Clinical trials
Metabolic Syndrome clinical trials
Below are recruiting metabolic syndrome clinical trials, each written for real people, not researchers. We’re tracking 214 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04893226Recruiting
Time-restricted eating for postmenopausal metabolic risk
This trial studies whether limiting when you eat each day can improve blood sugar and other health markers in postmenopausal women with prediabetes or metabolic risk factors. It may help your body’s metabolism if your sleep and daily routine can stay fairly consistent.
Lexington, KentuckyAges 45–65 - NCT04841057Enrolling by invitation
Study of blood and stool changes after weight-loss surgery
This study looks at how your body’s metabolism changes after a specific weight-loss surgery (gastric bypass). It may help researchers better understand what to expect and how to tailor care, while requiring blood draws and stool samples before and after surgery.
Columbia, MissouriAges 18–80 - NCT04708431Recruiting
Study of health and wellbeing in people with androgen insensitivity
This study looks at the long-term health and wellbeing of people with androgen insensitivity, a genetic condition that affects how the body responds to androgens (male-type hormones). It may help your care team understand what to watch for over time and improve future guidance for patients and families.
Bethesda, MarylandAges 8–99 - NCT04634591Recruiting
Weight-loss surgery study for people with severe obesity
This trial studies bariatric (weight-loss) surgery and how well it helps people reach and keep a healthier weight. You may qualify if you have severe obesity and have not been able to maintain weight loss with other attempts, and if you can safely follow the study plan.
Bialystok, Podlaskie VoivodeshipAges 18 years+ - NCT04583514Recruiting
Overfeeding study to see how body fat can expand
This trial studies how your body’s fat tissue changes when you eat extra food for 8 weeks. It may help researchers understand why some people gain more weight than others.
Baton Rouge, LouisianaAges 18–42 - NCT03794531Recruiting
Study of health, stress, and lifestyle changes in Puerto Rico
This study looks at how people’s health, day-to-day stress, and living conditions in Puerto Rico change over time. You might help researchers understand what trends are happening and what could be improved.
San JuanAges 30–75 - NCT03128996RecruitingPhase 1/Phase 2
Bone marrow transplant with lighter chemo for non-cancer illnesses
This early-phase study tests a safer “lighter” conditioning chemo plan before a bone marrow transplant for people with non-cancer blood and immune disorders. It aims to reduce transplant risk while using donor marrow that does not match perfectly in the HLA type.
New Haven, ConnecticutAges 1 day–21 years - NCT01084967Recruiting
Study genes behind obesity in young people from East China
This study looks at how genes may contribute to obesity in young people living in East China. If you meet the weight and background criteria and can consent, you may be able to help researchers learn more and improve care for obesity.
Shanghai, Shanghai MunicipalityAges 14–30 - NCT01143480Recruiting
Testing how the body responds to endotoxin
This study checks how your immune system (your body’s defense system) reacts to a controlled substance that triggers inflammation. It may help researchers understand why some people have stronger or weaker inflammatory responses.
Research Triangle Park, North CarolinaAges 18–100 - NCT02646475RecruitingPhase 1
Study angiotensin medicine to improve metabolism in obesity
This Phase 1 study tests how a medication that affects the body’s angiotensin system (angiotensin-(1-7)) changes metabolism in adults with obesity, insulin resistance, and high blood pressure. It may help researchers understand whether this approach can improve blood sugar/insulin function and related body changes.
Nashville, TennesseeAges 18–60 - NCT07142603Recruiting
Appetite and different proteins in PCOS
This trial tests how different sources of protein (plant vs. animal) affect appetite in women with PCOS. It may help you understand your hunger and fullness responses and guide diet choices.
Fayetteville, ArkansasAges 18–50 - NCT01962415RecruitingPhase 2
Reduced-intensity stem cell transplant for non-cancer disorders
This trial tests whether a gentler (reduced-intensity) conditioning treatment before a stem cell transplant works for non-cancer diseases. It uses specific donor stem cell matches and checks heart, lung, liver, and kidney function to help lower transplant stress while still aiming for benefit.
