Clinical trials
Microbiome clinical trials
Below are recruiting microbiome clinical trials, each written for real people, not researchers. We’re tracking 346 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07388264Recruiting
Probiotic for bloating and gut health
This study tests a probiotic (a good bacteria) called Weizmannia coagulans to see if it helps reduce bloating and improves gut health. Researchers will check how your digestion changes by looking at your stool and gut bacteria.
Saint Charles, MissouriAges 18–50 - NCT06837272Recruiting
Gut health and brain health in Alzheimer's disease
This study looks at how the bacteria in your gut might be connected to memory and thinking problems in Alzheimer's disease. It may help us understand if changes in the gut can affect brain health.
Jining, ShandongAges 60–80 - NCT07365514RecruitingPhase 1
Blackcurrants study for bone health in postmenopausal women
This trial tests if taking a blackcurrant supplement can help maintain bone density and reduce osteoporosis risk in postmenopausal women. You will take daily capsules and provide blood, stool, and bone scan samples over the study period.
Storrs, ConnecticutAges 45–70 - NCT04970446RecruitingPhase 1/Phase 2
Fecal transplant to restore gut microbes in Crohn’s
This Phase 1/2 study tests whether a fecal microbiome transplant (FMT) can reduce active inflammation in people with Crohn’s disease. It’s designed for people who currently have signs of active bowel inflammation and can attend regular procedure visits.
Melbourne, VictoriaAges 18–70 - NCT06545123Recruiting
How different exercises affect gut health in older adults with muscle loss
This study looks at how different types of exercise can change the bacteria in your gut for older adults who have muscle loss (sarcopenia). You will be assigned to one of two exercise programs to see which one helps your muscles and gut health the most.
PortoAges 60 years+ - NCT07351175Recruiting
Can a special cheese lower cholesterol by changing gut bacteria?
This study tests whether eating a type of aged cheese can help lower cholesterol by affecting the good bacteria in your gut. It is for people who regularly eat cheese, have slightly high cholesterol, and are generally healthy.
ReadingAges 18–65 - NCT06699199RecruitingPhase 4
Testing silver diamine fluoride on mouth bacteria in kids
This study tests if a liquid medicine (silver diamine fluoride) painted on baby teeth cavities can change the bacteria in a child's mouth. It is for healthy children ages 4–10 with an open cavity.
Jeddah, Mecca RegionAges 4–12 - NCT07329595Recruiting
Tracking gut bacteria changes after severe burns
This study looks at how severe burns change the bacteria in your gut and your immune system. It will track these changes to better understand recovery and find new ways to help healing.
Debrecen, Hajdú-BiharAges 18–65 - NCT06172764RecruitingPhase 4
Vitamin D for early cavities: a saliva study
This study tests whether vitamin D supplements can help improve the health of your mouth by looking at changes in saliva and the bacteria that cause cavities. If you have early cavities and low vitamin D, you may be able to join.
Karachi, SindhAges 12–50 - NCT06870981Recruiting
Optimizing nutrition and milk in infants (Opti-NuM)
This study looks at stored information and samples from babies who were part of earlier MaxiMoM nutrition trials. It aims to learn more about how nutrition and milk feeding affect infant health.
Palo Alto, CaliforniaAges 1 hour–3 weeks - NCT07316465Recruiting
Tracking immune markers in newborns at risk for eczema
This study follows newborns for two years to see how their immune system develops, especially if they have a family history of eczema, asthma, or hay fever. Researchers want to learn if certain immune markers appear early in babies who later develop eczema.
Jette, Brussels CapitalAges 1 hour–2 years - NCT06495190Recruiting
Blueberries, exercise, and memory in older adults
This study tests whether eating blueberries and doing regular exercise can help with mild memory decline. You will be assigned to one of four groups (blueberries + walking, blueberries + stretching, or similar combos) for 12 weeks.
