Clinical trials
Male clinical trials
Below are recruiting male clinical trials, each written for real people, not researchers. We’re tracking 233 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03803332Recruiting
Therapies for PTSD from military sexual trauma compared for adults
This trial compares two types of talk therapy to treat PTSD caused by military sexual trauma. It aims to see which therapy helps symptoms better and how well people can complete weekly outpatient sessions.
New York, New YorkAges 18–85 - NCT03851627RecruitingPhase 4
Testosterone for fatty liver in overweight men with diabetes
This trial compares testosterone undecanoate versus a placebo (inactive pill) to see if it lowers fat in the liver measured by MRI. It focuses on overweight or obese men who have prediabetes or type 2 diabetes and low testosterone confirmed by blood tests.
ViennaAges 18–75 - NCT04064671Recruiting
Study of a specific erectile implant after sex reassignment surgery
This study looks at surgical outcomes after placing the Zephyr ZSI 475 FTM inflatable penile implant in people who had female-to-male (transmasculine) sex reassignment surgery. It may help improve how well this specific implant works and how patients do after surgery.
Ghent, Oost-VlaanderenAges 18–100 - NCT04342026Recruiting
Study environment and hormones in undescended testicles
This study looks at whether environmental exposures and hormone disruption are linked to undescended testicles in children. It may help researchers better understand causes and risk factors, which could improve future care for affected families.
MontpellierAges 1 month–18 years - NCT04452305Recruiting
Frozen testicle tissue transplant to restore fertility
This study tests using previously frozen (cryopreserved) testicle cells or tissue to regrow testicular tissue. If you’ve had cancer treatment that can harm fertility, this may help restore natural fertility potential using your own tissue.
Pittsburgh, PennsylvaniaAges Any age - NCT04460872RecruitingPhase 2
Testosterone plus walking training to support bones and muscles
This Phase 2 study tests whether testosterone therapy combined with walking training can improve bone and muscle health after a spinal cord injury. It aims to help men with low testosterone and walking problems by improving strength, body composition, and related health markers.
Gainesville, FloridaAges 18 years+ - NCT04526353RecruitingPhase 2
Oxybutynin for young boys with posterior urethral valves
This trial tests whether early use of oxybutynin can improve bladder and urine behavior in very young boys with posterior urethral valves. It is mainly for babies whose bladder tests show problems even after valve surgery.
BordeauxAges 3 months–6 months - NCT04740541Recruiting
Diet study for adult men with Crohn’s disease
This study looks at how a specific amino-acid (threonine) diet affects adults with Crohn’s disease and signs of intestinal inflammation. It may help researchers understand what dietary protein needs could support more stable disease.
Toronto, OntarioAges 18–49 - NCT04760574Recruiting
HIV status and low testosterone in men
This study looks at whether low testosterone (often called male hypogonadism) is linked to having HIV. It compares HIV-positive men with HIV-negative men to better understand what contributes to hormone problems and how common they are.
TaipeiAges 20 years+ - NCT04798469RecruitingPhase 2
Testosterone to reduce long-term spine pain in men on opioids
This Phase 2 study tests whether taking testosterone can lessen chronic non-cancer spinal pain in men who have low testosterone while using opioid pain medicines. It may help by improving hormone levels that could be affecting pain and overall wellbeing.
Boston, MassachusettsAges 18 years+ - NCT04959864Recruiting
Food supplement study for sperm DNA damage in men
This trial tests whether a daily food supplement (with myo-inositol, N-acetyl-cysteine, zinc, and vitamins) can reduce sperm DNA damage. It enrolls men with higher-than-normal sperm DNA fragmentation, and it checks semen health during the study.
ParisAges 20–45 - NCT04980638RecruitingPhase 2
Check ER004 given in the womb for a genetic tooth-skin disorder
This Phase 2 study tests ER004 put into the amniotic fluid during pregnancy to treat male babies with X-linked hypohidrotic ectodermal dysplasia (XLHED). It also looks at effects in affected male relatives with the same gene change.
