Clinical trials
Mental Health Impairment clinical trials
Below are recruiting mental health impairment clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06732128Recruiting
Nature virtual reality for depression in Alzheimer's disease
This trial tests whether a virtual reality nature experience can help improve mood in people with early-to-moderate Alzheimer's disease. Participants will use a VR headset and a few apps at home, with a caregiver present, over several sessions.
Toronto, OntarioAges 50 years+ - NCT07557017Recruiting
Emotional Disorder Treatment Study Using Unified Protocol
This study tests a structured therapy approach called the Unified Protocol, designed to treat multiple emotional disorders (like depression, anxiety, and OCD) with one flexible treatment. Researchers want to see if this approach helps people manage their symptoms over 14 weeks of outpatient therapy.
PragueAges 18 years+ - NCT07494110Recruiting
Aurora: AI storytelling for emotional wellbeing
This study tests a guided, AI-based storytelling tool to help people process their experiences and feel better emotionally. Depending on who you are, the session lasts 1 to 4 hours.
Barcelona, BarcelonaAges 18 years+ - NCT07483333Recruiting
Comparing two group therapies for kids with medical conditions and trauma
This study compares two types of group therapy for youth ages 8–18 who have a chronic medical condition and trauma-related distress. The goal is to see which type of group helps kids feel better and handle their health challenges.
Chicago, IllinoisAges 8–18 - NCT07475039Recruiting
Friendly phone calls to support older adults
This study tests whether a program of friendly phone calls from trained volunteers can help older adults feel more connected and supported. If you are 65 or older and already receive home-delivered meals or other services, you may be able to join.
Gainesville, FloridaAges 55 years+ - NCT07369752Recruiting
Breathing exercises for teens with depression or anxiety
This study looks at whether breathing exercises can help improve brain health and mental well-being in teens with depression or anxiety. It is designed for adolescents who are already receiving care at a Mayo Clinic psychiatry clinic.
Albert Lea, MinnesotaAges 12–17 - NCT07364799Recruiting
Sound therapy for stress in detained teens
This trial tests a multi-sensory therapy called SoundHeal for teens in juvenile detention. It uses sound and vibration to help with stress, anxiety, depression, or substance use.
San Luis Obispo, CaliforniaAges 12–18 - NCT07342907Recruiting
Internal Family Systems therapy for borderline personality disorder
This study tests a type of talk therapy called Internal Family Systems (IFS) to see if it helps people with borderline personality disorder (BPD). You would attend 50 therapy sessions over about 12-15 months to explore how this approach may improve your symptoms and well-being.
Tiny, OntarioAges 18 years+ - NCT07334561Recruiting
Brain stimulation for depression and pain
This study tests a non-invasive brain stimulation treatment (transcranial electrical stimulation) for people who have both depression and chronic pain. It aims to see if this treatment can help improve mood and reduce pain.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06508450Recruiting
Mental health support for minority young adults
This trial tests a program to help racial and ethnic minority young adults engage with mental health services. It aims to improve access and participation in care.
The Bronx, New YorkAges 18–34 - NCT07305688Recruiting
Climate anxiety and suicide risk in young people
This study explores how climate anxiety affects young people who are at risk for suicide. It aims to better understand the link between worries about climate change and suicidal thoughts or behaviors.
LimogesAges 16–24 - NCT07287878Recruiting
Brain stimulation to improve social reward in depression
This trial tests a new type of brain stimulation called temporal interference stimulation to see if it can improve how people with depression experience social rewards. You may be eligible if you have depression with certain features like increased appetite, weight gain, or feeling very sensitive to rejection, and you are between 16 and 60 years old.
Shanghai, ChinaAges 16–65 - NCT07281729Enrolling by invitation
Suicide risk factors study for mood disorders
This study looks at why some people with mood disorders (like depression or bipolar disorder) think about or attempt suicide. By finding the risk factors, doctors hope to better prevent suicide. The study involves filling out questionnaires.
Shanghai, Shanghai MunicipalityAges 16–60 - NCT07271485RecruitingEarly Phase 1
Propranolol for misophonia: a pilot study
This trial tests if a blood pressure medication called propranolol can reduce the intense anger or anxiety some people feel in response to everyday sounds (like chewing or breathing). If you have misophonia and meet the study’s health and safety criteria, you may be able to join and receive the medication under medical supervision at a clinic in Littleton, Colorado.
Littleton, ColoradoAges 18–65 - NCT07262580Enrolling by invitation
Finding meaning in cardiac rehab: a study
This study tests a program to help people in cardiac rehabilitation find personal meaning and purpose. It explores if the program works in individual, group, or paired sessions with a relative.
Odense, Region SyddanmarkAges 18 years+ - NCT07228182Recruiting
Brain stimulation study for gambling disorder
This trial tests a non-invasive brain stimulation method called high-intensity transcranial alternating current stimulation to see if it can reduce gambling urges and behavior in people with gambling disorder.
ShanghaiAges 18–60 - NCT07225088Recruiting
Mental health support for Latino cancer patients
This study tests a mental health intervention called DESCANSO to help Latino people with cancer who feel depressed, have trouble sleeping, or are very tired. You may join if you are a Latino adult with stage I-III solid tumor cancer, speak Spanish, and are currently or recently finished treatment.
Basking Ridge, New JerseyAges 21–100 - NCT07223346Recruiting
Fitness and therapy for Latina cancer survivors
This trial offers a program combining exercise and mental health support for Latina women in Colorado who have recently finished cancer treatment or are still undergoing it. It aims to improve well-being through group sessions focused on physical activity and coping skills.
Fort Collins, ColoradoAges 18 years+ - NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT07209306Recruiting
Psychological help for migrants in Italy: The ADVANCE trial
This trial tests two WHO-designed psychological programs (called SH+ and DWM) to help migrants in Italy cope with stress, anxiety, and depression. You will be randomly assigned to one of the programs to see if they improve your mental health and well-being.
Verona, ItalyAges 18 years+ - NCT07211438RecruitingPhase 2
Psilocybin with Monitors for Treatment-Resistant Depression
This study tests whether trained monitors improve the safety and outcomes of psilocybin therapy for people with depression that hasn't responded to other treatments. Participants will receive psilocybin in a supervised setting and will need to temporarily stop other psychiatric medications.
Toronto, OntarioAges 18–70 - NCT06493825Recruiting
Mindfulness app for kids with severe tinnitus or misophonia
This trial tests whether a virtual reality mindfulness app can help children aged 10–18 with severe tinnitus or misophonia feel better mentally. It compares the mindfulness app to a placebo (sham) version.
Aurora, ColoradoAges 10–18 - NCT06934954Recruiting
Emotion Skills Program for Early Teens
This program teaches young teens (ages 10-15) and their parents simple skills to handle difficult emotions. It is not for children who are in immediate danger or have severe learning problems.
New York, New YorkAges 10 years+ - NCT07198594Recruiting
Fast brain stimulation for hard-to-treat OCD
This study tests a fast-acting brain stimulation method (accelerated rTMS) for people whose obsessive-compulsive disorder has not improved enough with standard treatments. It aims to help those who still have moderate to severe symptoms despite trying multiple medications.
Shanghai, Shanghai MunicipalityAges 18–60
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Common questions
- Are there clinical trials for mental health impairment?
- Yes. Clin2 currently lists 181 recruiting mental health impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.