Clinical trials
Mental Health Disorder clinical trials
Below are recruiting mental health disorder clinical trials, each written for real people, not researchers. We’re tracking 522 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06505590Recruiting
Online support for cancer-related fatigue
This trial tests an online support program designed to help people with cancer manage fatigue. If you have had moderate to severe fatigue for at least a week, you may be able to join from home.
VillejuifAges 18 years+ - NCT06512220RecruitingPhase 2
Psilocybin for treatment-resistant depression brain imaging study
This study tests whether a psilocybin-based treatment can help people with depression that has not improved after trying several antidepressants. You will receive the study treatment and have brain scans to see how it affects brain connections.
Toronto, OntarioAges 18–65 - NCT06544941Recruiting
Improving sleep and mental health in new moms
This study compares two types of bassinets to see if one helps mothers sleep better and feel less stressed after childbirth. It is for pregnant women with a military connection who are willing to use a bassinet and give a blood sample.
Colorado Springs, ColoradoAges 18–45 - NCT06553820Recruiting
Yoga for better sleep and blood pressure in older adults
This trial tests whether a gentle yoga program called MediYoga can help people aged 65 and older with high blood pressure improve their sleep quality, lower their blood pressure, and feel better overall. It is designed for people who can read and speak Danish and own a smartphone or tablet.
Herlev, CopenhagenAges 65 years+ - NCT06567210Recruiting
Insomnia treatment and emotional memory regulation for mental health
This study tests whether treating insomnia can help regulate emotional memories overnight, which may reduce the risk of developing or worsening mental health conditions. You may be eligible if you have both insomnia and some anxiety symptoms.
Macquarie Park, New South WalesAges 18–45 - NCT06582784Recruiting
Using a phone app to help cancer survivors with depression
This study tests a mobile app to help cancer survivors who are feeling depressed. If you have a smartphone and are willing to use an app for mood support, you may be able to join.
Charleston, South CarolinaAges 18 years+ - NCT06597474RecruitingPhase 2/Phase 3
Food-Body-Mind wellness program for preschoolers
This study tests a 16-week program called Food-Body-Mind that helps preschoolers and their families build healthy habits. It focuses on movement, eating well, and feeling good about your body, and is designed for children ages 3 to 5 in Head Start programs.
Jackson, MichiganAges 3–5 - NCT06651801Recruiting
Group therapy for anxiety or depression
This trial tests whether a virtual group therapy program is a good way to help people in Manitoba with anxiety or depression. If you're looking for support and can join a small online group, this might be a helpful option.
Winnipeg, ManitobaAges 18 years+ - NCT06682689Recruiting
Nerve stimulation study for new mothers' mental health
This study tests whether a gentle nerve stimulation device (tVNS) worn on the ear can help new mothers feel better emotionally after childbirth. It is for women whose babies had normal organ scans and who do not have certain medical conditions or current mood disorders.
Tübingen, Baden-WurttembergAges 18 years+ - NCT06702722Recruiting
Therapy and HIV support for moms in Malawi
This study tests if combining problem-solving therapy with HIV care support can improve mental health and HIV outcomes for pregnant women living with HIV in Malawi who have elevated depressive symptoms.
LilongweAges 18 years+ - NCT06389565Recruiting
Change My Story: A mental health program for young adults with HIV
This study tests a mental health program to help young people living with HIV who feel down or depressed. It's designed to see if talking through your story can help you feel better and function day-to-day.
Ibadan, Oyo StateAges 16–29 - NCT07625345RecruitingPhase 1
Brain Imaging Study of PDE4B Using a Radioactive Tracer
This research study uses a special radioactive tracer and imaging machines (PET and MRI scans) to take pictures of a specific protein in your brain called PDE4B. This is an early-stage study to see if this imaging method works safely and can help us understand brain chemistry in the future.
Bethesda, MarylandAges 18–101 - NCT06732128Recruiting
Nature virtual reality for depression in Alzheimer's disease
This trial tests whether a virtual reality nature experience can help improve mood in people with early-to-moderate Alzheimer's disease. Participants will use a VR headset and a few apps at home, with a caregiver present, over several sessions.
Toronto, OntarioAges 50 years+ - NCT06770075Recruiting
Brightline: testing a wellness app for college students
This study tests a smartphone app that may help students track and improve their mental well-being. Over 6 months, you will wear a device that monitors things like activity and sleep, and use a simple app to check in on your mood. It's designed for full-time undergraduates who do not have a current mental health condition and are not receiving mental health treatment.
SingaporeAges 18–25 - NCT06776523Recruiting
Psychological help study for refugees in Switzerland
This study tests a brief psychological program (Problem Management Plus, or PM+) to see if it helps refugees and asylum seekers feel better. If you are feeling stressed, anxious, or down, this may be an option for you.
ZurichAges 16 years+ - NCT06783283Recruiting
Brain stimulation to improve memory in mild cognitive impairment
This trial tests whether a gentle electrical brain stimulation technique called tACS can improve working memory in people with mild cognitive impairment (MCI). If you have MCI due to early Alzheimer's, this study may help find new ways to boost memory.
Toronto, OntarioAges 60 years+ - NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT06802939Recruiting
Personalized brain stimulation for voices in schizophrenia
This trial tests a targeted brain stimulation method (rTMS) using brain imaging to treat persistent auditory hallucinations that haven't improved with medication. It may help people with schizophrenia who continue to hear voices despite trying multiple antipsychotics.
ShanghaiAges 13–55 - NCT06809166RecruitingPhase 4
Contrave for weight loss in adults with obesity
This study tests whether a weight loss medication called Contrave can help adults with obesity lose weight by changing how their body uses energy and handles food. If you qualify, you will take Contrave and be monitored for several months.
Ottawa, OntarioAges 18–64 - NCT06845124RecruitingPhase 2
Testing CBD and naltrexone for alcohol craving
This trial is testing if taking cannabidiol (CBD) plus naltrexone can reduce alcohol craving in people with alcohol dependence. Naltrexone is already used to help with alcohol cravings, and CBD may add extra benefit.
Wiesloch, Baden-WurttembergAges 18–70 - NCT06871397Recruiting
Online support program for well-being in early pregnancy
This study tests an online program designed to help pregnant women feel better emotionally and mentally. It includes lessons and support you can access from your phone.
Reus, TarragonaAges 18 years+ - NCT06874205RecruitingPhase 1
Imaging a brain protein in healthy volunteers
This study tests a special imaging agent called 11C-JMJ-129 to see how it behaves in the brain and body of healthy volunteers. The goal is to better understand a brain protein called PDE4D, which may be linked to mood and anxiety disorders.
Bethesda, MarylandAges 18–101 - NCT06888726Recruiting
Brain stimulation for negative symptoms in schizophrenia
This trial tests if a gentle electric current applied to your head can help with negative symptoms (like lack of motivation or emotion). You must have schizophrenia, take a common antipsychotic, and have some ongoing negative symptoms.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06906185Recruiting
Trauma-informed support for pregnant veterans with anxiety or depression
This trial tests an online program designed to help pregnant veterans who have experienced trauma and are feeling anxious or depressed. The goal is to see if this program can improve their well-being during pregnancy.
New Orleans, LouisianaAges Any age
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Common questions
- Are there clinical trials for mental health disorder?
- Yes. Clin2 currently lists 522 recruiting mental health disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.