Kannapolis, North CarolinaAges 65–85 - NCT07308808RecruitingEarly Phase 1
Safety of a live bacteria solution for bladder infections
This trial tests if putting a live bacteria called Lactobacillus crispatus into the bladder is safe for people with spinal cord injury and neurogenic lower urinary tract dysfunction. It may help prevent urinary tract infections without antibiotics.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07311083Recruiting
Lifestyle program for triple-negative breast cancer patients
This study tests a lifestyle program (diet, exercise, and support) for women with triple-negative breast cancer who are getting chemotherapy plus immunotherapy before surgery. The goal is to see if healthy habits can help during treatment.
Essen, North Rhine-WestphaliaAges 18–75 - NCT05846620Recruiting
Study of lung immune cells and the gut microbiome
This study looks at how immune cells in the lungs relate to the microbiome (the helpful microbes in the gut) in healthy adults. It may help scientists understand what affects lung health and immune balance.
HvidovreAges 40–75 - NCT05795257Recruiting
Studying lung immune cells and gut microbes in ARDS
This trial studies how immune cells in the lungs and gut microbes (your microbiome) change during ARDS and how these changes relate to your outcomes. It may help researchers better predict and treat ARDS by learning what’s going on in the lungs and body systems.
HvidovreAges 18 years+ - NCT07296965Recruiting
Oral bacteria in carotid artery plaque study
This study looks at the bacteria living in your mouth and whether they are linked to plaque buildup in the carotid artery (the main artery in your neck). If you are already scheduled for surgery to remove that plaque, the researchers will take samples from your mouth and the plaque to compare them.
BudapestAges 18 years+ - NCT04579900Recruiting
Study how gut microbes affect type 2 diabetes risk
This study looks at how differences in gut microbes may relate to risk of developing type 2 diabetes. It may help researchers understand who is more likely to develop diabetes, and why.
Québec, QuebecAges 18–60 - NCT04305808Recruiting
Study of gut, bladder, and vaginal bacteria in recurrent UTIs
This study looks at the bacteria living in the vagina, urine tract, and stool to learn why some women get repeated urinary tract infections (UTIs). The results may help doctors better prevent or treat UTIs in the future.
Jerusalem, JerusalemAges Any age - NCT05640700Recruiting
Study of vaginal microbiome in HPV-related early cell changes
This study looks at the vaginal “microbiome” (the normal germs and bacteria in the vagina) in people who have had abnormal Pap smear or colposcopy results related to HPV. It may help doctors understand what to monitor and how to better identify early, pre-cancer changes in the cervix.
JerusalemAges 25–70 - NCT07280091Recruiting
Skin and gut bacteria in Netherton syndrome
This study looks at the bacteria on the skin and in the gut of people with Netherton syndrome, a condition that affects the skin barrier and often causes allergies. It also compares these findings to healthy volunteers to understand how the microbiome might be different.
Paris, Île-de-France RegionAges 10 years+ - NCT06885255Recruiting
Fasting and Exercise for Metabolic Syndrome
This study tests whether combining intermittent fasting with exercise can lower inflammation and improve your metabolism and gut health in people with metabolic syndrome.
Erlangen, BavariaAges 18–80 - NCT06423508Recruiting
Testing stool storage methods and gut bacteria differences
This trial will study how different storage methods affect stool samples for gut bacteria analysis. It aims to understand differences in gut bacteria between people over time. Participation involves providing stool samples.
Vienna, State of ViennaAges 18–70 - NCT07259681Recruiting
A study on gut health, pelvic side effects, and ozone therapy
This study looks at the bacteria in your gut (gut microbiome) to see how it is affected by pelvic side effects from cancer treatment, and whether ozone therapy might help. It compares patients who have chronic pelvic side effects and are treated with ozone (cases) to those who do not have these side effects (controls).
Las Palmas de Gran Canaria, Las PalmasAges 18 years+
Hear when a new Microbiome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for microbiome?
- Yes. Clin2 currently lists 346 recruiting microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.