Clinical trials
Lower Back Pain clinical trials
Below are recruiting lower back pain clinical trials, each written for real people, not researchers. We’re tracking 122 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06703671Recruiting
Acupuncture for disc-related low back pain
This trial tests whether electroacupuncture (a type of acupuncture with mild electric pulses) can help people with low back pain caused by a damaged disc. If you have had back pain for at least a month and have not had certain other treatments recently, you may be eligible.
Beijing, Beijing MunicipalityAges 18–70 - NCT06310226Recruiting
Studying spinal cord stimulation for chronic low back pain
This study is looking at how people with chronic low back pain respond to spinal cord stimulation (a device that sends gentle electrical pulses to the spine to reduce pain). If you already have a spinal cord stimulator, you may help researchers understand how well it works and how it affects your brain.
Los Angeles, CaliforniaAges 18–80 - NCT05669027Recruiting
Mobile brain training to help low back pain
This study tests whether mobile “neurofeedback” training can reduce low back pain and improve how much it affects your daily life. You would likely use sensors that measure brain and body signals to guide the training.
Durham, North CarolinaAges 18–90 - NCT05963451Recruiting
Testing treatments for long-term low back pain from facet joints
This study focuses on people with long-lasting low back pain that likely comes from the small “facet” joints in the lower spine. It aims to better understand brain, psychological, and biology changes to help optimize treatment for this type of back pain.
Sherbrooke, QuebecAges 18–75 - NCT07726797Recruiting
Pelvic control training vs core stability for low back pain
This trial compares two types of exercises — pelvic control training with a pressure sensor versus core stability training — to see which one works better for relieving low back pain. It may help if you are a young adult with no other health issues affecting your back or balance.
Lahore, Punjab ProvinceAges 18–30 - NCT07685340Recruiting
Cupping vs Massage Tool for Chronic Low Back Pain
This trial tests two hands-on therapies—dry cupping and a special massage technique—to see which works better for long-term low back pain caused by muscle knots. You may be able to join if your pain has lasted over 3 months and you have trigger points.
Rawalpindi, Punjab ProvinceAges 25–45 - NCT07675304RecruitingEarly Phase 1
Mesotherapy for chronic low back pain study
This trial tests whether injecting a natural substance (collagen) into the lower back can safely reduce chronic pain. It may help people with pain that hasn't spread to the legs.
WarsawAges 18–65 - NCT06785909Recruiting
Understanding why pregnancy back and pelvic pain persists
This study looks at why some women develop ongoing pain in the lower back or pelvis during pregnancy. It tests how your body's sense of movement, fear of pain, and inflammation might be related. You may join if you are early in a single pregnancy and do not have that pain yet.
HasseltAges 18–40 - NCT06661850Recruiting
New imaging test to guide lower back surgery decisions
This study tests a new imaging tool called Nociscan to see if it helps doctors decide who will benefit from lumbar spine surgery for low back pain. It may help predict surgical outcomes and guide treatment.
Phoenix, ArizonaAges 18–70 - NCT06517342Recruiting
Using a health app for low back pain
This study looks at what helps or stops people with chronic low back pain from using a smartphone app to become more active. It aims to find ways to make it easier for you to stay active.
Clermont-FerrandAges 18 years+ - NCT07040397Recruiting
Massage therapy study for lower back pain
This study tests whether an electronic approach to massage therapy can help relieve lower back pain. It may be an option if you have persistent lower back pain and haven't used pain medications recently.
Rochester, MinnesotaAges 18 years+ - NCT07790328Recruiting
Long-term safety of the IntraSPINE implant for low back pain
This study checks how safe and effective the IntraSPINE implant is over time for people with low back pain from degenerative discs. The implant is placed in your spine to support it, and this trial helps see if it continues working well for years.
SaranAges 18 years+ - NCT05657964Recruiting
Study of a back pain exercise program for chronic low back pain
This trial tests whether a structured exercise/education program can help people with chronic lower back pain. You may qualify if your pain and disability scores are high enough and you can complete study activities in English.
Redwood City, CaliforniaAges 18–65 - NCT06693453Recruiting
Acupuncture plus cupping for lower back pain
This study tests whether combining electronic acupuncture with dry cupping helps relieve lower back pain caused by a spine condition. It is for people whose pain matches a traditional Chinese medicine pattern of stabbing, fixed pain that gets worse at night.
Ho Chi Minh CityAges 18–70 - NCT06944730Recruiting
Trunk muscle training for better movement and balance in low back pain
This study tests whether trunk muscle training can improve the quality of your movements and balance if you have chronic low back pain. It is designed for people with moderate pain and no other major health issues.
Hong KongAges 18–55 - NCT05757609Recruiting
Brain stimulation therapy for chronic low back pain
This trial tests whether a non-invasive brain stimulation treatment can improve physiotherapy results for people with long-lasting low back pain. You may be asked to do questionnaires and follow a treatment plan, and some people may be able to reduce pain or improve function.
GenevaAges 18–65 - NCT06584721Recruiting
Foot exercises and taping for low back pain with flat feet
This study tests whether simple foot exercises combined with special tape on the foot can reduce low back pain in people whose feet roll inward too much (a condition called hyper-pronation). It may help if you have had back pain for months and also have flat feet.
Wāh, Punjab ProvinceAges 25–45 - NCT06856642Recruiting
Comparing belly drawing exercises with ultrasound for chronic back pain
This study compares two types of physical therapy for chronic low back pain: one uses real-time ultrasound to help you learn a special belly-drawing maneuver, the other is standard physical therapy. The goal is to see which method reduces pain better.
BoluAges 18–65 - NCT05832918Recruiting
Core exercises plus brain tasks for chronic low back pain
This study tests whether doing core (stability) exercises along with simple cognitive (thinking) tasks can reduce long-lasting low back pain. It may help if your pain has lasted at least 3 months and you can safely take part in exercise.
Tehran, Iran (the Islamic Republic Of)Ages 18–55 - NCT06419439RecruitingPhase 2
Ketamine for Veterans with Chronic Back Pain and Depression
This study tests whether ketamine, combined with talk therapy, can help veterans with both chronic low back pain and depression. The goal is to reduce pain and improve mood.
Ann Arbor, MichiganAges 18 years+ - NCT07636967Recruiting
Ankle Muscle Strength in Chronic Low Back Pain
This study measures the strength and function of ankle muscles in people with chronic low back pain lasting over 3 months. Understanding how ankle muscles work may help explain why some people develop long-term low back pain.
Tanta, Gharbia GovernorateAges 20–25 - NCT07296653RecruitingEarly Phase 1
Prolotherapy for chronic low back pain
This trial tests a treatment called prolotherapy, which uses injections of a sugar solution into specific acupuncture points to help relieve chronic low back pain. It is for people who have had low back pain for at least 3 months, have not had previous back surgery, and have not received similar injections recently.
Athens, AtticaAges 35 years+ - NCT04226716Recruiting
Studying pelvic pain causes in multiple or first pregnancies
This study looks at why pelvic girdle pain happens during pregnancy, focusing on body sensing (proprioception), stress factors, and inflammation. You may be able to help researchers understand the causes and who is most at risk.
HasseltAges 18–40 - NCT07693998Enrolling by invitation
Pain education class for fibromyalgia or chronic back pain
This trial tests a class to help people with fibromyalgia or chronic low back pain learn about their pain and how to manage it. It might help you feel better and understand your pain.
Valencia, ValenciaAges 18 years+
Hear when a new Lower Back Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for lower back pain?
- Yes. Clin2 currently lists 122 recruiting lower back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lower back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lower back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.