Clinical trials
Lymph Node Metastasis clinical trials
Below are recruiting lymph node metastasis clinical trials, each written for real people, not researchers. We’re tracking 118 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06840418Recruiting
New imaging to find cancer spread in cervical cancer surgery
This study tests a new imaging technique (NIRFI with ICG dye) to help surgeons see if cervical cancer has spread to lymph nodes during your hysterectomy surgery. It may help guide more precise removal of affected nodes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07040657Recruiting
Comparing injection techniques for cervical lymph node mapping in endometrial cancer
This trial tests two different injection methods in the cervix to help map lymph nodes for endometrial cancer. The goal is to find which technique works better for staging, using a dye that helps surgeons see the lymph nodes during surgery.
AnkaraAges 18–75 - NCT07050576Recruiting
Lymph node spread in early esophageal cancer
This trial looks at how early-stage esophageal cancer spreads to lymph nodes. It uses CT scans and pathology reports to understand patterns, which may help guide future treatment decisions.
Hefei, AnhuiAges Any age - NCT07112599Recruiting
AI predicts lymph node spread in high-risk prostate cancer
This study uses artificial intelligence to examine MRI and other health data to better predict if high-risk prostate cancer has spread to nearby lymph nodes. Researchers hope this will help guide treatment decisions.
Hefei, AnhuiAges 50 years+ - NCT07146295Recruiting
ICG dye to find sentinel nodes in breast cancer surgery
This trial tests using a green dye called ICG (indocyanine green) during breast cancer surgery to find the first lymph nodes (sentinel nodes) that cancer may have spread to. It aims to help doctors locate these nodes more accurately, and is for people with early-stage breast cancer that has not yet spread to the lymph nodes.
AlkmaarAges 18 years+ - NCT07154563Recruiting
Quick test for breast cancer spread to lymph nodes using a new probe
This trial uses a special probe that lights up cancer cells to quickly check if breast cancer has spread to nearby lymph nodes. It may help doctors decide how much surgery is needed.
Kunming, YunnanAges 18–75 - NCT07155954Recruiting
Super-Resolution Ultrasound to Tell Benign from Malignant Lymph Nodes
This study uses a special high-detail ultrasound technique to better tell if lymph nodes are harmless (benign) or cancerous (malignant). It may help avoid unnecessary biopsies or surgeries in the future.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07362485Recruiting
Finding sentinel nodes during mastectomy with dye
This trial tests if a special dye (indocyanine green) can find the first lymph nodes (sentinel nodes) during mastectomy. It may help improve staging for women with early breast cancer who need or choose mastectomy.
Zwolle, OverijsselAges 18 years+ - NCT06957678Enrolling by invitation
AI predicts lymph node spread in stomach cancer using scans and biopsy
This study uses artificial intelligence to predict whether stomach cancer has spread to nearby lymph nodes. By analyzing your CT/MRI scans and biopsy results before surgery, the AI may help doctors plan your treatment more precisely.
Shijiazhuang, None SelectedAges 18–80 - NCT06947096Enrolling by invitation
AI prediction of stomach cancer spread to lymph nodes
This study uses artificial intelligence to analyze your CT scan and predict whether stomach cancer has spread to lymph nodes behind your belly. The goal is to help doctors decide if you need more extensive surgery.
Shijiazhuang, None SelectedAges 18–80 - NCT06883084Enrolling by invitation
How lymph node changes affect rectal cancer outcomes
This trial looks at how much the lymph nodes respond to chemoradiation before surgery in people with locally advanced rectal cancer. It aims to understand if that response can predict long-term results and guide future treatment choices.
Ages 18–65 - NCT07415356Recruiting
Adaptive radiation for lymph node tumors that have spread
This trial tests a new way to deliver targeted radiation for cancer that has spread to lymph nodes in the belly or pelvis. The radiation dose is adjusted during each session to better hit the tumor while protecting healthy tissue.
Rotterdam, South HollandAges 18 years+ - NCT05935150Recruiting
Skipping lymph node surgery in early breast cancer
This trial studies whether you can safely avoid a lymph node biopsy in the armpit for early breast cancer when scans and exams look negative. It may reduce surgery-related side effects while still keeping cancer care on track.