Pittsburgh, PennsylvaniaAges 2 months–55 years - NCT04528355Recruiting
Study of hospital data after stem cell transplant for non-cancer illness
This study collects medical information from people with certain non-cancer conditions who receive a stem cell transplant. It may help doctors better understand transplant outcomes and care, since the study focuses on data collection rather than adding new treatment.
Pittsburgh, PennsylvaniaAges 2 months–60 years - NCT03911297Recruiting
DAISy-PCOS study of hormone and metabolism in suspected PCOS
This study looks at hormone levels and metabolism in people who may have polycystic ovary syndrome (PCOS). It aims to better understand why PCOS happens, which could help improve future diagnosis and treatment.
Birmingham, West MidlandsAges 18–70 - NCT06366230RecruitingPhase 1/Phase 2
Adding urea to final dialysis fluid
This trial tests adding urea to the final dialysis fluid for people with very high urea levels. It aims to make dialysis safer and more effective for those who need it urgently.
San Francisco, CaliforniaAges 18 years+ - NCT06320782Enrolling by invitation
Diet and belly fat study for overweight adults
This study tests how different diets affect belly fat, thigh muscle, and heart health in people who are overweight. It might help you find a way to eat that improves your health.
Recife, PernambucoAges 20 years+ - NCT02356653RecruitingEarly Phase 1
Stem cell transplant help for children lacking a matching sibling
This expanded-access study offers a specific type of stem cell transplant preparation that removes certain immune cells (CD3 and CD19) from donor stem cells. It is for children who need a transplant but do not have a fully matched sibling donor and whose team cannot use the hospital’s usual matching device protocol.
Philadelphia, PennsylvaniaAges Up to 30 years - NCT07317076Recruiting
Magnetic device study for stomach and bowel blockages
This trial tests a new magnetic device that creates a connection between parts of your stomach or small intestine without needing stitches, for people with certain blockages or digestive issues.
Westmount, QuebecAges 18 years+ - NCT07714499Recruiting
Energy use in healthy people vs. those with intestinal failure
This study looks at how the body uses energy (calories) in people with intestinal failure compared to healthy controls. The results may help improve nutritional care.
LjubljanaAges 18–65 - NCT05586802RecruitingPhase 3
Balancing sex hormones to improve metabolism and fertility in Klinefelter
This study tests whether adjusting sex-hormone levels can improve body metabolism and reproductive hormone balance in people with Klinefelter syndrome. Depending on the design, you may be looking at fertility preservation and/or metabolic health.
LausanneAges 16–65 - NCT07170527Recruiting
Metabolic signs, recovery, and physical function after ICU stay
This study looks at whether certain molecules in the blood (metabolic signatures) are linked to how well people recover physically after a serious illness requiring intensive care. By understanding these links, doctors might be able to better predict and support recovery.
Ede, GelderlandAges 18 years+ - NCT03016806Recruiting
Umbilical cord blood transplant from unrelated donors
This trial studies transplanting healthy blood-forming cells from an umbilical cord blood donor who is not related to you. It may help people with certain blood cancers, immune disorders, or other serious diseases when a standard transplant plan is needed.
Rochester, New YorkAges 2 months–75 years - NCT06533007Enrolling by invitation
How PDE3B affects metabolism in healthy adults
This study looks at how a protein called PDE3B affects your body's metabolism (how it uses energy). It may help researchers understand weight and insulin resistance better, which could lead to new treatments.
CambridgeAges 21–75 - NCT02602769Recruiting
Testing blood traits in children with ROHHAD syndrome
This trial studies children with ROHHAD syndrome to better understand their body chemistry and other blood features. The results may help researchers learn what drives the condition and how it might be tracked over time.
Boston, New YorkAges 2–20
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Common questions
- Are there clinical trials for metabolic syndrome?
- Yes. Clin2 currently lists 214 recruiting metabolic syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.