Clinical trials
Metabolic Disease clinical trials
Below are recruiting metabolic disease clinical trials, each written for real people, not researchers. We’re tracking 365 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05013944Recruiting
Join a patient registry to support future research
This trial is a “patient registry,” which collects health information over time to help researchers plan and run future studies. It may help by contributing your experience so new treatments can be tested more effectively.
Arlington Heights, IllinoisAges 18 years+ - NCT06339489Recruiting
Bone Health in Early Menopause Study
This study looks at how bone health changes in women with premature ovarian insufficiency (early menopause). It aims to understand the body's bone metabolism to help manage long-term health.
BeijingAges 18–39 - NCT06813508Recruiting
Liver cancer and transplant study for MASLD patients
This study looks at factors that predict liver cancer and the need for a liver transplant in people with a liver condition called MASLD (metabolic dysfunction-associated steatotic liver disease). The goal is to better understand the disease and improve care.
Bologna, BolognaAges 18 years+ - NCT06869486Recruiting
How insomnia affects DNA, heart health, and lifestyle
This study looks at how insomnia affects your DNA, heart health, metabolism, and daily habits. It includes different groups of people—healthy adults, athletes, older adults, university students, and people with metabolic syndrome—to compare the impact of sleep problems.
Ensenada, Estado de Baja CaliforniaAges 18–75 - NCT04414046RecruitingPhase 2
Stem cell transplant using T-cell cleanup for immune and metabolism disorders
This Phase 2 study tests a specialized stem cell transplant that removes certain “T-cells” (a type of immune cell) to treat children with serious immune system or inherited metabolic problems. The goal is to improve or stabilize disease by resetting the immune system and supporting the body’s function.
St. Petersburg, FloridaAges Up to 21 years - NCT05705804Recruiting
Comparing statins and ezetimibe for heart patients with metabolic syndrome
This trial tests if pitavastatin alone or with ezetimibe affects blood sugar differently than atorvastatin in people who have heart or blood vessel disease and metabolic syndrome but do not have diabetes.
SeoulAges Any age - NCT06054516Recruiting
Study of heart metabolism in ischemic heart disease using advanced imaging
This trial uses a special imaging technique (hyperpolarized MRSI) to study metabolism in the heart muscle of people with chronic heart failure caused by ischemic heart disease. It aims to help doctors better understand how the heart uses energy.
Aarhus, Central JutlandAges 18–90 - NCT03535142Recruiting
Fatty liver in people considering bariatric surgery
This study looks at how fatty liver disease may predict future liver health in people with severe weight gain. It compares people who are planning bariatric (weight-loss) surgery with similar people who are not, to better understand who may be at higher risk.
EsbjergAges 18 years+ - NCT04809688Enrolling by invitation
Study how berries affect metabolism and gut bacteria
This study looks at whether eating Saskatoon berries changes how your body uses energy (metabolism) and how your gut bacteria behave. It’s done in healthy people and may help researchers understand how foods could support overall health.
Winnipeg, ManitobaAges 18–75 - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT06203860Recruiting
Heart-focused clinic for diabetes and heart disease
This study is testing whether a special heart-focused clinic can help people with type 2 diabetes who also have heart or blood vessel problems. If you have both diabetes and a heart condition like prior heart attack, stroke, heart failure, or hard-to-control high blood pressure, this program may support your health.
Svendborg, Region SyddanmarkAges 19 years+ - NCT04912648Recruiting
Study of metabolic risk and androgens in Irish women
This study looks at how hormones called androgens may relate to “metabolic risk” (things like blood sugar and weight-related health) over time. It mainly needs healthy adult women who can avoid certain medications during the weeks before starting.
DublinAges 18 years+ - NCT06606678Enrolling by invitation
Physical activity for better metabolism and health
This study looks at how regular exercise can help improve your metabolism, lower inflammation, and support your gut health. If you're over 50 and can safely be active, this trial may be a good fit.
PoznanAges 50 years+ - NCT07314151Recruiting
TCM tools for inflammatory bowel disease
This study compares people with Crohn’s disease or ulcerative colitis to healthy volunteers to see if traditional Chinese medicine tools can help identify unique features of these conditions, like changes in tongue coating. It aims to improve how we diagnose and understand inflammatory bowel disease.
Taichung, NorthAges 18 years+ - NCT06944353Enrolling by invitation
Fatty liver risk screening in the emergency department
This study looks at fatty liver findings on emergency department scans. If you have fatty liver and were sent home from the ED, the study may help connect you to follow-up care and avoid future liver problems.
Chicago, IllinoisAges 18 years+ - NCT03951311Recruiting
Diet and lifestyle study for people with weaker heart pumping
This study looks at how metabolic changes, diet, and lifestyle patterns affect heart failure. It may help find ways to improve symptoms and health by targeting diet and daily habits.
Shanghai, Shanghai MunicipalityAges 14–90 - NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT06567990Recruiting
Type 2 diabetes and fatty liver: new tests for disease tracking
This study is looking for people with type 2 diabetes and fatty liver disease to find better ways to track how the disease progresses. They will use special tests (biomarkers) to see if the liver is getting worse over time.
DijonAges 40–80 - NCT06007404Recruiting
Understanding metabolism and inflammation in teens
This study looks at how metabolism and inflammation relate to diabetes risk in teenagers. It may help researchers understand why some teens develop type 2 diabetes.
Ann Arbor, MichiganAges 14–18 - NCT05859022Recruiting
Bariatric treatment methods compared for diabetes and metabolism
This trial compares a less invasive heart/artery-based bariatric treatment (bariatric arterial embolization) with standard weight-loss surgery to see how they affect metabolism and type 2 diabetes. You might be considered if you have obesity with type 2 diabetes and have not had prior bariatric surgery.
LisbonAges 18–75 - NCT07673822Enrolling by invitation
Heart, kidney, and metabolic disease study in Korea
This study looks at how common heart, kidney, and metabolic problems are in Korea by using health insurance records. It will help doctors understand how often these conditions happen together.
SeoulAges 19 years+ - NCT07436195Recruiting
Epigenetics and cell-free DNA in gestational diabetes study
This study looks at how changes in DNA (called epigenetics) might affect gestational diabetes in pregnancy. It aims to understand these changes using cell-free DNA from the mother and father.
Ulm, Baden-WurttembergAges 18 years+ - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT07287514Recruiting
Test of two oils on metabolism in adults with insulin resistance
This study compares an oil rich in linoleic acid (a type of omega-6 fat) against a blend oil to see which one better improves metabolism and heart health in people with insulin resistance. It may help if you have insulin resistance and at least one heart risk factor like belly fat, low good cholesterol, or high blood pressure.
Santiago, Santiago MetropolitanAges 20–60
Hear when a new Metabolic Disease trial opens
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Common questions
- Are there clinical trials for metabolic disease?
- Yes. Clin2 currently lists 365 recruiting metabolic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.