liver disease.
BarcelonaAges 18 years+ - NCT07600788RecruitingPhase 1
Liver Function and Safety Study of AHB-137 Injection
This study tests how a new investigational drug called AHB-137 moves through your body and affects safety in people with mild-to-moderate liver problems compared to people with normal liver function. The goal is to understand if the drug works safely in people whose livers don't work as well as they should.
Chongqing, Chongqing MunicipalityAges 18–65 - NCT06716541Recruiting
Biodegradable stent for bile duct narrowing after liver transplant
This study is testing a special temporary stent that breaks down over time to help open a narrowed bile duct after a liver transplant. It may help avoid long-term plastic stents or additional surgery.
PragueAges 18 years+ - NCT07599241Recruiting
Exercise Program for Older Women With Thyroid, Eye, and Liver Conditions
This study tests whether a physical activity program can help older women manage three common conditions together: an underactive thyroid, high eye pressure (glaucoma), and fatty liver disease. Researchers want to see if exercise improves symptoms and overall health when addressing multiple conditions at once.
Dokki, Giza GovernorateAges 65–75 - NCT04798898Recruiting
RFA plus immune stimulation during liver surgery for colon cancer spread
This trial looks at whether using a heat-based treatment (RFA) to trigger the immune system before or during liver surgery can improve outcomes for people with colon cancer that has spread to the liver. It’s aimed at people who plan to have the liver tumors removed because they look treatable.
AarhusAges 18–99 - NCT06718842Recruiting
Walking program for children with PKU and fatty liver
This study tests whether a walking program can help children with PKU who also have fatty liver and obesity. It aims to see if regular walking improves liver health and overall fitness.
Dokki, Giza GovernorateAges 9–12 - NCT06717542Recruiting
Liver tissue analysis to predict transplant success
This study looks at liver tissue before transplantation to find ways to predict how well the transplant will work. It involves a special treatment called HOPE to help preserve the liver.
BolognaAges 18 years+ - NCT06717828Recruiting
Tai Chi for fatty liver in older adults
This trial tests whether Tai Chi, a gentle exercise, can improve fatty liver disease in middle-aged and older adults who are overweight. If you are between 40 and 75 and have metabolic fatty liver, you might be able to join.
Fuzhou, FujianAges 40–75 - NCT02185443RecruitingPhase 2
SBRT radiation for liver metastases that can’t be surgically removed
This trial studies stereotactic body radiation therapy (high-precision radiation given in a few sessions) for liver metastases when surgery isn’t possible. It may help shrink or control tumors in the liver and delay progression in people whose cancer has not spread outside the liver (or only to areas treated with a curative plan).
São Paulo, São PauloAges 18 years+ - NCT07574398Recruiting
Growth and Development Study After Infant Liver Transplant
This study tracks how babies grow and develop after receiving a liver transplant. Researchers want to understand how transplantation affects children's physical growth and overall development in early infancy.
Shanghai, Shanghai MunicipalityAges Up to 1 year - NCT06725121RecruitingPhase 1/Phase 2
Radiation and immunotherapy for advanced liver cancer before transplant
This trial tests combining radiation therapy with immunotherapy (AtezoBev) before a liver transplant for advanced liver cancer. The goal is to see if this approach can shrink tumors and make transplant possible for more people.
London, OntarioAges 18–70 - NCT06735118Recruiting
Can AI help see chemo-related fatty liver?
This study uses a special MRI technique and artificial intelligence to see how chemotherapy may cause a fatty liver. It may help find liver changes early in people who have had chemo.
Kunming, YunnanAges 18–80 - NCT06734013Recruiting
Genetic testing to help diagnose liver transplant rejection
This study looks at whether genetic testing of a tissue sample (biopsy) can help doctors more accurately diagnose rejection after a liver transplant. It is for people who have already been diagnosed with rejection and have a stored tissue sample available.
BolognaAges 18 years+
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,219 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.