Clinical trials
Maternal Depression clinical trials
Below are recruiting maternal depression clinical trials, each written for real people, not researchers. We’re tracking 31 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06049433Recruiting
Mental health support for new and expecting mothers
This study tests a program to help pregnant women and new mothers who may be at risk for depression after childbirth. The program offers extra support and resources to improve your mental health and well-being.
Salt Lake City, UtahAges 18 years+ - NCT04069091Recruiting
Program to help mothers with depression during pregnancy or after birth
This trial studies a maternal depression prevention and early help program for people who screen positive for depression. It may help improve mental health during pregnancy or the postpartum period and support health for both parent and child.
Helsinki, UusimaaAges Any age - NCT06750796Recruiting
Half swaddling study for new mothers and babies
This study tests if half swaddling (wrapping your baby's lower body) helps improve your baby's sleep, your own sleep quality, and your mood. It is for healthy mothers with healthy full-term babies.
Edirne, None SelectedAges 18–45 - NCT06726304Enrolling by invitation
Increasing physical contact for mothers with anxiety or depression
This study tests whether using a baby carrier more often helps mothers with anxiety or depression feel more connected to their babies. It is for mothers who had a healthy baby and were diagnosed with anxiety or depression during pregnancy.
Montreal, QuebecAges 18 years+ - NCT05142384Recruiting
Online therapy program for mothers with depression symptoms
This study tests an internet-based cognitive behavioral therapy (an online skills-based talk therapy) to help mothers with depression symptoms. It’s offered through Head Start, where participating moms and their children connect with the program.
Springfield, OregonAges 2 years+ - NCT05400382Recruiting
Mindfulness for depression and pain after cesarean delivery
This study tests whether a mindfulness program can help new mothers manage pain and depression after a planned cesarean delivery. You might be eligible if you are a woman of color or non-Hispanic White with a history of depression and are scheduled for a planned C-section.
Champaign, IllinoisAges 18–45 - NCT06074250RecruitingPhase 2/Phase 3
Pregnancy, mood, and gut health study
This study tests whether a nutritional supplement can help prevent depression and anxiety during and after pregnancy. It looks at how the mother's gut bacteria may influence mood.
Toronto, OntarioAges 18–43 - NCT07272213Recruiting
Thyroid hormone levels, mood, and sexual health in pregnancy
This study looks at how thyroid-stimulating hormone (TSH) levels during pregnancy are linked to depression, anxiety, and sexual function in pregnant women.
Istanbul, GaziosmanpaşaAges 18–45 - NCT06623981Recruiting
Treating maternal depression in an urban asthma clinic
This study tests whether treating depression in Black mothers of children with asthma can improve both the mother's mood and the child's asthma. It offers support for mothers who are feeling down and may help their child's asthma get better.
Washington D.C., District of ColumbiaAges Any age - NCT06231602Recruiting
Depression and feeding in new mothers
This study looks at how a mother's mood after giving birth might affect how she feeds her baby. It aims to help first-time mothers get better support.
TaipeiAges 18 years+ - NCT07606248Recruiting
Virtual forest mindfulness for pregnant women's mental health
This study tests whether using virtual reality to explore a calming digital forest helps reduce stress and improve mood during pregnancy. You'd use a VR headset a few times to practice mindfulness (focused breathing and relaxation) and complete short surveys about how you're feeling.
HsinchuAges 18 years+ - NCT07083037Recruiting
Parent program to help kids' attention and behavior
This trial tests a program for mothers who have mild to moderate depression and whose child has attention or behavior problems. The program aims to improve both the mother's well-being and the child's behavior.
Winnipeg, ManitobaAges 18 years+ - NCT06545760Recruiting
Skin-to-skin care and mothers' mood after preterm birth
This study looks at whether giving kangaroo mother care (skin-to-skin contact) to a small or premature baby affects the mother's mood after childbirth. It may help understand how to support mothers' emotional well-being during their baby's hospital stay.
LusakaAges 1 day–89 years - NCT07354334Enrolling by invitation
Listening to a Quranic surah after cesarean birth
This study tests if listening to Surah Al-Inshirah after a cesarean helps new mothers feel better. It looks at things like pain, anxiety, and recovery.
Konya, SelçukluAges 18–45 - NCT04685148RecruitingPhase 1/Phase 2
Study of mental health treatment during pregnancy
This trial studies a treatment aimed at improving maternal mental health during pregnancy. It focuses on people who have had depression around pregnancy before, and checks whether the approach is safe and helpful for them.
CopenhagenAges 18–45 - NCT06544941Recruiting
Improving sleep and mental health in new moms
This study compares two types of bassinets to see if one helps mothers sleep better and feel less stressed after childbirth. It is for pregnant women with a military connection who are willing to use a bassinet and give a blood sample.
Colorado Springs, ColoradoAges 18–45 - NCT07214597Recruiting
Using voice technology to improve NICU mom experience
This trial tests a smartphone app called VoiceLove that lets moms record their voice for their baby in the NICU. It may help mothers feel more connected and supported while their baby is in the hospital.
Nashville, TennesseeAges 18 years+ - NCT07485036Recruiting
Study on mood and alcohol use in new mothers
This study looks at how new mothers feel emotionally, including mood, alcohol use, and symptoms of depression. By participating, you can help researchers understand the challenges mothers face in the first year after childbirth.
Chicago, IllinoisAges 18 years+ - NCT07613008Recruiting
Mobile app to prevent perinatal depression and anxiety
This study tests a personalized smartphone app designed to help pregnant women and their partners prevent depression and anxiety during pregnancy and after birth. Participants use the app for support and receive check-ins from healthcare providers.
Mairena del Aljarafe, SevillaAges 18 years+ - NCT07799805Recruiting
Doula support for pregnant women in North Central Florida
This study looks at whether having a doula—a trained support person—during pregnancy can help reduce stress and improve health outcomes for mothers. It is designed for women who are eligible for Medicaid and live in North Central Florida.
Gainesville, FloridaAges 15–49 - NCT06462638Recruiting
Contact and relationship in the NICU for preterm babies
This study looks at how contact and relationship-building between parents and their babies in the neonatal intensive care unit (NICU) can help. It is for babies born a bit early (33–36 weeks) who are now stable, and for their parents under 50.
MessinaAges 18–50 - NCT07292649Recruiting
Labor pain relief and postpartum depression risk
This study looks at how your expectations about pain relief during labor might affect your mood after giving birth. Researchers will follow you after delivery to see if there is a link between your hopes for pain management and the risk of postpartum depression.
Padova, VenetoAges 18 years+ - NCT07871916Recruiting
Mindfulness app for parents going through divorce or separation
This study tests a mindfulness app designed to help parents manage stress during divorce or separation. It may help you feel calmer and more focused as you navigate this challenging time.
Stamford, ConnecticutAges 18 years+ - NCT06442774Recruiting
Mamaconecta: app support for moms' mental health
This study tests a digital tool called MamaConecta to support mothers' mental health during pregnancy. If you are between 12 and 14 weeks pregnant, speak Spanish, and have a smartphone, you may be able to join.
Barcelona, CataloniaAges 18 years+
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Common questions
- Are there clinical trials for maternal depression?
- Yes. Clin2 currently lists 31 recruiting maternal depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a maternal depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a maternal depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.