Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06356584RecruitingPhase 2
A drug combination with or without radiation for advanced colorectal cancer
This trial tests a new drug combo (fruquintinib and sintilimab) with or without radiation for people with colorectal cancer that has spread to the liver and has not responded to earlier treatments.
Jinan, ShandongAges 18–75 - NCT06359444Recruiting
Exercise therapy for fatty liver disease
This study tests whether a high-intensity exercise program can improve liver function and insulin sensitivity in people with MASLD (a type of fatty liver disease). It may help you if you are looking for a non-drug way to manage your condition.
GhentAges 18–75 - NCT06368882RecruitingPhase 4
Peg-interferon for hepatitis B with fatty liver
This trial tests a medicine called peg-interferon for people who have both chronic hepatitis B and fatty liver. It aims to see if the treatment is safe and effective in helping your body fight the hepatitis B virus.
NingboAges 18–60 - NCT06400771RecruitingPhase 1
Safety of DNP007 in Healthy Volunteers
This study tests the safety of a new drug called DNP007 in healthy volunteers. It is a Phase 1 trial, meaning it's one of the first steps in humans to see if the drug is safe and how the body handles it.
SeoulAges 19–55 - NCT06434753RecruitingPhase 3
Zinc supplements for stable advanced liver disease
This trial tests whether taking zinc supplements can improve the outlook for people with a certain type of advanced liver disease that is still stable (no major complications). If you have compensated advanced chronic liver disease and meet the criteria, you might be able to join.
BarcelonaAges 18–80 - NCT06446609Recruiting
Itching in drug-induced liver injury study
This study looks at itching caused by drug-induced liver injury. Researchers want to understand who gets itchy and how bad it is, which could help improve care for people with this condition.
NottinghamAges 18 years+ - NCT06449339RecruitingPhase 4
Beta-blocker study for early-stage liver scarring
This study tests a medicine called carvedilol (a non-selective beta-blocker) to see if it can prevent complications in people with advanced chronic liver disease who are at high risk but haven't had serious problems like bleeding yet.
Hong KongAges 18 years+ - NCT06449937Recruiting
Local liver treatment for colorectal cancer that has spread
This trial tests whether treating liver tumors with surgery or ablation can help people whose colorectal cancer has spread to the liver and other organs. It may be an option if you've had only 1 or 2 types of chemotherapy and your non-liver metastases are stable.
Chuzhou, AnhuiAges 18–80 - NCT07692438Recruiting
Can Taiwan green propolis help with fatty liver and body fat?
This trial tests whether a natural supplement called Taiwan green propolis can improve blood fats and reduce body fat in people with fatty liver disease (MASLD). If you have fatty liver plus at least one related health issue like high cholesterol, diabetes, or high blood pressure, you may be eligible.
DalinAges 18–80 - NCT06496191Recruiting
Fecal transplant for alcohol use in cirrhotics
This trial tests whether a fecal microbiota transplant (FMT) can help people with alcohol-related cirrhosis who are still drinking. It aims to see if FMT can reduce alcohol cravings and improve liver health.
New Delhi, National Capital Territory of DelhiAges 18–70 - NCT06506318Recruiting
Predicting drug-resistant liver abscess with deep learning
This trial uses a computer model based on deep learning to predict whether a bacterial liver abscess will be resistant to multiple antibiotics. It looks at your CT scan images to help doctors choose the right treatment sooner.
Shenyang, LiaoningAges 18 years+ - NCT06508190Recruiting
Walking exercise for sleep apnea and fatty liver
This trial tests whether a simple walking program can help people who have both obstructive sleep apnea and non-alcoholic fatty liver disease. If you have these conditions and a BMI under 35, you may be able to join a free exercise program to see if it improves your health.
GizaAges 40–65 - NCT06509230Recruiting
Predicting serious liver scarring in hepatitis B patients
This study looks at better ways to predict significant liver fibrosis (scarring) in people with chronic hepatitis B or non-alcoholic fatty liver disease. It aims to help avoid invasive tests like liver biopsy.
