Clinical trials
Metabolic Effects clinical trials
Below are recruiting metabolic effects clinical trials, each written for real people, not researchers. We’re tracking 203 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06274749Recruiting
Urolithin A for blood sugar in adults 55+ with extra weight
This study tests if a natural supplement called Urolithin A can help improve how your body handles sugar (glucose) in healthy adults aged 55 and older who have a higher body weight. You would take a daily capsule and come in for tests including blood work, treadmill walks, and an MRI.
Baltimore, MarylandAges 55–100 - NCT07534241Recruiting
Reishi Mushroom for Fatty Liver Disease
This study tests whether reishi mushroom (a type of fungus) can improve liver health in people with metabolic dysfunction-associated fatty liver disease—a condition where fat builds up in the liver. Researchers want to see if this natural supplement can reduce liver inflammation and improve blood sugar and cholesterol levels.
LahoreAges 35–65 - NCT06765057RecruitingPhase 2/Phase 3
Probiotics for Depression and Metabolic Health
This trial tests whether taking a probiotic supplement can improve both depression symptoms and metabolic health (like waist size, blood sugar, and cholesterol) in people with major depression. It may be a good fit if you are already on an antidepressant and have signs of metabolic syndrome.
Riyadh, Riyadh RegionAges 18–65 - NCT07592013Enrolling by invitation
Ancestry Supplements for Fatty Liver Disease
This study tests whether a special supplement (made from cacao, nopal, and crickets) can help improve fatty liver disease in people with excess body fat. Fatty liver disease happens when fat builds up in the liver, and this trial investigates whether these natural ingredients can reduce that buildup.
Guadalajara, GuadalajaraAges 18–60 - NCT03407079RecruitingPhase 2
Study of sucralose’s effects on digestion of drugs
This study tests whether the sugar substitute sucralose changes how your body absorbs and breaks down certain medicines. You’d take sucralose or a placebo for 4 weeks, visit the clinic, and complete required samples and medicine doses during visits.
Bethesda, MarylandAges 18–60 - NCT04869098Recruiting
Evening protein shake for night shift workers’ metabolic health
This study tests whether eating a protein preload in the evening (often called a protein “shake/meal” before sleep) can improve metabolic health in night shift workers. It aims to see if this timing and protein intake helps measures related to metabolism while working nights.
Adelaide, South AustraliaAges 35–65 - NCT05838950Recruiting
Short high-intensity exercise program for cardiometabolic health
This trial studies whether a structured, short high-intensity exercise program can improve health markers related to weight, blood sugar, and blood fats in young adults with obesity. It may help you see if this kind of exercise leads to measurable health improvements.
Syracuse, New YorkAges 18–25 - NCT06061042Recruiting
Time-restricted eating for metabolic health
This study tests whether eating only during a specific time window each day can improve metabolic health in people with obesity and insulin resistance. If you have a high BMI and early signs of diabetes, this trial might help you understand a simple dietary change.
Amsterdam, North HollandAges 50–75 - NCT06315725Recruiting
Artificial sweeteners and blood sugar in type 1 diabetes
This study tests whether artificial sweeteners affect blood sugar levels in people with type 1 diabetes. If you use an insulin pump and have well-controlled diabetes, you may be able to join.
Montreal, QuebecAges 18–45 - NCT06613854RecruitingPhase 4
Early combination therapy for type 2 diabetes
This study tests if starting two newer diabetes drugs (empagliflozin and semaglutide) soon after diagnosis, along with metformin, helps control blood sugar better than metformin alone. It's for people diagnosed with type 2 diabetes in the last two years who are already taking a high dose of metformin.
LjubljanaAges 18–70 - NCT06916936Recruiting
Peanut butter study for gut health in kids
This study tests if eating peanut butter every day for a few weeks can improve how your body digests food and stays healthy. It's for kids in elementary or middle school who don't have nut allergies or certain stomach problems.
