Clinical trials
Mental Health Impairment clinical trials
Below are recruiting mental health impairment clinical trials, each written for real people, not researchers. We’re tracking 181 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06401239Recruiting
Study on recovery from severe breathing problems
This study looks at how recovery goes for people who had severe breathing problems in the hospital. It involves talking with you and a partner who helps care for you, to learn how to improve support for both of you.
Baltimore, MarylandAges 18 years+ - NCT07667686Recruiting
French version of recovery survey for psychiatric patients
This study tests a French version of a questionnaire called the Recovery Assessment Scale. It asks about your personal experience of recovery while receiving psychiatric care. Your answers may help improve mental health services.
Jury, MoselleAges 18 years+ - NCT04396873RecruitingPhase 1
PET brain scan study of inflammation markers in neurodegeneration
This Phase 1 study tests a PET scan to measure inflammation-related changes in the brain using a medication called ketoprofen. It may help researchers understand which people with certain brain diseases could benefit from treatments aimed at inflammation.
Bethesda, MarylandAges 18–99 - NCT04668560Recruiting
Testing a “5 Ways to Wellbeing” course for health support
This trial studies whether a structured “5 Ways to Wellbeing” course can help people make healthier choices and cope better with health problems or long-term (chronic) illness. It may be especially relevant if you’re currently off work due to health concerns or receiving support payments.
OsloAges 18 years+ - NCT07559266Recruiting
HIV Treatment and Well-Being Program for Young Gay Men
This study helps young gay and bisexual men with HIV in Vietnam improve their treatment outcomes and overall well-being. Researchers will work with you at your clinic to provide support and monitor your health while you're taking HIV medications.
Ho Chi Minh CityAges 18–24 - NCT06117163Recruiting
Mental health care for pregnant women with HIV in Kenya
This study tests a program that provides integrated mental health care for pregnant women living with HIV in Kenya. The goal is to improve both mental health and HIV treatment outcomes during pregnancy.
NairobiAges 15 years+ - NCT06780917Recruiting
Online cognitive testing for older adults with depression or memory concerns
This study tests whether an online cognitive assessment platform (Creyos) is valid for older adults with major depression or mild cognitive impairment. Participants will complete brain games or puzzles to see how well the online tool measures thinking skills.
Toronto, OntarioAges 60 years+ - NCT06511908RecruitingPhase 2
Testing a new ketamine-like drug for hard-to-treat depression
This study tests a new experimental drug (2R,6R)-HNK, a chemical related to ketamine, given by IV infusion to see if it can help people with depression that hasn't improved with other treatments. The goal is to find a new option for people who have not found relief from standard antidepressants.
Bethesda, MarylandAges 18–70 - NCT07404085Recruiting
Boosting thinking skills with training and medication in mood or schizophrenia disorders
This study tests whether adding a medication that may improve brain flexibility makes memory and thinking training work better for people with bipolar disorder, recurring depression, or schizophrenia spectrum disorders. It could help improve daily thinking skills and quality of life.
Frederiksberg, Capital Region of DenmarkAges 35–75 - NCT07877246Recruiting
Immune markers in brain-related illness
This study looks at blood and other samples from people with brain-related conditions that might involve inflammation or infection. It aims to find immune markers that could help understand these illnesses better.
Los Angeles, CaliforniaAges 1 month–100 years - NCT07227545Recruiting
Brain stimulation study for alcohol use disorder
This study tests a non-invasive brain stimulation treatment (using a mild electrical current) to see if it can help people reduce their alcohol use. It aims to improve symptoms of alcohol use disorder, which may help with recovery.
ShanghaiAges 18–60 - NCT07640802Recruiting
Comparing talk therapies for irritability in children
This study compares two types of talk therapy for children who have frequent, intense irritability or temper outbursts. The goal is to see if a specific new therapy works better than a supportive, educational approach that does not include the active treatment techniques.
Bethesda, MarylandAges 8–17 - NCT05583747Recruiting
Brain stimulation therapy with guidance for treatment-resistant depression
This study tests a type of brain stimulation (guided iTBS) to improve depression when standard antidepressant treatments haven’t helped. It also checks that the treatment is safe for people who can meet the study and scan safety requirements.
Toronto, OntarioAges 18–65 - NCT06417437RecruitingPhase 4
Brain-computer interface test for depression
This trial tests a non-invasive brain-computer interface (BCI) to help people with depression. It may be a good fit for teenagers and adults who are right-handed, Han Chinese, and have moderate to severe depression without other major health problems.
Shanghai, Shanghai MunicipalityAges 12 years+ - NCT07717723Recruiting
Support for caregivers of heart disease patients
This study tests a program to help caregivers of people with heart disease manage stress and challenges. It aims to support your mental health while caring for a loved one.
Sacramento, CaliforniaAges 18 years+ - NCT07682064Recruiting
Group therapy for emotional disorders in adults
This trial tests a group therapy program for adults with emotional disorders like depression or anxiety. It is designed to help you manage difficult emotions and improve your well-being.
Logroño, La RiojaAges 18–65 - NCT07673380RecruitingPhase 2
Mobile health for opioid recovery and mental health
This study uses a mobile health app to help Black and African American individuals recover from opioid or stimulant use and improve mental health. It aims to see if the app can support treatment and well-being.
St Louis, MissouriAges 18 years+ - NCT07658898Recruiting
Brain stimulation for negative and cognitive symptoms in schizophrenia
This study tests a new type of brain stimulation called temporal interference to see if it can help with negative symptoms (like lack of motivation or emotion) and cognitive symptoms (like trouble with memory or focus) in schizophrenia. It uses a special head device to target a specific brain area.
ShanghaiAges 18–65 - NCT07649733Recruiting
Virtual Reality Wellness Program for Healthcare Workers
This study tests whether using virtual reality can help healthcare workers reduce stress and improve well-being. You would attend weekly sessions using a VR headset designed to help you relax.
Badalona, BarcelonaAges 18 years+ - NCT07637747Recruiting
Mental Health Decision Aids: Impact and Patient Experience
This study looks at how decision aids—tools that help you understand your treatment options—work in mental health care. Researchers want to learn if these tools help patients like you make better choices about your care.
OdenseAges 18 years+ - NCT07627386Recruiting
Lifestyle Program for Older Spouses Caring for Partners
This study tests whether a lifestyle intervention program can help older adults who are caregivers for spouses with memory problems. The program focuses on improving diet, exercise, cognitive activity, and social engagement to support both the caregiver's health and their ability to provide care.
KuopioAges 65 years+ - NCT07615257Recruiting
Mindfulness and CBT for Psoriasis-Related Emotional Stress
This study tests whether a combination of mindfulness and cognitive behavioral therapy (CBT)—talk-based techniques to manage thoughts and emotions—can help psoriasis patients feel less stressed and more compassionate toward themselves. Participants attend sessions over several weeks to learn these skills.
Rahim Yar Khan, Punjab ProvinceAges 25–75 - NCT07610928Recruiting
Stress management and gentle movement for Asian Americans with depression
This study tests whether learning stress management and gentle movement (like Tai Chi or Qigong) can help Asian Americans with depression and physical symptoms. It may offer a way to feel better that you can do from home in online group sessions.
Boston, MassachusettsAges 18 years+ - NCT07566468Recruiting
Brain rhythm study for youth with ADHD or OCD
This study uses MRI and EEG to understand brain activity related to attention and impulse control in teens with ADHD or OCD. It may help researchers develop better treatments.
Bethesda, MarylandAges 10–17
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Common questions
- Are there clinical trials for mental health impairment?
- Yes. Clin2 currently lists 181 recruiting mental health impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.