Clinical trials
Metabolic Effects clinical trials
Below are recruiting metabolic effects clinical trials, each written for real people, not researchers. We’re tracking 201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05652478RecruitingPhase 2
How HIV prevention drugs affect metabolism in healthy people
This study tests how certain HIV prevention drugs affect the body's metabolism (how it uses energy) in healthy people. It aims to understand side effects before these drugs are used more widely, which could help make future treatments safer.
Bethesda, MarylandAges 18–55 - NCT05802121RecruitingEarly Phase 1
Testing a gut bacteria supplement side effects during prostate hormone therapy
This early-phase study looks at how changing gut bacteria (especially Akkermansia) affects metabolic side effects in men starting prostate hormone therapy (ADT). It may help researchers understand how to reduce or manage side effects for people on ADT.
London, OntarioAges 18 years+ - NCT06624462Recruiting
Meta Care Clinic for weight and health in severe mental illness
This study tests a special clinic that helps people with schizophrenia or bipolar disorder manage their weight and metabolic health while taking antipsychotic medication. It focuses on improving overall health with practical support.
Glostrup Municipality, Capital RegionAges 18–45 - NCT06059651Recruiting
Bariatric Surgery and its Effects on Fat, Immune Cells, and Cancer
This study looks at how bariatric (weight-loss) surgery affects fat metabolism, immune cells, and cancer risk in women with severe obesity and high cholesterol. If you are a woman aged 35–60, White or Black, with a BMI of 40 or higher and high triglycerides or LDL, you may be eligible.
Baton Rouge, LouisianaAges 35–60 - NCT06867419Recruiting
Metabolic effects on fatty liver disease score
This study looks at how certain features of your metabolism affect a simple score (called the FAST score) in people with fatty liver disease (MASLD). It aims to help doctors better understand and manage the condition.
Tanta, GharbyeaAges 18 years+ - NCT02646475RecruitingPhase 1
Study angiotensin medicine to improve metabolism in obesity
This Phase 1 study tests how a medication that affects the body’s angiotensin system (angiotensin-(1-7)) changes metabolism in adults with obesity, insulin resistance, and high blood pressure. It may help researchers understand whether this approach can improve blood sugar/insulin function and related body changes.
Nashville, TennesseeAges 18–60 - NCT07686601Enrolling by invitation
Shockwave therapy for belly fat
This study tests whether a sound-wave device (shockwave therapy) applied to your belly can help shrink fat and improve body measurements. It is for adults who have stubborn belly fat and are otherwise healthy.
Shibīn al Kawm, MenofyiaAges 18 years+ - NCT05859022Recruiting
Bariatric treatment methods compared for diabetes and metabolism
This trial compares a less invasive heart/artery-based bariatric treatment (bariatric arterial embolization) with standard weight-loss surgery to see how they affect metabolism and type 2 diabetes. You might be considered if you have obesity with type 2 diabetes and have not had prior bariatric surgery.
LisbonAges 18–75 - NCT06925997RecruitingEarly Phase 1
Bile acids after gastric bypass: metabolic effects study
This trial looks at how bile acids affect metabolism in people who have had gastric bypass surgery. It compares three groups: those who had diabetes before surgery, those without diabetes, and those with type 2 diabetes.
HvidovreAges 18 years+ - NCT07287514Recruiting
Test of two oils on metabolism in adults with insulin resistance
This study compares an oil rich in linoleic acid (a type of omega-6 fat) against a blend oil to see which one better improves metabolism and heart health in people with insulin resistance. It may help if you have insulin resistance and at least one heart risk factor like belly fat, low good cholesterol, or high blood pressure.
Santiago, Santiago MetropolitanAges 20–60 - NCT06820281RecruitingPhase 2
Tirzepatide for type 1 diabetes: a metabolism study
This study tests if tirzepatide, a medicine that helps lower blood sugar and manage weight, is safe and effective for people with type 1 diabetes who are overweight or have obesity. You must already use an automated insulin pump system.
