Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05089604RecruitingPhase 4
Compare two tacrolimus forms to reduce tremors after liver transplant
This study compares immediate-release versus extended-release tacrolimus (an anti-rejection medicine) to see if one form causes fewer tremors after a first liver transplant. It may help you and your care team choose the best form if tremors are a problem while your body adjusts after transplant.
Vancouver, British ColumbiaAges 18 years+ - NCT05128890Recruiting
People who had prior pancreatic or liver surgery
This study looks back at people who previously had surgery to remove part of the pancreas or liver at a specific hospital. It aims to compare different resection (removal) techniques and how patients did afterward.
Dallas, TexasAges 18 years+ - NCT05169177Recruiting
Tracking liver tumor medicine on CT during radiation
This study checks whether a special “contrast” medicine used in liver cancer can be clearly seen on CT images while you receive radiation. The goal is to better track where the medicine is during treatment, which may improve how radiation is guided.
Waratah, New South WalesAges 18 years+ - NCT05170971Recruiting
Fecal transplant trial for worsening liver failure
This trial studies fecal microbiota transplantation (a transfer of healthy gut bacteria from a donor) to help people with worsening liver failure. It may help by changing gut bacteria, which can affect complications like confusion, fluid buildup, infections, and kidney problems.
Ningbo, ZhejiangAges 18–65 - NCT05195450Recruiting
Tenofovir to stop liver disease in mild hepatitis B
This trial tests tenofovir alafenamide (a hepatitis B antiviral medicine) to see if it can prevent liver disease from getting worse in people with chronic hepatitis B who currently have stable (normal) liver blood tests and low virus levels. It may help lower the chance of developing serious liver complications over time.
New Delhi, National Capital Territory of DelhiAges 18–70 - NCT05195710RecruitingPhase 1
Pre-surgery Y-90 treatment to grow future liver volume
This trial tests a radiation treatment called Y-90 given before liver surgery for colorectal cancer that has spread to the liver. The goal is to help the liver grow enough for safer, curative surgery, either right away or as part of a two-step operation.
Houston, TexasAges 18 years+ - NCT05240950RecruitingPhase 1
CAR-T cell therapy for colorectal cancer in the liver
This Phase 1 study tests an anti-CEA CAR-T cell treatment for people whose colorectal cancer spread to the liver but has been surgically removed with no visible remaining tumor. It aims to see if the treatment can better prevent the cancer from coming back, especially when early warning tests suggest leftover cancer cells.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05242315RecruitingPhase 4
Long-acting tacrolimus after liver transplant
This trial studies whether taking an extended-release form of tacrolimus (a medicine to prevent transplant rejection) after a liver transplant works well for people who are followed at the University of Alberta. It may help simplify dosing and monitor safety and effectiveness after transplant.
Edmonton, AlbertaAges 18 years+ - NCT05264051Recruiting
MRI scan to predict outcomes in liver disease
This study looks at MRI images taken as part of routine care to see if they can help predict future health problems in people with liver disease. If you already have an MRI scheduled for clinical reasons, this may help doctors better estimate risk over time.
Chicago, IllinoisAges 18 years+ - NCT05294471Recruiting
Automated MRI to measure liver fat and iron
This study uses an automated MRI scan to measure things in the liver, such as liver fat and iron levels. It may help researchers better understand liver changes and improve how these measurements are done.
Madison, WisconsinAges 7 years+ - NCT05304234RecruitingPhase 2
Testing ways to detect liver cancer risk in Native patients
This Phase 2 study focuses on people at higher risk for liver cancer due to liver scarring or chronic hepatitis B. It may help improve screening and outcomes for American Indian and Alaska Native people who could benefit from closer monitoring.
Tahlequah, OklahomaAges 18–75 - NCT05309863Recruiting
Compare home versus clinic weight programs for fatty liver
This study compares two weight-loss programs for children with fatty liver disease related to weight, to see which helps the liver and health better. You may be eligible if your child is already enrolled in a lifestyle program for childhood obesity and meets key safety checks.
