Clinical trials
Malignancy clinical trials
Below are recruiting malignancy clinical trials, each written for real people, not researchers. We’re tracking 1,543 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07612917Recruiting
Brain Activity Changes in Glioma Patients During Treatment
This study tracks how brain activity and connections change in patients with gliomas (brain tumors) as they receive treatment. Researchers use special brain scans to understand how treatment affects the brain's function, which may help improve care for glioma patients in the future.
Linz, Upper AustriaAges 18–64 - NCT07619599RecruitingPhase 1
PET Scan to Track Lung Cancer Treatment Response
This study uses a special PET imaging scan to help doctors see how well pembrolizumab (an immunotherapy drug) is working against advanced non-small cell lung cancer. You'll receive the scan along with your regular pembrolizumab treatment and possible radiation therapy to help measure treatment response.
Duarte, CaliforniaAges 18 years+ - NCT07617727RecruitingPhase 1
A study of an experimental drug for advanced solid tumors
This trial tests a new drug, JSKN021, for people with advanced solid tumors that have not responded to standard treatments, are not tolerated to them, or have no standard options. The goal is to see if the drug is safe and effective in treating these cancers.
Fuzhou, FujianAges 18–75 - NCT07613723RecruitingPhase 1
Testing ZI-MA4-1 immunotherapy for advanced solid cancers
This early-stage trial tests a new type of immunotherapy called ZI-MA4-1 in patients with advanced cancers (ovarian, lung, synovial sarcoma, or head and neck) that have stopped responding to standard treatments. The therapy is designed to help your immune system recognize and fight cancer cells that have a specific protein called MAGE-A4.
LondonAges 18–75 - NCT05718726Recruiting
Study of infections after spleen removal surgery
This trial looks at what happens after surgery to remove the spleen in people who also have major cancer surgery through the belly. It may help reduce or better manage serious infections after this kind of operation.
Basingstoke, HampshireAges 18–79 - NCT07610941RecruitingPhase 1
Testing a new cancer drug alone and combined with others
This early-stage trial tests a new experimental drug (MST-0312) in people with solid tumors like lung cancer, melanoma, bladder cancer, colorectal cancer, or triple-negative breast cancer. The goal is to find safe doses and see how well it works, either by itself or paired with other treatments.
BarcelonaAges 18 years+ - NCT07609862RecruitingPhase 1/Phase 2
Rocbrutinib and Lacutoclax for B-Cell Blood Cancers
This trial tests a combination of two new drugs (rocbrutinib and lacutoclax) to treat B-cell lymphomas and leukemias. The goal is to see if this combination works better than standard treatments, especially for patients whose cancer has come back or stopped responding to previous therapy.
TianjinAges 18 years+ - NCT07609641Recruiting
Surgery for Bile Duct Cancer: Two Surgical Approaches
This trial compares two different surgical approaches for treating bile duct cancer (cholangiocarcinoma) to see which method works better and is safer. You would undergo surgery and have your recovery and outcomes closely monitored.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07609485Recruiting
Understanding Why CAR-T Cell Therapy Works or Fails
This study collects blood and tissue samples from adults receiving CAR-T cell therapy (an advanced cancer treatment) to understand why it works well for some patients but not others. The goal is to find biological markers that predict treatment success.
LilleAges 18 years+ - NCT06172595RecruitingPhase 2
PET scan to tell tumor growth from treatment effects in brain cancer
This trial tests whether a special PET scan can tell the difference between actual tumor growth and treatment-related changes in people with aggressive brain cancer (high-grade glioma). If you have had radiation and an MRI shows a growing lesion, this study may help clarify the cause.
SingaporeAges 21 years+ - NCT07600749RecruitingPhase 1
MK-4884 study for advanced solid tumors
This early-stage study tests a new drug called MK-4884 in patients with advanced cancers that have spread. The trial includes colorectal, kidney, lung, and bile duct cancers, and aims to find the right dose and see if the drug helps shrink tumors.
St Louis, MissouriAges 18 years+ - NCT07602569Recruiting
New PET Scan for Finding Cancers More Accurately
This study tests a new type of PET scan (a special imaging test) called 18F-FGIn to help doctors better detect and evaluate cancers. It may be more accurate than the standard PET scan for certain tumors like brain, liver, stomach, and colon cancers.
GuangzhouAges 18–70 - NCT05918445RecruitingPhase 1/Phase 2
PM8002 for advanced solid tumors that have stopped responding
This Phase 1/2 study tests PM8002 in people with advanced solid cancers to see if it can work and is safe. It may help if your cancer has measurable disease and you have not fully recovered from side effects of prior treatment.
