Clinical trials
Lung clinical trials
Below are recruiting lung clinical trials, each written for real people, not researchers. We’re tracking 2,907 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05568212RecruitingPhase 2
Trial of immune combination versus standard care for NSCLC relapse
This Phase 2 trial studies an immune-based drug combination compared with standard care for lung cancer that has come back after chemoradiation and durvalumab. It aims to improve control of the cancer after durvalumab is no longer working.
Roma, RMAges 18 years+ - NCT07379242Recruiting
Lung recruitment test for breathing failure patients on a ventilator
This trial uses a special imaging technique (electrical impedance tomography) to find the best ventilator settings for patients with acute breathing failure. It may help doctors tailor treatment to improve lung function.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07362342Recruiting
Right heart function after lung lobe removal surgery
This study looks at how the right side of the heart handles the stress of having a lung lobe removed. It compares different surgery types (VATS, robotic, or open) and focuses on people with moderate to high heart and lung risk factors.
Rozzano, MIAges 18 years+ - NCT06362252RecruitingPhase 1/Phase 2
I-DXd plus atezolizumab for first-line extensive SCLC
This trial tests a new combination of drugs (I-DXd and atezolizumab, with or without carboplatin) as your first treatment for extensive stage small cell lung cancer. It has two groups: one for people who haven't started treatment yet, and another for those who've already had 4 cycles of a standard chemo-immunotherapy combination and are stable or better.
Birmingham, AlabamaAges 18 years+ - NCT06945120Recruiting
Lung Health Program for Chinese and Korean Smokers
This study is testing a program to help Chinese and Korean adults who smoke to improve their lung health. You may be able to join if you are a current smoker, speak Korean, Mandarin, or English, and live in the U.S.
Boston, MassachusettsAges 18–100 - NCT05701176Recruiting
Imaging scan to see how anti–PD-1 changes lung cancer cells
This study uses special PET imaging to measure changes in a marker ([18F]F-AraG) in non-small cell lung cancer after starting anti–PD-1 treatment. It aims to learn whether these scan changes reflect how the cancer responds.
AmsterdamAges 18 years+ - NCT07325773Recruiting
Can magnesium help lung function during one-lung breathing?
This trial tests if giving magnesium during surgery helps oxygen levels in the blood and supports lung mechanics when only one lung is used for breathing.
IstanbulAges 18–80 - NCT06903117RecruitingPhase 1
CAR T-Cell Therapy for CEA-Positive Advanced Lung Cancer
This early-stage trial tests a special immune cell treatment (CAR T cells) designed to target and attack lung cancer cells that have a protein called CEA on their surface. It's for people with advanced lung cancer who have already tried at least two standard treatments without success.
ShanghaiAges 18 years+ - NCT06603350Recruiting
How surgery factors affect recovery after lung transplant
This study looks at how things before, during, and right after lung transplant surgery affect recovery. Researchers want to learn what helps patients heal better so they can improve care.
Hangzhou, ZhejiangAges 18 years+ - NCT07309276RecruitingPhase 2
Study of JS212 for advanced lung cancer
This trial tests a new drug called JS212 combined with other treatments for people with advanced or spreading lung cancer. It aims to see if the combination can help shrink tumors or slow the disease.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05889247Recruiting
Blood test guided monitoring for advanced lung cancer treatment
This trial checks whether a blood test that looks for cancer DNA can help guide and monitor treatment in people with advanced non-small cell lung cancer (NSCLC). It may help your team spot treatment response or changes earlier, so care can be adjusted appropriately.
Hillerød, Region HAges Any age - NCT04616313Recruiting
MRI and breathing tests in people who vape
This study uses a special lung scan (MRI) and breathing tests to understand how vaping affects lung structure and function. It may help researchers learn what early lung changes happen after starting vaping, even if you don’t feel sick.
London, OntarioAges 16 years+ - NCT07388680RecruitingPhase 2/Phase 3
Pirfenidone for radiation lung injury with or without immune pneumonia
This trial tests if pirfenidone capsules can help treat lung damage caused by radiation therapy, with or without immune-related pneumonia. It may be suitable for people with mild to moderate lung function impairment who have recently developed radiation lung injury.
