Clinical trials
Metabolic Disease clinical trials
Below are recruiting metabolic disease clinical trials, each written for real people, not researchers. We’re tracking 366 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06660524RecruitingPhase 4
Calcium-phosphorus therapy for heart valve disease
This trial tests a treatment to lower high calcium and phosphorus levels in your blood, which may slow down calcium buildup in heart valves. It may help people with kidney problems who have valve disease.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07083336Recruiting
Diet study for type 2 diabetes with fatty liver disease
This trial tests a specific medical nutrition therapy diet to see if it can reduce liver fat and improve blood sugar control in people with type 2 diabetes and nonalcoholic fatty liver disease. It may help you manage both conditions with a dietary approach.
Yichang, HubeiAges 18 years+ - NCT06559878Enrolling by invitation
Liver Mitochondria Study in Fatty Liver Disease
This study looks at how the liver's mitochondria (the energy powerhouses of cells) work in people with fatty liver disease. Participants will have an MRI scan and receive a small amount of fat solution through an IV to see how the liver processes fat.
Helsinki, UusimaaAges 18–75 - NCT02830308Recruiting
Adult study evaluating endocrine and metabolic health
This trial enrolls adults with known or suspected hormone (endocrine) or metabolism-related conditions for clinical evaluation. The goal is to help doctors assess and better understand what’s causing these health problems.
Bethesda, MarylandAges 18–100 - NCT06852612Recruiting
Dietary strategies for glycogen storage disease type I
This trial tests different diet strategies to help adults with GSDI (a metabolic condition also known as von Gierke disease) maintain stable blood sugars and avoid dangerous drops. It may help you learn how to better manage your condition through diet.
BernAges 18 years+ - NCT06511297Recruiting
How aging and weight affect health: a deep-dive study
This study looks at how aging and body weight affect health and metabolism. Researchers will collect detailed measurements (like scans and blood tests) to understand why some people age better than others. You may join if you are in one of five age/weight groups.
Vienna, State of ViennaAges 18 years+ - NCT07564947Enrolling by invitation
Reishi Mushroom for Fatty Liver Disease
This study tests whether Ganoderma lucidum (reishi mushroom) can improve liver health and reduce inflammation in people with fatty liver disease. Researchers will measure how it affects your liver function and antioxidant levels.
Peshawar, Khyber PakhtunkhwaAges 35–49 - NCT04284943Recruiting
Surgery for stomach cancer and diabetes
This trial tests a surgery for early-stage stomach cancer that also aims to improve type 2 diabetes by changing how your body processes food. It might be an option if you have both conditions and are not using insulin.
SeoulAges 20–69 - NCT07185932RecruitingEarly Phase 1
Rifaximin for fatty liver with metabolic issues
This trial tests if rifaximin, a gut-targeted antibiotic, can help people with fatty liver disease who also have metabolic problems like obesity or diabetes. You need a recent fatty liver diagnosis and a liver fat level of at least 8% on an MRI scan.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05597709Recruiting
Study diabetes patients to measure MAFLD in Jiangsu
This study checks how common a condition called MAFLD is among people with type 2 diabetes in Jiangsu, China. It may help doctors understand how often this liver-related problem occurs and guide future care for people with type 2 diabetes.
Nanjing, JiangsuAges 18 years+ - NCT07246421Recruiting
Glucagon resistance in fatty liver and diabetes
This study looks at how people with fatty liver and type 2 diabetes respond to glucagon, a hormone that helps control blood sugar. It may help researchers understand a condition called 'glucagon resistance' and find better treatments.
AarhusAges 30–70 - NCT07646197Recruiting
Peanut Consumption and Fatty Liver Disease in Adults
This study tests whether eating peanuts regularly can help improve fatty liver disease (a condition where fat builds up in the liver). You'll be asked to eat peanuts as part of your diet while researchers track changes in your liver health.
