Clinical trials
Microbiome clinical trials
Below are recruiting microbiome clinical trials, each written for real people, not researchers. We’re tracking 346 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07520461Recruiting
Diet Changes for Ulcerative Colitis Based on Gut Bacteria
This study tests whether a special diet designed to improve your gut bacteria can help control mild ulcerative colitis. You'll receive prepared meals and follow the diet for several weeks to see if it reduces inflammation in your colon.
Minneapolis, MinnesotaAges 18 years+ - NCT07515430Enrolling by invitation
Gut Bacteria and Cancer Symptoms in Children With Leukemia
This study looks at how the bacteria living in your child's gut may affect cancer-related symptoms (like nausea, fatigue, or pain) during leukemia treatment. Researchers will collect stool samples and track symptoms to understand this connection better.
Guangzhou, GuangdongAges 5–18 - NCT07501455Recruiting
Studying toothpaste and mouth rinse effects on gum inflammation
This study tests whether using a certain toothpaste and mouth rinse can reduce gum inflammation (gingivitis) better than brushing alone. It is for people with mild to moderate gum disease who have not used tobacco or certain medications recently.
Somerville, MassachusettsAges 18–60 - NCT06171360Recruiting
Gut bacteria and CDK4/6 inhibitor treatment in breast cancer
This study looks at how gut bacteria affect response to a type of targeted therapy (CDK4/6 inhibitors) combined with hormone therapy in breast cancer that is hormone receptor-positive and HER2-negative. It may help find out why some people respond better to treatment and could lead to better personalized care.
BrusselsAges 18–100 - NCT07483502Recruiting
Pre-surgery gut health supplement study for heart patients
This trial tests whether taking a gut health supplement (WellBiome) for six weeks before heart surgery can improve recovery and save the NHS money. It compares the supplement to a placebo (a pill with no active medicine).
Hull, East Riding Of YorkshireAges 50–80 - NCT07477470Recruiting
Fiber supplement for stress and mood
This study tests whether a daily fiber supplement can improve mood, memory, and gut health in stressed adults. It lasts a few weeks and involves questionnaires and samples.
LondonAges 18–50 - NCT06526689Recruiting
Lung health and germs in people exposed to TB
This study looks at how the immune system and natural germs in the lungs work in people who have recently been in close contact with someone with active tuberculosis (TB). It aims to better understand how the body responds to TB exposure.
Oxford, OxfordshireAges 18–65 - NCT07471373Recruiting
Pesticides and infertility study in endometriosis
This study looks at how pesticides might affect fertility in women with endometriosis, focusing on stress markers and gut/genital bacteria. You will provide samples and answer questions so researchers can compare women with and without endometriosis.
SalouëlAges 18–43 - NCT07453823Recruiting
Synbiotic for gut health in overweight adults
This trial tests a combination supplement (a synbiotic) to see if it can improve gut function and gut bacteria in middle-aged and older adults who are overweight and have constipation. If eligible, you take the supplement daily and report how your digestion feels.
Cork, BlackpoolAges 50–70 - NCT07457723RecruitingPhase 2
Gut health and metabolism study
This study tests whether a supplement can improve metabolic health by changing the bacteria in your gut. It looks at how your body processes food and energy.
Brisbane, QueenslandAges 18 years+ - NCT06100211Recruiting
HIV, gut health, and switching HIV meds study
This study looks at how changing your HIV medication affects the bacteria in your gut. You'll provide two stool samples so researchers can see what changes happen.
Manchester, Greater ManchesterAges 18 years+ - NCT07456579Enrolling by invitation
Alcohol and cannabis use in pregnancy
This study looks at alcohol and cannabis use during pregnancy by asking new mothers about their habits and testing newborn stool samples (meconium). The goal is to understand how common these substances are among pregnant women in Slovenia and how they might affect babies.
