Clinical trials
Lung clinical trials
Below are recruiting lung clinical trials, each written for real people, not researchers. We’re tracking 2,828 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05974475Recruiting
Personalized modeling during targeted lung radiation for early cancer
This trial studies how detailed tests (“multi-omics” modeling) can improve how doctors plan and deliver stereotactic body radiotherapy (SBRT) for early-stage non-small cell lung cancer. It may help make treatment planning more precise for cancers in stages I–II.
Milan, ItalyAges 18 years+ - NCT07742332RecruitingPhase 2
Targeted therapy before surgery for EGFR-mutant lung cancer
This trial tests a combination of two targeted medicines (befotertinib and bevacizumab) before surgery for people with EGFR-mutant non-small cell lung cancer that cannot be removed right away. The goal is to see if this treatment can shrink the tumor and improve surgery outcomes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07744529RecruitingPhase 1/Phase 2
Combination treatment for lung cancer spread to the lining of the brain
This trial tests a new combination of two drugs for people with a specific type of lung cancer that has spread to the lining of the brain and spinal cord. The treatment aims to target the cancer cells and may help improve symptoms and survival.
Hangzhou, ZhejiangAges 18 years+ - NCT06247163Recruiting
PET-guided radiation for small cell lung cancer
This trial uses PET scans to guide radiotherapy for people with limited-stage small cell lung cancer, aiming to improve treatment accuracy. It is designed for those whose cancer has not spread extensively.
EssenAges 18 years+ - NCT06623487Recruiting
PET scan to guide immunotherapy for stage III lung cancer
This trial uses a special scan (68Ga-grazytracer PET) to see how well immunotherapy works for stage III non-small cell lung cancer before surgery or radiation. It aims to help doctors choose the best treatment for you.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06626178Recruiting
AI for preventing smoking-related diseases
This study uses artificial intelligence to analyze CT scans and other health data to better identify people at risk for smoking-related diseases like lung cancer. Researchers hope to improve early detection and prevention.
MilanAges 18 years+ - NCT07727681RecruitingPhase 4
Statins to Prevent Atrial Fibrillation After Lung Surgery
This trial tests whether taking a statin before and after lung surgery can prevent a common heart rhythm problem called atrial fibrillation (AFib). If you are 60 or older and having a lung segment or lobe removed, this study may help you avoid AFib after your operation.
BeijingAges 60 years+ - NCT06628102Recruiting
Breath test for early lung cancer detection
This study tests a breath test to detect lung cancer early in people with a lung nodule found on a CT scan. It aims to improve detection in diverse populations.
Vancouver, British ColumbiaAges 50–80 - NCT07723482RecruitingPhase 1/Phase 2
Study of ML-016 for cancer that has spread to lungs or liver
This trial tests a new drug called ML-016 in people whose advanced cancer has spread to their lungs or liver and who have run out of standard treatment options. The goal is to see if ML-016 can shrink tumors or slow the cancer's growth.
Miranda, New South WalesAges 18 years+ - NCT07716527Enrolling by invitation
Testing a web tool for lung cancer screening
This study is testing a new website-based tool to help people decide if they should get screened for lung cancer. You may be eligible if you are between 50 and 80 years old and currently smoke or recently quit.
New Brunswick, New JerseyAges 50–80 - NCT07716280Recruiting
Text message help for lung cancer screening in safety-net clinics
This study tests if text messages can help people who are at risk for lung cancer get screened. If you are a current or former smoker between 50 and 80 years old, and speak English or Spanish, this may help remind you or guide you to get a lung cancer check.
Salt Lake City, UtahAges 50–80 - NCT07715617Recruiting
Creating a prediction score for lung transplant or death in Alpha-1 Antitrypsin Deficiency
This study is creating a simple scoring system to predict who with Alpha-1 Antitrypsin Deficiency-related emphysema might need a lung transplant or die from the disease. Your medical records from 2010–2025 will help build this tool, with no extra tests or visits required.