Los Angeles, CaliforniaAges 18 years+ - NCT05249634RecruitingPhase 2
Testosterone treatment study for men with chronic kidney disease
This Phase 2 study tests whether testosterone therapy can help men with chronic kidney disease who have low testosterone and related symptoms. It looks to see if treatment is safe and beneficial, while carefully checking heart, blood, prostate, and clotting risks.
St Louis, MissouriAges 18–85 - NCT05378347Recruiting
Compare two aortic stent graft types for AAA
This study compares two commercially used stent graft devices to treat an enlarged abdominal aorta (AAA). It aims to see which device works better and is safer over follow-up visits.
Loma Linda, CaliforniaAges 20 years+ - NCT05410782Recruiting
Prenatal supplements to improve sperm quality
This study tests whether a prenatal supplement for men can improve sperm quality in people trying to conceive. It focuses on improving semen results when there is low count, weaker movement, or abnormal shape.
Mississauga, OntarioAges 18–45 - NCT05479474Recruiting
PRP treatment study for men with testicular infertility
This trial studies whether platelet-rich plasma (PRP) can improve fertility in men with a specific cause of infertility called NOA who have not had success with prior procedures. It may help improve the chance of getting usable sperm for conception.
Stanford, CaliforniaAges 18 years+ - NCT05514223Recruiting
Testing sperm samples to understand lifestyle, gut, and sperm quality
This study measures “free radicals” in sperm to see how lifestyle and the microbiota (gut/community of microbes) may relate to sperm health. You may be asked to provide a semen sample as part of standard fertility testing, unless certain health factors apply.
Groningen, Provincie GroningenAges 18–55 - NCT05620940RecruitingPhase 1
IV drug safety and absorption study in healthy men
This Phase 1 study tests two experimental medicines given by IV to healthy men. It checks safety and how the body absorbs and processes the drugs (their “pharmacokinetic” profile).
Herston, QueenslandAges 18–55 - NCT05628987Recruiting
Gut bacteria study in men with sperm production problems
This trial looks at whether gut bacteria (microbiome) and lifestyle factors are linked to poor sperm production or sperm quality. You may be asked for stool, urine, and blood samples and to complete questionnaires about diet and habits to help researchers understand possible connections.
Guangzhou, GuangdongAges 18–45 - NCT05874375Recruiting
Study for overactive bladder symptoms in men
This trial looks at a treatment for overactive bladder in adult men. If you qualify, you may be asked to follow study instructions and report symptom changes during treatment.
MaastrichtAges 18 years+ - NCT05903859RecruitingPhase 3
Study to improve fertility in men after spinal cord injury
This phase 3 study tests a treatment to improve reproductive function (fertility-related measures) in men who have had a traumatic spinal cord injury. If you may be eligible, it could help researchers see whether the treatment improves reproductive outcomes for men with spinal cord injury.
Miami, FloridaAges 18 years+ - NCT05911750Recruiting
HPV study in men with Crohn’s or ulcerative colitis
This study looks at how common human papillomavirus (HPV) is in men with Crohn’s disease or ulcerative colitis and what it may mean for health. You would answer questions and provide biology samples so researchers can understand the link, if any, between HPV and bowel disease.
BarcelonaAges 18–79 - NCT05963711Recruiting
Study penis microbiome in partners during vaginal microbiome treatment
This study looks at how the bacteria on a man’s penis may change during a woman’s vaginal microbiome transplant (VMT) for recurrent bacterial vaginosis (BV). You may be asked to follow condom and “decolonization” steps to help the researchers understand what works and why.
JerusalemAges 18 years+ - NCT06045702Recruiting
Study of CFTR gene in epididymal cells from surgery
This study collects a small tissue sample from the epididymis during planned surgery. The sample is used to study how the CFTR gene works, which may help understand fertility problems in men with cystic fibrosis.
BrestAges 18 years+
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Common questions
- Are there clinical trials for male?
- Yes. Clin2 currently lists 233 recruiting male studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a male trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a male trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.