Clinical trials
Mental Health clinical trials
Below are recruiting mental health clinical trials, each written for real people, not researchers. We’re tracking 727 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07305701Recruiting
Study on Medical Students' Mental Health
This study follows first-year health students at the University of Orléans to understand their mental health over time. It aims to find ways to support students' well-being during their studies.
Orléans, LoiretAges 18 years+ - NCT07321964Recruiting
Digital yoga for quality of life with atrial fibrillation
This trial tests if a digital yoga program can improve quality of life, blood pressure, and heart rate in people with atrial fibrillation. It offers a convenient way to practice yoga from home using a smartphone or tablet.
HerlevAges Any age - NCT07342907Recruiting
Internal Family Systems therapy for borderline personality disorder
This study tests a type of talk therapy called Internal Family Systems (IFS) to see if it helps people with borderline personality disorder (BPD). You would attend 50 therapy sessions over about 12-15 months to explore how this approach may improve your symptoms and well-being.
Tiny, OntarioAges 18 years+ - NCT04916327Recruiting
Exercise program study for mental health and blood vessel health
This study tests whether an exercise training program can improve how well your blood vessels work in people with certain mental health conditions. You may join as someone with PTSD, someone with generalized anxiety, or as a healthy control group.
Richmond, VirginiaAges 18–35 - NCT07679204Recruiting
Personality and life satisfaction in bipolar and depression
This study looks at how personality traits and life satisfaction affect people with bipolar II disorder or major depression. You will fill out questionnaires about your feelings and daily life.
ElâzığAges 18 years+ - NCT07364799Recruiting
Sound therapy for stress in detained teens
This trial tests a multi-sensory therapy called SoundHeal for teens in juvenile detention. It uses sound and vibration to help with stress, anxiety, depression, or substance use.
San Luis Obispo, CaliforniaAges 12–18 - NCT07369752Recruiting
Breathing exercises for teens with depression or anxiety
This study looks at whether breathing exercises can help improve brain health and mental well-being in teens with depression or anxiety. It is designed for adolescents who are already receiving care at a Mayo Clinic psychiatry clinic.
Albert Lea, MinnesotaAges 12–17 - NCT07386574Recruiting
Digital training for health workers on substance use
This trial tests a digital training program for frontline health workers to help them better recognize and support people with substance use disorders. It aims to make it easier for patients to get the right care from providers they already see.
KarachiAges 18 years+ - NCT00001360Recruiting
Brain Blood Flow During Thinking Study
This research study uses brain imaging to see how blood flows in your brain while you think and perform tasks. Researchers hope to better understand how healthy brains work during different types of thinking.
Bethesda, MarylandAges 18–65 - NCT01266577Recruiting
MRI study measuring brain and muscle chemical levels
This study uses MRI techniques to measure natural chemical “metabolites” in the brain and muscle. You may be able to join if you’re generally healthy and can safely complete a long MRI scan.
Bethesda, MarylandAges 18–65 - NCT01087281Recruiting
Testing how brain “top-down” attention helps visual processing
This study looks at how signals from the brain’s thinking/attention systems affect how we process what we see. It may help researchers understand brain attention after stroke or other focal brain injuries, and compare with healthy volunteers.
Bethesda, MarylandAges 18–100 - NCT00024635Recruiting
Understanding Mood and Anxiety Disorders Study
This research study evaluates people with mood disorders (like depression or bipolar disorder), anxiety disorders, or people without these conditions to better understand how these conditions develop and affect the brain. Researchers will ask questions and may do other assessments to learn more.
Bethesda, MarylandAges 3–99 - NCT00025935Recruiting
Brain Function Studies in Youth With Mood and Attention Disorders
This research study examines how the brains of children and teenagers with mood problems (like persistent irritability or depression) or attention difficulties work differently. Researchers use brain scans and tasks to understand these conditions better and track changes as young people grow up.
Bethesda, MarylandAges 7–60 - NCT00109174Recruiting
Brain scan study measuring glutamate and GABA
This study uses MRI to measure certain chemicals in the brain (glutamate and GABA) and see how they are metabolized. You may be able to join if you are healthy, can safely have an MRI, and meet the specific enrollment requirements.
Bethesda, MarylandAges 18–65 - NCT01327690RecruitingEarly Phase 1
Group therapy for mental health in veterans and families
This early-stage study looks at mental health outcomes for active-duty service members, veterans, and their family members after participating in group therapy sessions. If you can follow instructions and complete consent forms, this trial may help researchers understand how group therapy affects well-being in these communities.
Santa Rosa, CaliforniaAges 18–80 - NCT00397111Recruiting
MRI brain-scanning study of mood and anxiety in adults
This study uses brain MRI scans and mental tasks to better understand mood and anxiety problems. It may help researchers develop improved MRI methods for studying depression and healthy brain function.
Bethesda, MarylandAges 18–65 - NCT01132885Recruiting
Brain scans in children with Williams syndrome
This study uses brain testing—often MRI scans—to learn how the brains of children with Williams syndrome are different from typical development. It may help researchers better describe brain patterns and improve future care for people with Williams syndrome.
Bethesda, MarylandAges 5 years+ - NCT02640911Recruiting
Long-term study of certain antipsychines in schizophrenia
This is an observational (non-intervention) study that follows adults with schizophrenia who are taking specific “atypical” antipsychotic medicines long-term. Researchers want to learn about patients’ experiences and outcomes while on these treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT02543983RecruitingPhase 2
Brain scan and ketamine study for suicidal thoughts
This trial studies how ketamine affects the brain in people dealing with suicidal thoughts or an active suicide crisis. It uses questionnaires, consent testing, and brain imaging to look for biological changes that may relate to symptom improvement.
Bethesda, MarylandAges 18–70 - NCT03065335RecruitingPhase 1
Ketamine plus brain imaging to study response in depression
This early-stage study tests how ketamine given once and then repeatedly may change brain signals and related biomarkers in people with major depression. If you’re eligible, the team will use brain imaging and assessments to see who responds and why.
Bethesda, MarylandAges 18–65 - NCT07675538Enrolling by invitation
High intensity training for adults with ADHD
This trial tests whether high intensity exercise helps adults with ADHD. You'll participate in a supervised training program to see if it improves your symptoms.
BergenAges 18 years+ - NCT07404085Recruiting
Cognitive training with medication for mood disorders
This trial tests if a medication can boost the effects of cognitive training in people with bipolar disorder or recurrent depression who have memory or thinking problems. It aims to improve daily functioning.
Frederiksberg, Capital Region of DenmarkAges 40–75 - NCT07417813Recruiting
Lemborexant for insomnia in people with mental health conditions
This study tests if lemborexant, a sleep medication, can help people with both a mental health condition and insomnia. You would take the medicine as prescribed and complete questionnaires over 2 months.
Suzhou, JiangsuAges 18 years+ - NCT07420426Recruiting
Smartphone therapy for memory and mood problems
This trial tests a therapy program delivered by text or voice message on your smartphone. It's designed to help people with mild memory problems manage mood or behavior changes.
Hong KongAges 50 years+
Hear when a new Mental Health trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for mental health?
- Yes. Clin2 currently lists 727 recruiting mental health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.