Clinical trials
Microbiome clinical trials
Below are recruiting microbiome clinical trials, each written for real people, not researchers. We’re tracking 346 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06778083Recruiting
Antibiotic to prevent STIs and its effect on resistance
This study looks at taking doxycycline to prevent sexually transmitted infections (STIs) in men who have sex with men. It focuses on how this approach might affect the body's resistance to antibiotics.
LondonAges 18 years+ - NCT07250100Recruiting
Study of gut bacteria in pancreatic cancer and precancer
This study looks at the bacteria living in your gut and pancreas to understand how they might affect pancreatic cancer and precancerous changes. It is for people who are already scheduled for an endoscopic procedure to look at or treat a pancreatic lesion.
Herlev, Capital RegionAges 18 years+ - NCT07255430Recruiting
Airway bacteria study for children with PBB
This study looks at the bacteria in the airways of children with Protracted Bacterial Bronchitis (PBB), a long-lasting cough caused by bacteria. It aims to understand how these bacteria affect the condition, which could lead to better treatments.
EdegemAges Up to 5 years - NCT07236125Recruiting
Nitrate-rich foods and mouth bacteria in children with high blood pressure
This study looks at how eating nitrate-rich vegetables (like spinach and beets) might affect the helpful bacteria in your child's mouth and their blood pressure. It's for children ages 10 to 18 who have primary hypertension (high blood pressure not caused by another condition) and are otherwise healthy.
Istanbul, FatihAges 10–18 - NCT07225153Recruiting
Goat milk formula vs. undiluted goat milk for infant growth
This trial tests whether a goat milk-based formula helps infants who cannot breastfeed grow as well as those who drink undiluted goat milk. It focuses on babies living in the Matiari District whose families have access to goat milk.
Matiāri, SindhAges 2 months–2 months - NCT07218640Recruiting
Stool sampling study with chia seeds for adults
This trial asks adults to eat chia seeds and provide stool samples several times a week. Researchers want to learn more about digestion and gut health by studying the samples.
Ambler, PennsylvaniaAges 18–50 - NCT07212400Recruiting
Stool donor study: dairy phages, antibiotics, and gut bacteria
This study collects stool samples from healthy adults to see how dairy phages and antibiotics affect gut bacteria. It helps researchers understand how our diet and medicines interact with the microbiome.
Jouy-en-JosasAges 18–60 - NCT06929364Recruiting
Probiotics for endometriosis – a crossover trial
This study tests whether taking a probiotic supplement can help with endometriosis symptoms. It's for women 35 or younger with moderate to severe endometriosis, and involves a crossover design where everyone gets both the probiotic and a placebo at different times.
ZagrebAges Up to 35 years - NCT07194551Recruiting
Checking uterine cancer risk in Lynch syndrome with home sampling
This study is testing a new way to check for uterine cancer risk in people with Lynch syndrome. You would collect a vaginal sample yourself at home and fill out a health questionnaire, which may help catch warning signs early.
Vancouver, British ColumbiaAges 30 years+ - NCT07195006Recruiting
Malnutrition in pregnancy and child growth study
This study looks at how nutrition during pregnancy affects the health of mothers and babies, including gut health and growth. It compares women with low nutrition to those with healthy nutrition.
HarareAges 18 years+ - NCT07186465RecruitingPhase 4
Preventing repeat bladder infections in postmenopausal women
This trial tests two approaches to prevent repeat bladder infections in postmenopausal women: a daily antibiotic pill or a vaginal tablet containing healthy bacteria and estrogen. The goal is to see which method works better over 6 months.
Bangkok, Phayatai RatchathewiAges 40 years+ - NCT07189390RecruitingPhase 2
Probiotic study for infants who had antibiotics at birth
This study tests whether giving a probiotic (a 'good' bacteria) to babies who received antibiotics shortly after birth can help their developing gut and immune system. Participants will receive a daily probiotic or placebo for about 6 weeks, and their health will be monitored.