Hangzhou, ZhejiangAges 18–60 - NCT06512701Recruiting
Fat-soluble vitamins and fatty liver disease study
This study looks at how fat-soluble vitamins (like vitamins A, D, E, and K) are related to non-alcoholic fatty liver disease (NAFLD). It may help understand if vitamin levels affect your liver health.
Hangzhou, ZhejiangAges 18 years+ - NCT06519266RecruitingPhase 3
Liver treatment with immunotherapy for uveal melanoma that spread to the liver
This trial tests whether adding a liver-directed therapy (PHP) to a combination of two immunotherapy drugs (ipilimumab and nivolumab) works better than the immunotherapy drugs alone for people whose uveal melanoma has spread to the liver.
GothenburgAges 18 years+ - NCT06535945RecruitingPhase 4
Albumin to protect kidney function after liver transplant
This trial tests whether giving albumin (a protein in your blood) after a liver transplant can help prevent or reduce kidney damage. It is for adults receiving their first liver-only transplant from a deceased donor.
Chambray-lès-ToursAges 18 years+ - NCT06555003RecruitingPhase 3
DEBIRI plus chemo vs. chemo alone for liver metastases
This trial tests if a treatment called DEBIRI (tiny beads delivering chemo directly to the liver) plus standard chemotherapy works better than chemotherapy alone for colorectal cancer that has spread to the liver and can't be fully removed by surgery.
Tehran, Tehran ProvinceAges 18 years+ - NCT06566105Recruiting
Fatty liver study for blood donors with weight concerns
This study collects blood samples from donors with excess weight or related health issues to better understand fatty liver disease. If you are a blood donor between 40 and 65, and have overweight, high blood sugar, abnormal cholesterol, or high blood pressure, you may be able to help.
Milan, MilanoAges 40–60 - NCT06567353Recruiting
Heat-based immunotherapy for breast cancer liver metastases
This trial tests a new treatment that uses heat to target liver tumors and boost the immune system. It is for women with breast cancer that has spread to the liver who cannot have or do not want surgery.
ShanghaiAges 18–75 - NCT06576934Recruiting
Early TIPS for liver cirrhosis with ascites
This study tests whether placing a small tube (called a TIPS) early in the liver can help people with cirrhosis who have their first episode of moderate to severe belly fluid buildup. The goal is to see if this early procedure improves outcomes compared to standard care.
Freiburg im BreisgauAges 18–80 - NCT06588699RecruitingPhase 2
Digoxin for NASH liver disease study
This trial tests if the heart medication digoxin can help people with NASH (fatty liver disease with inflammation), who have moderate liver scarring. You will receive digoxin or a placebo for 24 weeks and have a liver biopsy before and after treatment to see if the medication reduces liver damage.
New Haven, ConnecticutAges 18–75 - NCT06596109Recruiting
Honey and lifestyle for fatty liver
This study tests if adding honey to your daily routine helps improve fatty liver in people with obesity. It may offer a simple way to support liver health alongside lifestyle changes.
Dokki, Giza GovernorateAges 30–50 - NCT06599918RecruitingPhase 2
Nicotinamide for liver scarring in fatty liver disease
This study tests whether nicotinamide (a form of vitamin B3) can help reduce liver scarring in people with nonalcoholic fatty liver disease. You may qualify if you have moderate to severe liver scarring and are between 18 and 85 years old.
BarcelonaAges 18–85 - NCT06836609RecruitingPhase 1/Phase 2
Study of a new drug for fatty liver disease (MASLD/MASH)
This study tests a new drug called ALN-CIDEB for people with fatty liver disease (MASLD or MASH). The goal is to see if it can reduce liver fat and improve liver health. You may qualify if you have a higher BMI and evidence of liver fat on imaging tests.
Chandler, ArizonaAges 18–65
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,253 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.