Nanjing, JiangsuAges 18–70 - NCT06146946Recruiting
Rectal cancer surgery trial: Skipping certain lymph node removal
This trial is testing whether a more limited surgery for mid and low rectal cancer can be safe, by avoiding removal of lymph nodes near the main artery. It may be a good fit if your tumor is in the lower rectum, hasn't spread far, and you are in generally good health.
Beijing, Beijing MunicipalityAges 18–75 - NCT06468696Recruiting
Scarless thyroid surgery study
This trial is testing a specific type of scarless thyroid surgery (through the chest) and seeing how well it works for people with thyroid tumors that haven't spread. It might be a good fit if you want to avoid a neck scar.
Xi'an, ShaanxiAges 18–75 - NCT06652672Recruiting
Sentinel Node and Organ-Sparing Surgery for Early Colon Cancer
This trial tests a less invasive surgery approach for early-stage colon cancer. It uses a special dye to find and remove only the first lymph node (sentinel node) while removing just the part of the colon with the tumor, possibly avoiding a bigger surgery.
AmersfoortAges 18 years+ - NCT07049276Recruiting
Lymph node surgery for melanoma with immunotherapy
This trial tests if a specific type of lymph node surgery, combined with a short course of immunotherapy (medicines that help your immune system fight cancer), works better for melanoma that has spread to nearby lymph nodes. It's for people whose melanoma can be removed and who are healthy enough for treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT03385018Recruiting
Laparoscopic total stomach surgery trial for stomach cancer
This trial studies whether a minimally invasive (laparoscopic) removal of the entire stomach, along with lymph node removal, can be done safely and effectively for certain stomach cancers. It may be an option if your cancer is in the stomach, has limited spread to nearby lymph nodes, and can be fully removed.
SeoulAges 20–80 - NCT03796559Recruiting
Magnetic marker helps find breast cancer lymph nodes
This study uses a tiny magnetic marker (called Magseed) placed in a breast cancer–affected underarm lymph node, then tracks whether surgeons can find and remove the correct nodes after chemotherapy. It may help reduce the chance of missing cancer in the underarm while aiming for more accurate surgery.
Houston, TexasAges 18 years+ - NCT04109079Recruiting
Best surgery plan for breast cancer lymph nodes after chemotherapy
This study looks at the safest and most useful way to remove and check breast-cancer lymph nodes in the armpit after you finish chemotherapy given before surgery. It may help you avoid unnecessary surgery while still getting accurate information about how well the treatment worked.
DublinAges 18 years+ - NCT05981014RecruitingPhase 1/Phase 2
Immune cells from lymph nodes for HER2-negative breast cancer
This trial tests whether taking immune cells from your lymph nodes and giving them back to you can help shrink breast cancer that has not responded fully to initial chemotherapy. It is for women with HER2-negative breast cancer who have had stable disease after two cycles of a standard chemotherapy combination.
Guangzhou, GuangdongAges 18–70 - NCT06121570RecruitingPhase 1
Study of immune cells from lymph nodes for HER2-negative breast cancer
This trial tests whether using a patient's own immune cells from lymph nodes near the tumor, given as a treatment before surgery, can help shrink HER2-negative breast cancer. It is for people whose cancer has not responded fully to two cycles of initial chemotherapy.
Guangzhou, GuangdongAges 18–70 - NCT06831032Recruiting
Adaptive radiation for prostate cancer in lymph nodes
This trial tests a type of targeted radiation (SBRT) for prostate cancer that has come back only in certain lymph nodes around the belly or hip. The goal is to see if adapting the radiation plan during treatment can make the response last longer.
Toronto, OntarioAges 18 years+ - NCT05132283Recruiting
Lymph node removal for urologic cancers with advanced imaging
This study uses a special MRI scanner in the operating room to help guide lymph node removal during surgery for urologic cancers like bladder, prostate, testicular, kidney, urethral, or penile cancer. It aims to see if this real-time imaging can make the surgery more precise.
Boston, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for lymph node metastasis?
- Yes. Clin2 currently lists 118 recruiting lymph node metastasis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lymph node metastasis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lymph node metastasis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.