LjubljanaAges Any age - NCT06793137RecruitingPhase 2
Antibiotics before surgery for advanced rectal cancer
This trial tests if taking antibiotics before standard treatment can improve outcomes for people with advanced rectal cancer that requires surgery.
São Paulo, São PauloAges 18 years+ - NCT07446205Recruiting
Poi for Mama: a study to reduce gestational diabetes risk
This pilot study tests whether eating poi (a traditional Hawaiian food made from taro) can improve the health of your gut bacteria and lower the risk of gestational diabetes during pregnancy. It is open to pregnant women who live on the windward side of O'ahu and are in their second trimester.
Honolulu, HawaiiAges 18 years+ - NCT07437911Recruiting
Can a Supplement Help with Nutrient Gaps for GLP-1 Users?
This study tests whether a daily supplement can help fill nutrient gaps and improve gut health for people who are already taking GLP-1 weight-loss medications (like Ozempic or Wegovy). Participants must be on a stable dose for at least 8 weeks and be generally healthy without other chronic conditions.
Santa Monica, CaliforniaAges 18–59 - NCT06356012RecruitingPhase 4
Imiquimod for high-risk HPV cervical lesions
This trial tests if imiquimod cream can help clear high-grade cervical lesions caused by high-risk HPV. It may be an option for people who want to avoid surgery.
BarretosAges 25–45 - NCT07443917Recruiting
Study of Treponema Parvum in gum disease patients
This study looks for a specific bacteria called Treponema Parvum in the gums of people with periodontitis (severe gum disease). It aims to understand if this bacteria is linked to gum disease and could help improve future treatments.
BaghdadAges 30 years+ - NCT07443280Recruiting
Gut health supplement study for dialysis patients
This trial tests whether a special blend of probiotics and prebiotics (called a synbiotic) can improve gut health and reduce harmful waste products in the blood for people on hemodialysis.
Taichung, Wuqi DistrictAges 18 years+ - NCT06813521Recruiting
Antidandruff lotion study for scalp microbiome rebalance
This study tests a new antidandruff lotion designed to restore the natural balance of microbes on your scalp. If you have moderate to severe dandruff and are generally healthy, this trial may help improve your dandruff with a specially formulated product.
LisbonAges 18–60 - NCT07414498Recruiting
Bacteria in gum surgery for implant and tooth infections
This study looks at the bacteria living in deep gum pockets around implants or teeth during different types of gum surgery. It may help determine which surgical approach is best for your kind of gum infection.
Münster, North Rhine-WestphaliaAges 18–80 - NCT05099315Recruiting
Gut microbiome study in adults with severe eczema
This trial studies the gut microbiome in people with moderate to severe atopic dermatitis (eczema) who are starting or already receiving systemic (whole-body) treatment. It may help researchers understand what changes in gut bacteria are linked to eczema and to treatment response.
Berlin, State of BerlinAges 18 years+ - NCT07402226Recruiting
Diet study for bloating with scleroderma
This study tests whether a special diet can help reduce bloating and stomach discomfort in people with scleroderma (systemic sclerosis). You'll follow a specific meal plan to see if it improves your digestive symptoms.
Ann Arbor, MichiganAges 18 years+ - NCT06318507Recruiting
Gut Bacteria and Immunotherapy for Triple-Negative Breast Cancer
This study looks at how bacteria in your gut might affect the way your body responds to immunotherapy for triple-negative breast cancer. It focuses on women who are overweight or obese and are about to start treatment with pembrolizumab before surgery.
Baton Rouge, LouisianaAges 18 years+ - NCT06831539RecruitingPhase 1
How bowel prep affects gut bacteria recovery
This study looks at how the bowel preparation medicine (PEG) used before a colonoscopy affects the bacteria living in your gut and how well they recover afterward. Healthy volunteers will take the bowel prep and provide stool samples to help researchers understand this process.
Montreal, QuebecAges 18–70
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Common questions
- Are there clinical trials for microbiome?
- Yes. Clin2 currently lists 346 recruiting microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.