Detroit, MichiganAges 30–70 - NCT06900244Enrolling by invitation
Metabolic Imaging for MS and Stroke
This study uses a special type of MRI scan to look at how energy is used in the brain. It may help researchers better understand neurological diseases like multiple sclerosis (MS) and stroke.
OxfordAges Up to 99 years - NCT04740580RecruitingEarly Phase 1
Test glutathione for brain inflammation in Alzheimer’s
This early-stage study tests whether taking glutathione can affect brain “inflammation” and metabolism in people with Alzheimer’s disease. You might benefit from a new treatment approach, while helping researchers understand what works best for early Alzheimer’s-related brain changes.
Houston, TexasAges 55–85 - NCT05332613Recruiting
Diet and meal timing study for fatty liver
This study looks at whether changing when and how people eat can improve fatty liver disease caused by metabolic problems. It uses MRI to measure liver fat and compares outcomes while participants follow a structured eating schedule.
New York, New YorkAges 18–65 - NCT07682363Recruiting
Survey on MASLD management by Chinese doctors
This study surveys doctors in China about how they manage Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD), a type of fatty liver disease. It aims to understand current practices and improve patient care.
BeijingAges 18 years+ - NCT07097506RecruitingPhase 2
Ketone drink for liver fat and health
This study tests whether a daily ketone ester drink can reduce liver fat and improve metabolism in people with excess liver fat. You may join if you are 18–40, have overweight or obesity, and your liver has extra fat.
St Louis, MissouriAges 18–40 - NCT07459504RecruitingPhase 2
Smart diets for kids with fatty liver disease
This study compares different diet plans to see which works best to reduce fat in the liver of children and teens with MASLD (a type of fatty liver disease). If your child drinks sugary beverages often and has certain health risks like being overweight or having high cholesterol, this trial may help find a healthy eating plan that works.
Grand Rapids, MichiganAges 11–17 - NCT06968234Recruiting
Liver disease breath test study
This study uses a special breath test to learn about chronic liver disease. If you have liver disease or cirrhosis, you may be able to help by providing a breath sample.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT03128996RecruitingPhase 1/Phase 2
Bone marrow transplant with lighter chemo for non-cancer illnesses
This early-phase study tests a safer “lighter” conditioning chemo plan before a bone marrow transplant for people with non-cancer blood and immune disorders. It aims to reduce transplant risk while using donor marrow that does not match perfectly in the HLA type.
New Haven, ConnecticutAges 1 day–21 years - NCT04157179Recruiting
MRI study of brain oxygen use in children and adults
This study uses an MRI scan to measure how your brain uses oxygen. It includes healthy participants and people with sickle cell disease or who previously needed ECMO, which may help researchers understand brain oxygen problems and how to monitor them.
St Louis, MissouriAges 3–50 - NCT05305287RecruitingPhase 4
Study how energy use in the liver works in people with fatty liver and diabetes
This trial measures how your liver cells use energy (mitochondrial function) in people with type 2 diabetes and fatty liver. It aims to better understand what is happening in the liver and how disease severity may relate to diabetes.
San Antonio, TexasAges 18–80 - NCT05632562RecruitingEarly Phase 1
PET/MRI scan study for newly diagnosed brain cancer changes
This early-phase study uses special PET/MRI scans to look at how a newly diagnosed high-grade glioma is changing under standard treatment. The goal is to see whether these scans can better assess the disease, which may help guide future care.
Birmingham, AlabamaAges 10–89 - NCT06490432Recruiting
Heart Rhythm Study in Fatty Liver Patients
This study is looking at whether people with a common fatty liver condition (MASLD) have abnormal heart rhythms. If you have MASLD and are 18 or older, you may join to help doctors see if your liver affects your heart's electrical activity.
Sohag, SoAges 18 years+
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Common questions
- Are there clinical trials for metabolic disease?
- Yes. Clin2 currently lists 366 recruiting metabolic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.