BronAges 18 years+ - NCT06634966RecruitingPhase 3
Lung cancer surgery study for specific nodule types
This trial is testing a lung-sparing surgery called segmentectomy for people with a certain type of lung cancer nodule. It aims to see if this surgery is a good option for those with solid-dominant nodules that are 2 to 3 cm in size and have not spread to lymph nodes.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05487391RecruitingPhase 3
QL1706 plus chemo after lung cancer surgery
This trial studies whether a study drug called QL1706 added to standard platinum chemotherapy can lower the chance of lung cancer coming back after surgery. It targets people with stage II to IIIB non-small cell lung cancer who have had their tumor fully removed.
ShanghaiAges 18 years+ - NCT05902559Recruiting
Study of new lung-check biomarkers in older adults
This study looks at new blood or test “biomarkers” to understand how well targeted lung health checks work. You join if you’re already attending the NHS lung health check program and can consent.
LondonAges 55–74 - NCT06607770RecruitingPhase 1/Phase 2
Cryoablation with immunotherapy for multiple lung cancers
This trial tests freezing tumors (cryoablation) combined with two drugs (Karelizumab and Apatinib) for people who have several small lung cancer spots in their lungs but no spread to lymph nodes. The goal is to see if this combination is safe and helps shrink or control the tumors.
Guangzhou, GuangdongAges 18–75 - NCT06638528Recruiting
Can Walking and Breath-Holding Reduce Pain Sensitivity?
This study tests a special breathing technique called 'walking apnea' (holding your breath while walking) to see if it can reduce pain sensitivity. Healthy volunteers will do this exercise, and researchers will measure how it affects your pain perception.
MadridAges 18–65 - NCT06638515Recruiting
Walking and breathing exercise for pain relief
This study tests whether a specific breathing exercise (walking while breathing at a low lung volume) can reduce pain sensitivity. It's looking for healthy people who have no ongoing medical conditions or pain.
MadridAges 18–65 - NCT06498479RecruitingPhase 3
Comparing a new drug to topotecan for relapsed small cell lung cancer
This trial tests a new drug called HS-20093 against a standard drug (topotecan) for people with small cell lung cancer that has returned after initial treatment. The goal is to see which drug works better.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04605146Recruiting
Telemonitoring to manage side effects from immunotherapy
This trial tests whether using home digital monitoring (telemonitoring) can help people with melanoma, lung, or kidney (renal) cancer manage side effects while on immunotherapy. It may help catch side effects earlier and support you during treatment with nivolumab plus ipilimumab or nivolumab alone.
BronAges 18 years+ - NCT07699328RecruitingPhase 1/Phase 2
Study of VRN110755 for EGFR-mutant lung cancer
This trial tests a new oral targeted therapy (VRN110755) for people with EGFR-mutant lung cancer. It is for those whose cancer has advanced or spread, and who either have not been treated yet or who stopped responding to previous EGFR pills.
Bedford Park, South AustraliaAges 18 years+ - NCT06645977Recruiting
Study for patients with interstitial lung disease
This trial is for adults with interstitial lung disease (a group of lung conditions that cause scarring). It aims to understand the disease better and may help find new ways to treat it.
Rome, RMAges 18 years+ - NCT07701733Recruiting
Lung cancer risk study for women who never smoked
This study looks at lung cancer risk in women who have never smoked. It aims to understand why some never-smokers develop lung cancer while others don't.
Basking Ridge, New JerseyAges 40–74 - NCT06182748Recruiting
Physical activity and lung scarring
This study tests if a supervised exercise program, 3 times a week, helps people with lung scarring (fibrosing interstitial lung disease). It may improve your breathing and quality of life.
Bobigny, Seine Saint DenisAges 18 years+
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Common questions
- Are there clinical trials for lung?
- Yes. Clin2 currently lists 2,828 recruiting lung studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.