Clinical trials
Metabolic Disease clinical trials
Below are recruiting metabolic disease clinical trials, each written for real people, not researchers. We’re tracking 364 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06072963RecruitingPhase 2
Combining insulin and semaglutide for memory in MCI with metabolic syndrome
This study tests if a combination of insulin and semaglutide (a diabetes drug) can improve memory and thinking in people with mild cognitive impairment (MCI) who also have metabolic syndrome (a cluster of health issues like large waist, high blood sugar, and high blood pressure). It aims to see if treating blood sugar problems helps protect the brain.
Ramat GanAges 60–90 - NCT07481734RecruitingPhase 2
Tesamorelin for reducing liver fat in fatty liver disease
This trial tests if tesamorelin, a daily injection, can reduce liver fat in adults with fatty liver disease. It may help people whose liver has fat but is not yet scarred into cirrhosis.
Shenzhen, GuangdongAges 18–75 - NCT03131427Recruiting
Registry for inherited liver and metabolism-related conditions
This is a study that collects health information and samples (if applicable) from people with certain genetic or metabolic liver diseases. It may help doctors better understand these conditions and improve future care.
Beijing, Beijing MunicipalityAges Any age - NCT06528639Recruiting
Exercise program to reduce heart and metabolic risk
This study tests whether a personalized exercise plan guided by a special breathing test can help lower your risk for heart disease and related conditions. You may qualify if you are not very active and have early signs of metabolic syndrome like a larger waist, higher blood sugar, or higher blood pressure.
Beijing, Beijing MunicipalityAges 30–65 - NCT06868992Recruiting
Study of MASH and cell changes in weight-loss surgery
This study looks at a possible link between MASH (liver inflammation with fat buildup) and tiny cell structures that help liver cells work. Researchers want to understand this better in people having weight-loss surgery, where a small liver sample will be taken.
Lyon, FranceAges 18–99 - NCT07280143Recruiting
MASLD risk in breast or colorectal cancer survivors
This study looks at whether breast or colorectal cancer survivors are more likely to develop a liver condition called MASLD (fatty liver disease not caused by alcohol). It uses blood tests, imaging, and possibly an MRI to check liver health.
BernAges 18 years+ - NCT07313007Recruiting
Gut bacteria chemicals in fatty liver disease
This study looks at whether the natural chemicals made by your gut bacteria from the food you eat could affect liver fat and health. If you have MASLD (a fatty liver condition), researchers want to measure these gut-produced substances to better understand the disease.
Pierre-BéniteAges 18–80 - NCT06051318Recruiting
Diet and gut microbiome effects on blood sugar in healthy adults
This study looks at how your gut bacteria and the foods you eat affect your blood sugar after meals. You'll wear a small sensor to track your blood sugar for 10 days and provide stool samples.
Florianópolis, Santa CatarinaAges 18–60 - NCT06973408Recruiting
Diet and lifestyle study for weight management
This study tests whether a specific diet and behavior program can help people with overweight improve their health. You will be asked to follow a specific eating plan and eat certain foods provided by the researchers.
GothenburgAges 18–70 - NCT07420023Recruiting
Nutrition study for weight management and fullness
This study tests a special food product and meal plan to help people feel fuller longer and control appetite. It may help you understand how certain foods affect your body and weight.
CorkAges 18–45 - NCT07193927RecruitingPhase 2
Testing a probiotic mix for fatty liver disease (MASLD)
This trial tests whether a probiotic mixture can improve liver health in people with moderate fatty liver disease (MASLD). It looks at how the probiotic affects liver fat, inflammation, and metabolism.
Girona, GironaAges 18–75 - NCT06873165Recruiting
Gut bacteria treatment for fatty liver disease
This study tests whether a specially designed gut bacteria treatment can help people with fatty liver disease and related health issues like high blood sugar, high cholesterol, or high blood pressure. It aims to see if the treatment is safe and improves liver health.
TaipeiAges 18–70 - NCT06386094Recruiting
Fatty Liver Disease and Heart Function Study
This study checks how fatty liver disease (a condition where fat builds up in the liver) affects the heart. If you have this liver condition and are between 18 and 65, you may help doctors understand the link between liver health and heart function.
Chandigarh, ChandigarhAges 18–65 - NCT07090083Recruiting
Liver health and food support for children
This study tests whether providing fruit and vegetable vouchers to families with children who have fatty liver disease can improve liver health. Diet and lifestyle are key to managing this condition.
San Francisco, CaliforniaAges 6–17 - NCT07737340Recruiting
Metabolic liver disease in new HIV patients
This study looks at liver health in people newly diagnosed with HIV, before they start HIV treatment. It aims to understand early changes in the liver related to metabolism.
Ankara, AnkaraAges 18 years+ - NCT06363253Recruiting
Gut bacteria study in obesity and muscle loss
This study looks at the bacteria in your gut (the microbiome) to understand how they relate to obesity and muscle loss. Researchers will collect stool samples to analyze the gut bacteria, which may help find new ways to treat metabolic diseases.
SingaporeAges 21–99 - NCT07298213Recruiting
Corazones Unidos Study for liver health
This study looks at whether having a family member or close friend join you can help improve liver health in Mexican-origin adults with fatty liver disease. You and your support person will participate together.
Tucson, ArizonaAges 18 years+ - NCT07437157Recruiting
Hong Kong diabetes fatty liver disease study
This research study looks at people with type 2 diabetes to learn more about fatty liver disease. By joining, you may help doctors better understand how these conditions are linked and improve future care.
Hong Kong, New TerritoriesAges 18 years+ - NCT03569735Recruiting
Elderly health survey in Nanshan, Shenzhen
This study follows people age 65 and older in Nanshan to learn about health over time using surveys and health samples. It may help researchers understand what supports healthy aging in the community.
Shenzhen, GuangdongAges 65 years+ - NCT06506630Recruiting
Coenzyme Q10 for metabolic syndrome risk
This trial tests whether taking Coenzyme Q10, a natural supplement, can improve heart health markers in people who have or are at high risk for metabolic syndrome. Metabolic syndrome is a group of conditions like high blood sugar, high blood pressure, and belly fat that raise your risk for heart disease and diabetes.
ShenzhenAges 30–90 - NCT04873258Recruiting
Test a non-invasive tool to screen for fat-related liver disease
This study looks at a new non-invasive screening method to predict metabolic dysfunction–associated steatotic liver disease (MASLD), a condition where fat builds up in the liver. The goal is to help identify people who may be at risk without needing invasive tests.
London, LondonAges 18–80 - NCT03549754Recruiting
iCaReMe registry for adults with diabetes, blood pressure, or heart/kidney disease
This is a health “registry,” meaning it collects information about people living with common chronic conditions. It may help researchers better understand real-world health needs and outcomes for people with type 2 diabetes, high blood pressure, heart failure, and/or chronic kidney disease.
Fortaleza, CearáAges 18 years+ - NCT03386981Recruiting
Study of bone health patterns in healthy adult athletes
This study looks at what bone “profiles” look like in healthy adult athletes. It may help researchers better understand how normal bone health varies in people who are physically active.
MilanAges 18 years+ - NCT06824974Recruiting
Time-restricted eating for liver disease or cancer
This study tests whether combining time-restricted eating with healthy eating helps people with metabolic liver disease, cirrhosis, or early-stage liver cancer. If you are overweight and currently fast less than 12 hours at night, this diet approach might improve your health.
La Jolla, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for metabolic disease?
- Yes. Clin2 currently lists 364 recruiting metabolic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.