Tallahassee, FloridaAges 6–13 - NCT07065942Recruiting
Lactulose for gut health in diabetes with constipation
This study tests if a common stool softener called lactulose can improve gut health and metabolism in people with type 2 diabetes and long-term constipation. It aims to see if changing gut bacteria can help both digestion and blood sugar control.
BeijingAges 18–70 - NCT07179926Recruiting
Impact of pasireotide on bone health in acromegaly
This trial studies how pasireotide LAR—a drug that controls growth hormone levels—affects bone health in people with acromegaly whose disease is not well-controlled after 6 months of another therapy. It may help patients understand the bone benefits of switching to this treatment.
Rome, RMAges 18 years+ - NCT07401992RecruitingPhase 4
Semaglutide for psoriasis and weight management
This trial tests if semaglutide, a diabetes and weight-loss medication, can improve psoriasis symptoms and reduce inflammation. It may be an option for people with both psoriasis and overweight or obesity, with or without diabetes.
Monterrey, N.L.Ages 18 years+ - NCT07646197Recruiting
Peanut Consumption and Fatty Liver Disease in Adults
This study tests whether eating peanuts regularly can help improve fatty liver disease (a condition where fat builds up in the liver). You'll be asked to eat peanuts as part of your diet while researchers track changes in your liver health.
Detroit, MichiganAges 30–70 - NCT06885255Recruiting
Fasting and Exercise for Metabolic Syndrome
This study tests whether combining intermittent fasting with exercise can lower inflammation and improve your metabolism and gut health in people with metabolic syndrome.
Erlangen, BavariaAges 18–80 - NCT07000825Enrolling by invitation
Yerba mate extract for improving metabolic health in overweight adults
This trial tests whether a daily yerba mate extract can help reduce metabolic syndrome in overweight people. You would take the extract for a period while keeping your usual diet and activities.
Realeza, ParanáAges 40–65 - NCT06061926RecruitingPhase 2
Celery seed for metabolic syndrome
This trial tests whether celery seed can improve the key features of metabolic syndrome, such as blood sugar, cholesterol, and blood pressure. It may help people whose condition is not yet being treated with medication.
Guadalajara, JaliscoAges 30–60 - NCT07354438Recruiting
Antioxidant-rich diet for metabolic syndrome risk
This study tests whether eating more foods rich in antioxidants (like fruits and vegetables) can help lower your risk of metabolic syndrome, a condition that increases your chance of heart disease and diabetes. If you have a larger waist size and higher blood pressure, and you don't eat many fruits and vegetables, this trial may be a good fit.
Lahore, Punjab ProvinceAges 18–45 - NCT06158152Recruiting
AM3 supplement for metabolic syndrome pilot study
This study tests an oral supplement called AM3 in people with metabolic syndrome. It looks at whether the supplement can help improve sugar and fat levels in the blood.
MadridAges 18–75 - NCT05553093RecruitingPhase 4
Tirzepatide vs insulin for diabetes and brain effects
This study tests how tirzepatide and insulin glargine affect blood sugar, fat metabolism, and brain function in adults with type 2 diabetes. It may help researchers learn which treatment changes diabetes-related body and brain processes.
Nanjing, JiangsuAges 18–75 - NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT06712511Recruiting
Coffee's effect on energy and caffeine breakdown
This study looks at how coffee affects your body's energy use and how quickly you process caffeine. It may help explain why coffee affects people differently.
Shenzhen, GuangdongAges 18–40 - NCT06815237RecruitingPhase 2/Phase 3
Ketone supplement and alcohol effects on brain metabolism
This study looks at how a ketone supplement and alcohol affect your brain's metabolism. You will be asked to visit the lab, have an MRI, and possibly take the supplement or drink alcohol.
Philadelphia, PennsylvaniaAges 21–65
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Common questions
- Are there clinical trials for metabolic effects?
- Yes. Clin2 currently lists 203 recruiting metabolic effects studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic effects trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic effects trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.