Adelaide, South AustraliaAges Up to 4 weeks - NCT07169019RecruitingEarly Phase 1
Probiotics and methotrexate for early psoriasis
This pilot study tests whether adding probiotics to standard methotrexate treatment improves symptoms in people newly diagnosed with chronic plaque psoriasis. It aims to see how the gut microbiome affects treatment response.
AlexandriaAges 18 years+ - NCT07173062Recruiting
Algae supplement for heart health and gut bacteria
This study tests whether a supplement made from algae can help improve markers of heart health and affect the bacteria in your gut. It is for people age 50 and older who already have a condition like heart disease, kidney disease, or diabetes.
PortoAges 50 years+ - NCT07162337Recruiting
Diet education to lower colon cancer risk after polyp removal
This study tests whether a diet education program can change the balance of gut bacteria and bile acids to lower the risk of colorectal cancer in people who have had polyps removed.
Boston, MassachusettsAges 18–80 - NCT06921746Recruiting
Urinary microbiome and metabolism changes in overactive bladder treatment
This study looks at how the bacteria and chemicals in your urine change when women receive treatment for overactive bladder. It may help researchers understand why some treatments work better for some people.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT07144826RecruitingEarly Phase 1
Probiotic for Gut and Vaginal Health in Ovarian Cancer Chemotherapy
This trial tests whether taking a probiotic supplement can help balance the bacteria in your gut and vagina while you undergo chemotherapy for advanced ovarian cancer. It aims to see if this could improve your treatment experience or outcomes.
Columbus, OhioAges 18 years+ - NCT07143981Recruiting
Fecal transplant for anorexia nervosa
This trial tests whether taking fecal microbiome transplant (FMT) capsules can help people with anorexia nervosa. FMT uses processed stool from healthy donors to improve gut bacteria, which might support weight restoration and overall health.
London, OntarioAges 16–35 - NCT07129174Recruiting
Lung bacteria changes in neurosurgery ICU patients with breathing tubes
This study looks at how tiny organisms in the lungs (the lung microbiome) change in neurosurgery patients who need a breathing tube in the ICU. It aims to see if these changes affect recovery or outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06342752Recruiting
Breath test for early lung disease in premature babies
This trial studies a breath test to predict lung disease in very premature babies. It could help doctors start treatment earlier to prevent serious breathing problems.
Edegem, AntwerpAges birth–3 days - NCT07111455Recruiting
Oral bacteria changes with chemoimmunotherapy for mouth cancer
This study is testing whether a combination of chemotherapy and immunotherapy before surgery can help treat advanced oral cancer. Researchers will also look at how the cancer changes the bacteria in your mouth.
Guangzhou, GuangdongAges 18–80 - NCT07093463Recruiting
Colon-delivered Vitamin B2 for Gut Health
This trial tests whether a special form of vitamin B2 (riboflavin) delivered to the colon can improve gut health in people with mild to moderate bowel complaints. The study compares the effects of this supplement to a standard diet add-on (inulin) and looks at changes in gut bacteria and symptoms.
Berlin, State of BerlinAges 50–70 - NCT07093346Recruiting
Pectin supplement for fatty liver disease
This study tests whether a pectin supplement (a fiber found in fruits) can reduce inflammation and improve liver and metabolic health in people with fatty liver disease (MASLD). You might be eligible if you have MASLD, a healthy weight range, and can avoid certain medications and foods.
Nottingham, United KingdomAges 18 years+ - NCT06959043Recruiting
Diet and exercise for type 2 diabetes
This study tests if a plant-based diet and exercise program can improve blood sugar control in people with type 2 diabetes. Participants will live in a hospital for 4 weeks to follow the program closely.
São Paulo, São PauloAges 45–70
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Common questions
- Are there clinical trials for microbiome?
- Yes. Clin2 currently lists 346 recruiting microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.