Sydney, New South WalesAges 18–65 - NCT06623032Recruiting
Medium-chain fatty acids in MCADD patients and healthy volunteers
This trial tests how medium-chain fatty acids (a type of fat found in coconut oil) affect metabolism in people with MCADD, a genetic condition that affects fat breakdown, compared to healthy people. The results may help guide dietary advice for those with MCADD.
CopenhagenAges 18–80 - NCT05722873Recruiting
Study intermittent fasting and its effects on metabolism
This study looks at how intermittent fasting affects your body's “metabolism” (how you use food and manage blood sugar/fats). It may help researchers understand whether this eating pattern changes metabolic health in people at higher risk for type 2 diabetes.
Pittsburgh, PennsylvaniaAges 21–45 - NCT07024238Enrolling by invitation
Short-chain fatty acid supplement for kidney transplant patients
This study tests whether taking a short-chain fatty acid (a type of fiber-like substance) supplement can improve gut health in people who have had a kidney transplant. It may help keep the transplant working well.
Martin, SlovakiaAges 18 years+ - NCT05211375RecruitingPhase 3
Compare two weight-loss surgeries for type 2 diabetes control
This Phase 3 trial compares sleeve gastrectomy versus a different bypass-style operation to improve blood sugar in adults with type 2 diabetes. It may help some people lower blood sugar and diabetes medication needs, but you must meet specific safety and health criteria.
Seongnam-siAges 18 years+ - NCT06174116RecruitingPhase 4
Adding lumateperone to clozapine for schizophrenia
This trial tests whether adding lumateperone, an antipsychotic medication, to clozapine can improve metabolic health in people with schizophrenia. It aims to see if this combination helps with weight, blood sugar, and cholesterol levels.
Worcester, MassachusettsAges 18–65 - NCT06309563Recruiting
Essential amino acid diet for severe obesity
This study tests whether replacing some foods with essential amino acids (protein building blocks) can improve metabolism in people with severe obesity. It aims to find a non-surgical way to boost weight loss.
Oggebbio, VerbaniaAges 45–65 - NCT06725511Recruiting
Wellness program for employees with metabolic syndrome
This study tests a wellness program designed for employees with metabolic syndrome, a cluster of conditions like high blood pressure and high blood sugar. The program aims to improve health through outreach and support.
Secaucus, New JerseyAges 21 years+ - NCT06851676Recruiting
Testing mineral water's effects on bone and muscle health
This trial tests if drinking Fonte Fausta® mineral water can help improve bone and muscle health in people with weak bones (osteopenia or osteoporosis). Researchers want to see if this water has special benefits beyond regular water.
Naples, ItalyAges 65 years+ - NCT07025213Recruiting
Exercise and diet study for endometrial cancer before surgery
This study tests whether combining exercise with a special diet can improve how your body processes energy (metabolism) before you have surgery to remove the cancer. It is for people with early-stage endometrial cancer who haven't yet started treatment.
México, TlalpanAges 18–65 - NCT07119424Recruiting
SGLT2 inhibitor study for older adults
This study looks at how a class of diabetes and kidney drugs called SGLT2 inhibitors affect older adults. It aims to understand the benefits for your kidneys and metabolism.
Milan, MilanAges 65 years+ - NCT07183488Recruiting
Short-chain fatty acids and metabolism in healthy adults
This trial tests how short-chain fatty acids (compounds made when gut bacteria digest fiber) affect metabolism in healthy people. It may help researchers understand how these natural substances can improve health.
Copenhagen, Copenhagen NAges 18–40 - NCT07213245Recruiting
Short-term effects of ultra-processed foods on metabolism
This study tests how eating ultra-processed foods for a short time affects your metabolism. If you are a healthy adult with a normal BMI, no diabetes, and no major dietary restrictions, you may be able to participate.
GothenburgAges 18–50 - NCT07463495Recruiting
Testing a supplement called tributyrin for weight and metabolism
This trial tests whether a supplement called tributyrin, which may help with metabolism and weight loss, is safe and effective for people with obesity. You might qualify if you have a BMI between 30 and 45 and are not taking diabetes medications.
Aarhus NAges 18 years+
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Common questions
- Are there clinical trials for metabolic effects?
- Yes. Clin2 currently lists 201 recruiting metabolic effects studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic effects trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic effects trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.