Clinical trials
Lower Back Pain clinical trials
Below are recruiting lower back pain clinical trials, each written for real people, not researchers. We’re tracking 126 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06540456Enrolling by invitation
Capsaicin patch for nerve-related lower back pain
This study tests a medicated patch called Qutenza (capsaicin) to treat chronic lower back pain that involves nerve damage. The patch is placed on the skin to help reduce pain signals.
Summerville, South CarolinaAges 18 years+ - NCT04074798Recruiting
Breathing over fast and slow movements for back pain
This study tests how breathing changes (hyperventilation) might affect people with long-lasting low back pain. It may help researchers understand triggers or symptoms, and compare them to people who do not have back pain.
HasseltAges 20–60 - NCT05100381Recruiting
Dry needling for long-lasting lower back muscle pain
This study tests whether dry needling (thin needles placed into specific muscles) can reduce moderate, long-lasting lower back pain. It focuses on people who have pain from trigger points in a specific back muscle, rather than pain caused by other medical problems.
Tehran, Tehran ProvinceAges 18–45 - NCT05231265Recruiting
Lumbar surgery effect on walking complexity in chronic low back pain
This study looks at how lumbar spine surgery (fusion or artificial disc “prosthesis” on one or two levels) affects how complex your walking looks and feels. It may help doctors better understand what to expect from surgery and how it changes movement in people with long-term low back pain.
NîmesAges 18 years+ - NCT06686147Recruiting
AI analysis of movement in low back pain
This trial uses artificial intelligence to analyze how well you can move if you have chronic low back pain. It may help researchers understand movement patterns better.
DenizliAges 18–65 - NCT06709391Recruiting
Spinal fusion vs. no surgery for chronic low back pain
This trial tests whether a spinal fusion surgery is better than staying with non-surgical treatments for people with long-term, severe low back pain from worn-out discs in the lower spine. It aims to find out which approach offers better pain relief and quality of life.
GothenburgAges 25–65 - NCT06877767Recruiting
Graston vs Active Release for low back pain in women
This study compares two non-surgical hand techniques (Graston tool and Active Release Technique) to see which works better for reducing low back pain in women. If you have had low back pain for at least 3 months, you may be able to join and get free treatment.
Sialkot, Punjab ProvinceAges 25–50 - NCT06928597Recruiting
GPR therapy for chronic low back pain
This study tests a physical therapy method called Global Postural Re-education (GPR) for people with long-term low back pain that is not caused by a specific disease. It aims to see if GPR can help reduce pain and improve function.
Salvador, Estado de BahiaAges 18–55 - NCT07003113Recruiting
Blood flow therapy for knee and back pain
This study tests a treatment called ischemic preconditioning, which uses a blood pressure cuff to temporarily restrict blood flow to your leg. It may help reduce pain from osteoarthritis in the knee or chronic back pain.
Chicago, IllinoisAges 50 years+ - NCT07026058Recruiting
Sound wave therapy for mechanical low back pain
This study tests whether adding sound wave therapy to standard physical therapy helps adults with long-lasting low back pain. It is for people aged 18 to 45 whose pain stays above the knee.
Lahore, Punjab ProvinceAges 18–45 - NCT07298109Recruiting
Diaphragm Release for Chronic Low Back Pain
This study tests if releasing tension in the diaphragm muscle can help reduce chronic low back pain. It may be a treatment option for people whose back pain has lasted at least 12 weeks and has no clear cause.
KarabükAges 18–65 - NCT07332390Recruiting
Exercise study for chronic non-specific low back pain
This study compares two types of exercise programs—moderate load eccentric core exercises and Pilates—to see which is more effective for people with long-lasting low back pain that isn't caused by a specific medical condition.
Islamabad, Punjab ProvinceAges 18–45 - NCT07523906Recruiting
Exercise therapy for chronic lower back pain in young adults
This study compares two types of exercise programs for chronic mechanical lower back pain: lumbar stabilization exercises (focused on core strength) versus muscular chain therapy (full-body movement patterns). You'll participate in one of these exercise programs to see which helps reduce your pain more effectively.
IslamabadAges 18–30 - NCT07576101Recruiting
Blood Flow Restriction Training for Lower Back Pain
This study tests whether a special exercise technique that carefully reduces blood flow to your legs while exercising can help reduce chronic lower back pain. The goal is to see if this method combined with training can strengthen your muscles and relieve pain more effectively.
IslamabadAges 18–45 - NCT07603609Recruiting
Balance Platform Training for Chronic Low Back Pain
This study tests whether training on a special moving balance platform can help reduce chronic low back pain. You'll practice exercises designed to improve your balance and core stability over several weeks.
AnkaraAges 18–55 - NCT07524010Enrolling by invitation
Electrolysis Treatment for Lower Back Pain in Active Men
This study tests a needle-based treatment called percutaneous electrolysis on the muscles in your lower back to reduce pain. Researchers will analyze how your body responds to understand why it might help with back pain.
VercelliAges 18 years+ - NCT07163546Enrolling by invitation
Lifestyle redesign for chronic low back pain
This trial tests a person-centered lifestyle program to help people with chronic low back pain learn new ways to manage daily activities and reduce pain. It may be a good fit if you have had low back pain for at least 3 months and are looking for non-surgical support.
Ankara, AltındağAges 18–65 - NCT07328126Recruiting
Muscle energy technique for low back pain relief
This trial tests a gentle muscle stretching method (muscle energy technique) on the latissimus dorsi muscle to see if it reduces pain, improves daily function, and increases spine movement in people with long-term low back pain.
Rawalpindi, Punjab ProvinceAges 30–55 - NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT06310226Recruiting
Studying spinal cord stimulation for chronic low back pain
This study is looking at how people with chronic low back pain respond to spinal cord stimulation (a device that sends gentle electrical pulses to the spine to reduce pain). If you already have a spinal cord stimulator, you may help researchers understand how well it works and how it affects your brain.
Los Angeles, CaliforniaAges 18–80 - NCT06703671Recruiting
Acupuncture for disc-related low back pain
This trial tests whether electroacupuncture (a type of acupuncture with mild electric pulses) can help people with low back pain caused by a damaged disc. If you have had back pain for at least a month and have not had certain other treatments recently, you may be eligible.
Beijing, Beijing MunicipalityAges 18–70 - NCT07222462Recruiting
Radiofrequency ablation for chronic low back pain
This study tests if radiofrequency ablation, a procedure that uses heat to block pain signals from the facet joints in your spine, can help people with long-term low back pain that hasn't improved with other treatments like physical therapy.
Atlanta, GeorgiaAges 18 years+ - NCT06902233Recruiting
Brain stimulation for chronic low back pain
This trial tests if a non-invasive brain stimulation technique can help people with long-lasting low back pain. It uses mild electrical currents to adjust brain activity and may reduce pain and improve daily function.
Dunedin, OtagoAges 18–75 - NCT06828016Recruiting
Foot Reflexology for Chronic Low Back Pain
This study tests whether foot reflexology—a gentle massage of the feet—can help relieve chronic low back pain that has lasted more than 12 weeks. It is a safe, non-drug approach that may be a good option for people looking for a natural way to manage their pain.
New Taipei CityAges 18–100
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Common questions
- Are there clinical trials for lower back pain?
- Yes. Clin2 currently lists 126 recruiting lower back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lower back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lower back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.