Clinical trials
Metabolic Effects clinical trials
Below are recruiting metabolic effects clinical trials, each written for real people, not researchers. We’re tracking 188 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07179926Recruiting
Impact of pasireotide on bone health in acromegaly
This trial studies how pasireotide LAR—a drug that controls growth hormone levels—affects bone health in people with acromegaly whose disease is not well-controlled after 6 months of another therapy. It may help patients understand the bone benefits of switching to this treatment.
Rome, RMAges 18 years+ - NCT07065942Recruiting
Lactulose for gut health in diabetes with constipation
This study tests if a common stool softener called lactulose can improve gut health and metabolism in people with type 2 diabetes and long-term constipation. It aims to see if changing gut bacteria can help both digestion and blood sugar control.
BeijingAges 18–70 - NCT06916936Recruiting
Peanut butter study for gut health in kids
This study tests if eating peanut butter every day for a few weeks can improve how your body digests food and stays healthy. It's for kids in elementary or middle school who don't have nut allergies or certain stomach problems.
Tallahassee, FloridaAges 6–13 - NCT05838950Recruiting
Short high-intensity exercise program for cardiometabolic health
This trial studies whether a structured, short high-intensity exercise program can improve health markers related to weight, blood sugar, and blood fats in young adults with obesity. It may help you see if this kind of exercise leads to measurable health improvements.
Syracuse, New YorkAges 18–25 - NCT06765057RecruitingPhase 2/Phase 3
Probiotics for Depression and Metabolic Health
This trial tests whether taking a probiotic supplement can improve both depression symptoms and metabolic health (like waist size, blood sugar, and cholesterol) in people with major depression. It may be a good fit if you are already on an antidepressant and have signs of metabolic syndrome.
Riyadh, Riyadh RegionAges 18–65 - NCT06613854RecruitingPhase 4
Early combination therapy for type 2 diabetes
This study tests if starting two newer diabetes drugs (empagliflozin and semaglutide) soon after diagnosis, along with metformin, helps control blood sugar better than metformin alone. It's for people diagnosed with type 2 diabetes in the last two years who are already taking a high dose of metformin.
LjubljanaAges 18–70 - NCT03407079RecruitingPhase 2
Study of sucralose’s effects on digestion of drugs
This study tests whether the sugar substitute sucralose changes how your body absorbs and breaks down certain medicines. You’d take sucralose or a placebo for 4 weeks, visit the clinic, and complete required samples and medicine doses during visits.
Bethesda, MarylandAges 18–60 - NCT06885255Recruiting
Fasting and Exercise for Metabolic Syndrome
This study tests whether combining intermittent fasting with exercise can lower inflammation and improve your metabolism and gut health in people with metabolic syndrome.
Erlangen, BavariaAges 18–80 - NCT07000825Enrolling by invitation
Yerba mate extract for improving metabolic health in overweight adults
This trial tests whether a daily yerba mate extract can help reduce metabolic syndrome in overweight people. You would take the extract for a period while keeping your usual diet and activities.
Realeza, ParanáAges 40–65 - NCT06061926RecruitingPhase 2
Celery seed for metabolic syndrome
This trial tests whether celery seed can improve the key features of metabolic syndrome, such as blood sugar, cholesterol, and blood pressure. It may help people whose condition is not yet being treated with medication.
Guadalajara, JaliscoAges 30–60 - NCT07354438Recruiting
Antioxidant-rich diet for metabolic syndrome risk
This study tests whether eating more foods rich in antioxidants (like fruits and vegetables) can help lower your risk of metabolic syndrome, a condition that increases your chance of heart disease and diabetes. If you have a larger waist size and higher blood pressure, and you don't eat many fruits and vegetables, this trial may be a good fit.
Lahore, Punjab ProvinceAges 18–45 - NCT07710274Recruiting
Personalized Program for Insulin Resistance in Metabolic Syndrome
This pilot study tests a personalized program called PRISM to help improve how your body responds to insulin. If you have metabolic syndrome (a cluster of conditions like large waist size, high blood pressure, or high blood sugar) and insulin resistance, the study will use a continuous glucose monitor, smart ring, and food logging app to give you tailored feedback.
SingaporeAges 21–70 - NCT06158152Recruiting
AM3 supplement for metabolic syndrome pilot study
This study tests an oral supplement called AM3 in people with metabolic syndrome. It looks at whether the supplement can help improve sugar and fat levels in the blood.
MadridAges 18–75 - NCT05553093RecruitingPhase 4
Tirzepatide vs insulin for diabetes and brain effects
This study tests how tirzepatide and insulin glargine affect blood sugar, fat metabolism, and brain function in adults with type 2 diabetes. It may help researchers learn which treatment changes diabetes-related body and brain processes.
Nanjing, JiangsuAges 18–75 - NCT06712511Recruiting
Coffee's effect on energy and caffeine breakdown
This study looks at how coffee affects your body's energy use and how quickly you process caffeine. It may help explain why coffee affects people differently.
Shenzhen, GuangdongAges 18–40 - NCT07173504Recruiting
Continuous vs. intermittent tube feeding in ICU patients
This trial compares giving tube feeding continuously versus taking breaks to see which approach helps critically ill patients' metabolism better. It is for adults in the ICU who need a breathing tube and will be fed through a stomach tube.
Ede, GelderlandAges 18 years+ - NCT06827379Enrolling by invitation
Breathing exercise for muscle and nerve health in COPD
This trial tests whether a special breathing exercise (inspiratory muscle training) can improve how your muscles work and your body's automatic responses, like heart rate. It's a one-time session for people with stable COPD.
João Pessoa, ParaíbaAges 40–75 - NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT06883578Recruiting
Effect of a low valine diet on body weight and metabolism
This trial studies if a diet low in valine, a building block of protein, can help people with excess weight lose weight and improve their metabolic health. It may offer an alternative approach for weight loss.
Shanghai, Shanghai MunicipalityAges 16–80 - NCT07097506RecruitingPhase 2
Ketone drink for liver fat and health
This study tests whether a daily ketone ester drink can reduce liver fat and improve metabolism in people with excess liver fat. You may join if you are 18–40, have overweight or obesity, and your liver has extra fat.
St Louis, MissouriAges 18–40 - NCT06800872Recruiting
Vibration therapy for weight loss in teens
This trial tests if whole body vibration can help teenagers with obesity burn more energy while staying in a hospital program. It may offer an extra tool to support weight management.
Oggebbio, VerbaniaAges 13–18 - NCT07181655Recruiting
Fasting, calorie cutting, and exercise for metabolic syndrome
This study tests if combining intermittent fasting, calorie reduction, and physical activity can help manage metabolic syndrome (a group of risk factors that increase your chance of heart disease, stroke, and diabetes). If you have at least three of five specific health issues (like belly fat, high blood pressure, or high blood sugar) and are an adult aged 18 or older, you may be able to join.
Serdang, SelangorAges 18–80 - NCT07847684Recruiting
Hourly stair climbing for adults with prediabetes
This study tests whether short bursts of stair climbing every hour can improve blood sugar and blood vessel health in adults with prediabetes. If you join, you'll complete three different activity schedules to see which helps most.
St Louis, MissouriAges 18–69 - NCT07550023Recruiting
How Different Dietary Fats Affect Your Gut Health
This study examines how different types of dietary fats influence the bacteria in your gut and how your body processes nutrients. By participating, you'll help researchers understand the link between fat intake and digestive health in healthy adults.
GlasgowAges 20–50
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Common questions
- Are there clinical trials for metabolic effects?
- Yes. Clin2 currently lists 188 recruiting metabolic effects studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic effects trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic effects trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.