BaojiAges 18–75 - NCT06016075Recruiting
Studying kidney masses with advanced MRI
This study uses advanced MRI scans to better understand the differences between non-cancerous and cancerous kidney growths. It may help doctors improve how they diagnose and treat kidney masses.
Cambridge, CambridgeshireAges 18 years+ - NCT06720324RecruitingPhase 1/Phase 2
CD7-targeted CAR-T therapy for relapsed blood cancers
This trial tests a new type of immune cell therapy (CAR-T cells) that targets a specific marker called CD7 on blood cancer cells. It is for people whose blood cancer has not responded to other treatments or has come back after treatment.
Wuhan, HubeiAges 3–75 - NCT06538610Recruiting
Portable heart monitor for people on FOLFOX chemo
This study will use a small portable heart monitor (Holter) to track your heart rhythm while you receive FOLFOX chemotherapy. The goal is to learn more about how the chemotherapy drug 5-FU affects the heart.
AucklandAges 18 years+ - NCT07584889RecruitingPhase 1/Phase 2
CAR-T Cell Therapy for Relapsed Blood Cancers
This trial tests a new type of immune cell therapy (CAR-T cells) designed to fight blood cancers that have come back or stopped responding to standard treatments. The therapy uses your own immune cells, which are modified in a lab to better recognize and attack cancer cells.
Shenzhen, Other (Non U.s.)Ages 18–75 - NCT05733156Recruiting
Low-dose radiation to trigger whole-body cancer effects
This trial tests whether giving a low dose of radiation to one spot can help shrink cancer in other, untreated areas (the “abscopal effect”) in people with multiple metastases. It may help by boosting the body’s response to stereotactic body radiotherapy (focused high-dose radiation) for tumors outside the brain.
SeoulAges 19 years+ - NCT07573111RecruitingPhase 1
QUAIL-100 for Children With Blood Cancers After Stem Cell Transplant
This study tests a new experimental treatment called QUAIL-100 in children and young adults who have had a stem cell transplant for a serious blood cancer. The treatment is designed to help the immune system fight remaining cancer cells.
Palo Alto, CaliforniaAges 1.5 years–39 years - NCT07572006RecruitingPhase 1
Study of JNJ-95804306 for blood cancers that returned or didn't respond
This trial tests a new drug called JNJ-95804306 for people with certain blood cancers (like acute myeloid leukemia, myelodysplastic syndromes, or chronic lymphocytic leukemia) that have come back or stopped responding to other treatments. The goal is to see if the drug is safe and if it can help.
Indianapolis, IndianaAges 18 years+ - NCT07569042RecruitingPhase 1/Phase 2
Continuing NBM-BMX and Temozolomide for Glioblastoma
This is a continuation study for patients who completed or are in the parent trial testing NBM-BMX (an experimental drug) combined with temozolomide (a standard brain-tumor chemotherapy) for newly diagnosed glioblastoma. If you tolerated the earlier treatment well and your doctor believes you could benefit, you may continue the same drugs in this rollover study.
Kaohsiung CityAges 18 years+ - NCT07573956RecruitingPhase 2/Phase 3
Fast versus standard radiation after head and neck cancer surgery
This trial compares two different radiation schedules after surgery for head and neck cancer. One schedule delivers radiation faster over fewer weeks, while the other uses the standard approach. The study tests whether the faster schedule works just as well while potentially reducing side effects.
Jhajjar, HaryanaAges 18–80 - NCT04278287RecruitingPhase 1/Phase 2
Chemoradiation study for unresectable esophageal cancer
This Phase 1/2 trial tests a treatment plan using chemotherapy plus radiation for esophageal squamous cell cancer that cannot be removed with surgery. It may help shrink or control the cancer and guide safer dosing, but it’s only for people with specific tumor stage, health status, and blood test results.
Anyang, HenanAges 18–75 - NCT07561437RecruitingEarly Phase 1
NK521 infusion for advanced cancer with fluid buildup
This early-stage trial tests NK521, a new immunotherapy infusion, for patients with advanced solid tumors (like liver, stomach, or colon cancer) that have spread and caused fluid buildup in the belly. The goal is to see if NK521 can help shrink tumors and improve survival when standard treatments have stopped working.
Beijing, Beijing MunicipalityAges 18–75
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Common questions
- Are there clinical trials for malignancy?
- Yes. Clin2 currently lists 1,543 recruiting malignancy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malignancy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malignancy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.