Clinical trials
Metabolic Disease clinical trials
Below are recruiting metabolic disease clinical trials, each written for real people, not researchers. We’re tracking 366 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06932042Recruiting
Protein-controlled diet for kidney disease management
This trial tests a low-protein diet (called PLADO) to help manage chronic kidney disease (CKD) stages 3–5. It aims to slow kidney decline and improve nutrition. You may join if your kidney function is stable and your blood sugar and blood pressure are under control.
BeirutAges 18 years+ - NCT07048158Recruiting
A drink for heart health
This study tests a drink called 'Perfect Heartio' to see if it supports cardiovascular health in healthy adults. It may help improve heart function or reduce risk factors.
Cheras, Kuala LumpurAges 18 years+ - NCT07111208Recruiting
Air, noise, and lifestyle effects on heart health
This study tests if wearing a wristband that tracks air and noise can help reduce heart risks in people with early signs of metabolic syndrome. You will also get lifestyle tips to help protect your heart.
Kaunas, Kaunas CountyAges 45–64 - NCT07410637Recruiting
Thyroid hormones and energy in graves' or thyroid cancer
This trial studies how thyroid hormone levels affect your body's use of sugar and energy. It may help people newly diagnosed with Graves' disease or thyroid cancer understand their metabolism better.
Ulm, Baden-WurttembergAges Any age - NCT07603817Recruiting
Thyroid Disease and Fatty Liver Disease Study
This study looks at the connection between thyroid problems (especially when the thyroid doesn't make enough hormone) and a common liver condition where fat builds up in the liver. Researchers want to understand how these two conditions relate to each other in people without diabetes.
Sohag, Sohag GovernorateAges 18 years+ - NCT05216042Recruiting
Study of genetics and heart/metabolic health in adults
This study looks at how genetic markers (DNA) relate to heart health and “metabolic” health (how your body manages sugar and fat). You may be asked to provide genetic samples and follow study health checks and protocols to help researchers understand who is at higher risk.
Birmingham, AlabamaAges 18 years+ - NCT05330923Recruiting
HIV and fatty liver check-in study with ultrasound follow-up
This study follows people with HIV who also have fatty liver disease and checks their health over time. It may help by improving monitoring and care planning, especially using ultrasound scans and regular follow-up.
Beijing, Beijing MunicipalityAges Any age - NCT07518784Recruiting
Testing a new liver scanning device for fatty liver disease
This study tests a new device called LiverScope® that scans your liver to detect fatty liver disease (MASLD). The scan uses special imaging technology and may help doctors diagnose liver disease more quickly and accurately.
La Jolla, CaliforniaAges 18 years+ - NCT04654000Recruiting
Rheopheresis to treat painful skin damage in calciphylaxis
This trial studies whether a treatment called rheopheresis, added to standard care, can help people with calciphylaxis whose skin wounds are getting worse. It may be considered when ulcers or dead (necrotic) skin appear despite conventional treatment.
AngersAges 18 years+ - NCT07136844Recruiting
Walking and arm movement study for nerve and muscle conditions
This study uses motion analysis to understand walking and arm function in adults with certain neurological or metabolic diseases. The goal is to find patterns that help doctors better manage these conditions.
LiègeAges 18 years+ - NCT06545565RecruitingPhase 3
Preventing acid buildup in preterm babies on IV nutrition
This trial tests if replacing sodium chloride with sodium acetate in IV nutrition can prevent metabolic acidosis (too much acid in the blood) in preterm babies born before 33 weeks. If your baby is in the NICU and needs IV nutrition, this study may help keep their blood chemistry balanced.
Karachi, SindhAges 1 day–3 days - NCT07565727Recruiting
Heart Health and Metabolism in Early Pregnancy
This study looks at how the body processes sugar and nutrients during pregnancy in women at higher risk for pre-eclampsia (a serious pregnancy condition with high blood pressure). Researchers want to understand if taking low-dose aspirin helps protect heart and metabolic health. You'll have blood tests, body composition scans, and metabolic measurements.
