Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,219 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06559878Enrolling by invitation
Liver Mitochondria Study in Fatty Liver Disease
This study looks at how the liver's mitochondria (the energy powerhouses of cells) work in people with fatty liver disease. Participants will have an MRI scan and receive a small amount of fat solution through an IV to see how the liver processes fat.
Helsinki, UusimaaAges 18–75 - NCT06566105Recruiting
Fatty liver study for blood donors with weight concerns
This study collects blood samples from donors with excess weight or related health issues to better understand fatty liver disease. If you are a blood donor between 40 and 65, and have overweight, high blood sugar, abnormal cholesterol, or high blood pressure, you may be able to help.
Milan, MilanoAges 40–60 - NCT06535945RecruitingPhase 4
Albumin to protect kidney function after liver transplant
This trial tests whether giving albumin (a protein in your blood) after a liver transplant can help prevent or reduce kidney damage. It is for adults receiving their first liver-only transplant from a deceased donor.
Chambray-lès-ToursAges 18 years+ - NCT06519448Enrolling by invitation
Testing a pill for non-alcoholic fatty liver disease
This trial tests a diabetes drug called empagliflozin to see if it can reduce fat and inflammation in the liver in people with a specific type of fatty liver disease called NASH. It may help if you have NASH and either have type 2 diabetes or don't have it.
PragueAges 18–75 - NCT06519331Recruiting
Testing a new method for liver stiffness measurement
This study tests a new, non-invasive way to measure liver stiffness using a device called FibroScan. It aims to make liver checkups easier and more comfortable for people with liver disease.
OrsayAges 18 years+ - NCT06506513Recruiting
Can exercise help fatty liver disease?
This study tests whether a program of physical activity can reduce fat in the muscles and liver of people with MASLD, a type of fatty liver disease linked to metabolism. It looks at how exercise might help improve liver health.
BrusselsAges 18–70 - NCT03627013RecruitingPhase 3
Compare two transplant fluid solutions for kidney, liver, pancreas
This Phase 3 study compares two types of transplant fluid (Custodiol-N vs Custodiol) to protect organs while they are stored before surgery. It may help by reducing damage to the kidney, liver, or pancreas during transplant preparation.
GrazAges 18 years+ - NCT06446609Recruiting
Itching in drug-induced liver injury study
This study looks at itching caused by drug-induced liver injury. Researchers want to understand who gets itchy and how bad it is, which could help improve care for people with this condition.
NottinghamAges 18 years+ - NCT06432582Recruiting
Liver disease blood marker study for people with stiff livers
This study looks at whether certain micro-RNA levels in your blood can help predict how your chronic liver disease is progressing. It is for people who already have some liver stiffness (measured by a special ultrasound) and are being treated at the University Hospital St. Pölten.
Sankt Pölten, Lower AustriaAges 18 years+ - NCT04801290Recruiting
TIPS procedure for people with worsening liver cirrhosis
This trial studies the TIPS procedure in people with decompensated (worsening) liver cirrhosis to see how it helps. You may be considered if you need a TIPS procedure and can receive care at the study hospital.
Hanover, Lower SaxonyAges 18–99 - NCT06152250Recruiting
Fatty liver inflammation study with liver biopsy
This study looks at how the liver's immune environment changes in people with non-alcoholic fatty liver disease (NAFLD) that has progressed to significant scarring. Researchers will use a liver biopsy to understand the inflammation better, which may lead to new treatments.
Lyon, Auvergne-Rhône-AlpesAges 18 years+ - NCT06362395RecruitingPhase 3
Very high single-dose radiation for liver tumors using MRI guidance
This trial tests a very high, single dose of radiation guided by MRI to destroy liver tumors that have spread from certain cancers. It may be a good option if you have 1 to 3 liver tumors that are away from sensitive organs and your liver is working well.
Toronto, OntarioAges 18 years+ - NCT05060289Recruiting
Predicting drug-related liver injury using blood tests and expert review
This trial builds a prediction model to identify drug-related liver injury (DILI) by looking at your blood test patterns, timing, and expert diagnosis. It may help improve how doctors recognize this condition earlier and more accurately.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06349642Recruiting
Testing a live tumor test for immune therapy response
This trial uses a special test on live tumor samples to see if it can predict how well immune checkpoint inhibitors (a type of immunotherapy) will work for different cancers. It may help doctors choose the best treatment for you.
Phoenix, ArizonaAges 18 years+ - NCT06355310RecruitingPhase 2
Studying an SGLT2 inhibitor for fatty liver in teens
This study tests a medication called empagliflozin (a type of SGLT2 inhibitor) to see if it can help treat fatty liver disease in teenagers and young adults. It may improve liver health and help with weight management.
Chicago, IllinoisAges 16–20 - NCT06342557Recruiting
App-Based Health Diary for Young Liver Transplant Patients
This study uses an app (ePRO Diary) to track your health after a liver transplant or while waiting for one. It’s designed for young people between 14 and 20 years old who are moving from pediatric to adult care.
Bergamo, MILANOAges 14–20 - NCT06354179RecruitingPhase 4
Once-daily immunosuppression after liver transplant
This study tests whether taking immunosuppressive drugs (tacrolimus and mycophenolate mofetil) just once a day, instead of twice, works as well for people who recently had a liver transplant. The goal is to make the medication schedule easier and possibly safer.
BesançonAges 18 years+ - NCT06344442RecruitingPhase 3
Low-dose vasopressin for kidney protection after liver transplant
This trial tests whether giving a low dose of a hormone called vasopressin after a liver transplant can help prevent kidney injury. It's for adults scheduled for a planned liver transplant.
ParisAges 18 years+ - NCT06356584RecruitingPhase 2
A drug combination with or without radiation for advanced colorectal cancer
This trial tests a new drug combo (fruquintinib and sintilimab) with or without radiation for people with colorectal cancer that has spread to the liver and has not responded to earlier treatments.
Jinan, ShandongAges 18–75 - NCT06305624Recruiting
Smartphone app to help people with alcohol-related liver disease stop drinking
This trial tests whether a smartphone program can help people with alcohol-related liver disease reduce or stop drinking. If you have liver disease related to alcohol and have used alcohol in the past 6 months, this app-based support may be for you.
Lansing, MichiganAges 18 years+ - NCT06300463RecruitingPhase 2
Immunotherapy combinations for colorectal cancer with liver tumors
This trial tests combinations of immunotherapy drugs for people with colorectal cancer that has spread to the liver and is scheduled for surgery. The goal is to see if these treatments are safe and effective before and after the operation.
New York, New YorkAges 18 years+ - NCT06280950RecruitingPhase 2
Lowering immunosuppression after liver transplant with everolimus
This study tests whether adding the drug everolimus can safely reduce the amount of tacrolimus (an anti-rejection medicine) needed after a first liver transplant. This may help protect your kidneys while still preventing organ rejection.
Phoenix, ArizonaAges 18 years+ - NCT06291571Enrolling by invitation
Gut bacteria and body response in liver disease
This study looks at the bacteria in your gut (microbiome) and how your body responds to liver disease. Researchers want to learn if these factors can help improve care for people with liver problems.
AberdeenAges 18–70 - NCT06287723Recruiting
Blood test for cancer DNA after liver surgery in colorectal cancer
This study uses a simple blood test (liquid biopsy) to look for tiny bits of cancer DNA after surgery for colorectal cancer that spread to the liver. It aims to see if this test can find cancer earlier than standard scans, which may help guide future treatment decisions.
MontpellierAges 18 years+
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,219 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.