Hefei, AnhuiAges 18–75 - NCT06483282RecruitingPhase 2
Study of immunotherapy plus targeted therapy and chemo before surgery for lung cancer
This trial tests a combination of immunotherapy (adebrelimab), a targeted therapy (apatinib), and chemotherapy given before surgery for people with limited-stage small cell lung cancer. The goal is to see if this treatment shrinks the tumor enough to make surgery more effective and to study markers that might predict response.
Hangzhou, ZhejiangAges 18–75 - NCT07517692Enrolling by invitation
Improving shared decision-making for lung cancer screening
This study tests a new way to help patients and doctors discuss lung cancer screening together using text messages and shared decision-making tools. It may help you understand screening options better and make choices that fit your values.
Worcester, MassachusettsAges 50–77 - NCT05053802RecruitingPhase 2
Microwave tumor ablation plus immunotherapy for multiple lung cancers
This Phase 2 trial studies whether combining microwave ablation (a procedure to destroy lung tumors) with an immune checkpoint inhibitor can control multiple early lung cancers safely. It also aims to see how well the immune treatment helps after ablation, in people whose cancers have not spread.
Shanghai, Shanghai MunicipalityAges 18–79 - NCT06824402Recruiting
Cryoprobe Biopsy for Chronic Rejection in Lung Transplant
This trial tests a new biopsy method called cryoprobe (using a cold probe) to better detect chronic rejection in lung transplant patients. It is for patients who already need a lung biopsy, either for routine monitoring or because of a concern.
Rochester, MinnesotaAges 18–99 - NCT06924515Enrolling by invitation
Intercostal suturing to prevent lung hernia after chest surgery
This trial tests whether a special stitch between the ribs during lung surgery can prevent a rare complication where lung tissue bulges out of the chest wall. It is for people having lung surgery through several small incisions.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT07235683RecruitingPhase 4
Stronger CMV treatment for lung transplant recipients
This trial tests adding a drug called letermovir to standard antiviral therapy for lung transplant patients with CMV infection. The goal is to see if the combination helps clear the virus faster and more effectively.
Toronto, OntarioAges 18 years+ - NCT05692999RecruitingPhase 3
Maintenance pembrolizumab dose study for non-squamous lung cancer
This Phase 3 trial tests two maintenance schedules (“usual” dose versus a lower dose) of pembrolizumab after your initial chemotherapy with pembrolizumab. It aims to see if the lower dose works well enough to control cancer while possibly reducing side effects.
NamurAges 18 years+ - NCT07207278Recruiting
Genetics and immune study of lung signet ring cell cancer
This research study is looking at the unique genetic makeup and immune features of a rare type of lung cancer called signet ring cell carcinoma. By studying tumor samples and medical data, researchers hope to find better ways to understand and eventually treat this cancer.
Hangzhou, ZhejiangAges 18–85 - NCT06513091Recruiting
National lung transplant recipient registry study
This study collects information from all lung transplant recipients in the United States to track their health and outcomes over time. It helps doctors learn how to improve care for people who have had a lung transplant.
Phoenix, ArizonaAges Any age - NCT05678166Recruiting
Testing a blood marker to predict worsening lung mycobacterial disease
This study checks whether a blood test called soluble programmed death-1 can help predict how nodular-bronchiectatic nontuberculous mycobacterial (NTM) lung disease will progress. Results may help doctors monitor patients more accurately and decide when to treat or follow more closely.
TaipeiAges 20 years+ - NCT07392086Recruiting
Comparing two types of ventilation during one-lung surgery
This trial compares two ways of helping you breathe during chest surgery: flow-controlled ventilation and volume-controlled ventilation. The goal is to see which method works better for oxygen and lung protection while one lung is temporarily deflated.
Ankara, YenimahalleAges 18–80
Hear when a new Lung trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for lung?
- Yes. Clin2 currently lists 2,907 recruiting lung studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.