Ghent, East-FlandersAges 8–18 - NCT05325424Recruiting
Laparoscopic spleen surgery for people with cirrhosis
This study looks at whether removing the spleen using keyhole surgery can improve “liver reserve function” in people with cirrhosis. It may be considered for patients who have an enlarged spleen and very low platelets, but it also has several safety exclusions.
Yangzhou, JiangsuAges 18 years+ - NCT05325437Recruiting
Laparoscopic spleen surgery to protect liver function in cirrhosis
This trial looks at whether a minimally invasive spleen surgery (with a specific vein-disconnection procedure) can better protect liver function in people with cirrhosis who have had variceal bleeding. It may help reduce stress on the liver after treatment, but you must meet several safety criteria.
Yangzhou, JiangsuAges 18 years+ - NCT05326399Recruiting
Kidney biopsies after liver transplant for new kidney problems
This trial studies kidney biopsies in people who had a liver transplant and then developed new signs of kidney damage. The goal is to better understand what’s causing the problem and how to guide next steps.
ShanghaiAges 18–75 - NCT05332613Recruiting
Diet and meal timing study for fatty liver
This study looks at whether changing when and how people eat can improve fatty liver disease caused by metabolic problems. It uses MRI to measure liver fat and compares outcomes while participants follow a structured eating schedule.
New York, New YorkAges 18–65 - NCT05335603Recruiting
Study of adults with liver conditions linked to fatty liver
This study looks at adults with different long-term liver conditions that are associated with fatty liver. It helps researchers better understand these diseases and factors linked to them.
HvidovreAges 18 years+ - NCT05366829RecruitingPhase 2
Tislelizumab after liver tumor radiation to reduce cancer return
This Phase 2 trial tests tislelizumab (an immunotherapy medicine) given after liver-directed radiation to help prevent hepatocellular carcinoma (liver cancer) from coming back or spreading. It may help by boosting the immune system to better control remaining cancer.
New Brunswick, New JerseyAges 18 years+ - NCT05439226Recruiting
Diet plan targeting liver fat for type 2 diabetes
This study tests whether a Chinese medical nutrition therapy diet can reduce liver fat and help manage type 2 diabetes in people who also have fatty liver. You may be asked to follow a specific eating plan and keep your diabetes care stable during the study.
Yichang, HubeiAges 18–75 - NCT05478083RecruitingPhase 2
Leuprolide treatment for severe polycystic liver growth
This Phase 2 study tests whether a monthly hormone medicine (leuprolide, a GnRH agonist given as an injection) can slow down ongoing, fast-growing polycystic livers. It is aimed at pre-menopausal women with very large livers that are still getting bigger on past and current scans.
Nijmegen, GelderlandAges 18–45 - NCT05492136Recruiting
Radiofrequency during liver surgery to reduce cancer coming back
This study looks at whether using radiofrequency (a heat-based treatment used during surgery) during liver surgery can lower the chances that cancer returns locally. It includes people with colorectal cancer that has spread to the liver and people with liver cancer (HCC).
BarcelonaAges 18 years+ - NCT05502198Recruiting
How muscle loss matters in advanced liver disease
This study looks at how loss of muscle strength or mass (sarcopenia) relates to advanced liver disease. It may help doctors understand which patients are at higher risk and could guide future care choices.
EksjöAges 18 years+ - NCT05528471Recruiting
Test whether fructose affects fatty liver in teens
This study looks at how fructose (a type of sugar) may affect fatty liver disease (NAFLD) in teens with obesity. The goal is to learn whether fructose changes liver health, using MRI/MRS scans to measure the liver.
Edmonton, AlbertaAges 12–18 - NCT05554224Recruiting
Personalized treatment based on obesity-related fatty liver tests
This study uses multiple types of health data (“multi-omics”) to help choose a personalized treatment plan for people with obesity-related fatty liver disease. It may help match treatment to your biology to improve outcomes.
Reus, TarragonaAges 18 years+
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,253 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.