Knoxville, TennesseeAges 18–45 - NCT05223530Recruiting
Study of how pregnancy programs future child health
This study follows mothers who previously joined two specific pregnancy research programs, to understand why some children may be more likely to develop weight and heart-related health problems later. If you were part of those original studies, your information could help researchers look for early predictors and prevention ideas.
HelsinkiAges 11–55 - NCT05242315RecruitingPhase 4
Long-acting tacrolimus after liver transplant
This trial studies whether taking an extended-release form of tacrolimus (a medicine to prevent transplant rejection) after a liver transplant works well for people who are followed at the University of Alberta. It may help simplify dosing and monitor safety and effectiveness after transplant.
Edmonton, AlbertaAges 18 years+ - NCT05443100Recruiting
Testing whole-body cold therapy for metabolic, neurologic, or fibromyalgia pain
This trial studies whether a whole-body cold therapy called “WBC” can help people with certain metabolic conditions, neurologic conditions, or fibromyalgia. You may be able to join if you meet age and weight requirements and don’t have certain medical or safety risks.
Oggebbio, Verbano-Cusio-OssolaAges 18–65 - NCT06216678Recruiting
Can healthy diets with plant oils improve heart health?
This study tests if adding plant oils to a healthy diet can improve cholesterol and other heart health markers in people with moderately high cholesterol. It involves following a specific meal plan and having your health monitored over several weeks.
University Park, PennsylvaniaAges 25–60 - NCT06403189Recruiting
Studying choroid plexus function in brain diseases
This study looks at how a part of the brain called the choroid plexus works in people with different brain conditions. It may help find better ways to diagnose or treat these diseases.
ParisAges 18 years+ - NCT06481020Recruiting
Plant sterols for heart health in overweight adults
This study tests whether plant sterols (natural compounds found in plants) can help improve cholesterol and other heart health markers. If you are overweight and have high LDL cholesterol, you may be able to join this study to see if adding plant sterols to your diet helps.
ValenciaAges 18–80 - NCT06634160Recruiting
Fatty liver disease in people with high cholesterol
This study checks how common fatty liver disease is in people with a genetic form of high cholesterol. It may help researchers understand the link between these two conditions.
AngersAges 35 years+ - NCT06694012Recruiting
Ohtori Study Part 2 heart health
This study looks at heart and metabolic health in the general population. It helps researchers understand how to prevent conditions like diabetes and heart disease.
Sakai, OsakaAges 20 years+ - NCT07255300Recruiting
Fasting-mimicking diet for aging and health in adults
This study tests whether a special low-calorie diet that mimics fasting can help reduce risk factors for aging and age-related diseases. It is for healthy adults aged 30 to 65 who are willing to follow this diet for several days each month.
Varapodio, Calabria, ItalyAges Any age - NCT07452614Recruiting
Predicting pulp treatment success with metabolic markers
This trial tests if a metabolic biomarker can predict how well a vital pulp treatment works for tooth pain caused by deep cavities. It aims to help patients keep their natural teeth instead of needing root canals.
BaghdadAges 16–50 - NCT07652892Recruiting
Fatty Liver, Memory, and Health in Men and Women
This study looks at how fatty liver disease (related to metabolism) affects memory, strength, and quality of life—especially comparing men and women. It helps understand why some people with fatty liver feel more tired or have trouble thinking clearly.
Barcelona, BarcelonaAges 20–80 - NCT04720560Recruiting
Study how immune cells affect fatty liver disease
This study looks at how certain immune cells (“regulatory B cells”) may contribute to metabolic fatty liver disease. You might be able to join if you’re an adult with fatty liver but not pregnant and not on certain treatments.
AsyutAges 18–80
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Common questions
- Are there clinical trials for metabolic disease?
- Yes. Clin2 currently lists 366 recruiting metabolic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.