Clinical trials
Mild Cognitive Disorder clinical trials
Below are recruiting mild cognitive disorder clinical trials, each written for real people, not researchers. We’re tracking 308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06088121Recruiting
TMS with cognitive training for mild Alzheimer's dementia
This study tests a combination of brain stimulation (TMS) and cognitive training to improve memory and thinking in people with mild Alzheimer's. It may help if you are already on a stable dose of a donepezil-type medication and have a confirmed Alzheimer's diagnosis.
Incheon, Bupyeong 6(yuk)-dong, Bupyeong-guAges 60–85 - NCT07218471Recruiting
Cannabis reduction study for heavy users
This study tests if helping people reduce heavy cannabis use improves daily life. It's for adults with cannabis use disorder who want to cut back.
Charleston, South CarolinaAges 18 years+ - NCT05649514Recruiting
Studying sleep problems in early Alzheimer’s risk patients
This study looks at sleep problems in people with mild Alzheimer’s disease and whether sleep measurements and questionnaires can help researchers understand early changes. You may be able to join if your diagnosis is mild and you can complete repeated sleep and thinking questionnaires with a family caregiver’s help.
Montpellier, HéraultAges 50–85 - NCT05895513RecruitingPhase 2
Pimavanserin trial for aggression and social thinking
This Phase 2 trial tests pimavanserin, a medication that may affect brain signals, to see if it can reduce aggression and improve social thinking in people with intermittent explosive disorder (IED) or a history of aggressive behavior. If you qualify, you’ll be screened with medical tests and questionnaires and must meet medication and safety rules to participate.
Columbus, OhioAges 21–55 - NCT06030154Recruiting
Boosting positive feelings for people with alcohol use disorder
This study tests a program designed to help people with alcohol use disorder who also struggle with low mood or anxiety. It aims to increase positive emotions, which may make it easier to reduce drinking.
Tulsa, OklahomaAges 18–65 - NCT06375213Recruiting
Memory and thinking study for all ages
This study looks at how well people think and remember as they age. It includes healthy volunteers, people with mild memory issues, and those with dementia—both early- and late-onset.
Pathum Wan, BangkokAges 35 years+ - NCT07025317Recruiting
Study on concussions and brain training in older adults
This study looks at how repeated concussions affect the brain as we age. It tests a computer-based brain training program and uses MRI scans to see if training can help improve thinking and memory.
Victoria, British ColumbiaAges 60 years+ - NCT07532551Recruiting
Online Therapy for Anxiety and Depression in Singapore
This study tests an internet-based cognitive behavioral therapy (a self-guided online mental health program) for people with mild-to-moderate anxiety or depression. You'd use an app on your phone or computer to work through lessons and exercises designed to help manage these feelings.
SingaporeAges 21 years+ - NCT07033468Recruiting
Virtual reality cognitive training for mild to moderate dementia
This study tests whether using a full-immersive virtual reality program can help improve thinking and memory skills in people with mild or moderate dementia. It aims to see if this type of training is both possible and helpful.
New Taipei CityAges 55 years+ - NCT05851950Recruiting
Group CBT to reduce rumination in psychosis
This trial tests a structured group therapy (rumination-focused CBT) to help reduce repetitive negative thinking (“rumination”) that can worsen symptoms in people with psychosis. It may help you feel less stuck in unhelpful thoughts and improve day-to-day functioning while you continue your usual care.
CopenhagenAges 18–37 - NCT06416514Recruiting
Personalized help for mild behavioral changes
This study tests a personalized program to support people with mild behavioral impairment (changes in mood, motivation or social behavior) and see if it can improve their health. If you are 60 or older and notice these changes, this trial might help you get tailored support.
Fuzhou, FujianAges 60 years+ - NCT05875103Recruiting
Brain and language study using a word fluency task
This study looks at how thinking and language work in people with certain brain conditions, using a simple word-finding task and brain scans. It may help researchers better understand what brain changes are linked to different symptoms.
AmiensAges 18 years+ - NCT06112639Recruiting
Dance-based rehab for chronic brain conditions
This trial tests a dance exercise program for people with multiple sclerosis or early memory loss. It aims to see if dancing can help physical and mental function safely at home.
BresciaAges 18–85 - NCT06150196Recruiting
Brain health classes for veterans with TBI
This trial tests whether brain health and wellness classes can help veterans who have had multiple mild traumatic brain injuries and also have PTSD. The classes aim to improve cognitive symptoms like memory and attention.
Martinez, CaliforniaAges 18–75 - NCT07625241Recruiting
Brain and Movement Training for Mild-to-Moderate Dementia
This study tests two types of training—cognitive (brain) and movement exercises—for people with mild-to-moderate dementia. The goal is to see if these activities together can help improve thinking, memory, and physical function.
Genova, GenovaAges 65 years+ - NCT07229521Recruiting
Nattokinase for heart, gut, sleep, and brain health in metabolic syndrome with sleep issues
This study tests whether a supplement called nattokinase can improve heart health, sleep, thinking, and gut bacteria in people with metabolic syndrome and mild-to-moderate sleep apnea. If you have a larger waist, blood pressure or blood sugar issues, or imbalanced cholesterol, and have been diagnosed with mild or moderate sleep apnea, you may be eligible.
TaipeiAges 18 years+ - NCT06859996Recruiting
Cognitive rehab study for memory and focus after mild brain injury
This study tests two different types of cognitive rehabilitation (education and problem-solving strategies) delivered via video appointments. It may help people with ongoing thinking and memory problems after a mild brain injury.
Seattle, WashingtonAges 18 years+ - NCT05435222Recruiting
Male-only therapy program for major depression
This study tests a counseling/psychotherapy program designed specifically for men with major depression. If you qualify, you may be offered this structured therapy and followed to see whether it helps depressive symptoms.
Zurich, Canton of ZurichAges 25–50 - NCT05726045Recruiting
Sleep-based brain training to help you quit smoking
This study tests a way to improve smoking cessation using special sleep-based brain stimulation and memory support. If it works, it may help you stay committed to quitting by strengthening helpful brain learning during sleep.
Mannheim, Baden-WurttembergAges 18–65 - NCT07246993Recruiting
Brain training for ongoing symptoms after concussion
This trial tests if a gentle brain stimulation technique called tDCS can help people with persistent memory or thinking problems after a mild concussion. You will use a smartphone app and may receive active or placebo stimulation over several sessions.
Minneapolis, MinnesotaAges 18–65 - NCT07349706Recruiting
Breathing exercise for dementia risk reduction
This trial tests a simple breathing exercise done for about 5–10 minutes each day for 8 weeks. It aims to see if this exercise can reduce your risk of dementia. If you are between 60 and 80 years old and have at least one risk factor for dementia, this study may be a fit for you.
Tallahassee, FloridaAges 60–80 - NCT07071350RecruitingPhase 2/Phase 3
Optimizing heart rate for persistent concussion symptoms in military veterans
This trial tests a treatment designed to improve heart rate variability, which may help reduce long-term concussion symptoms like headaches, dizziness, and trouble sleeping. It is for military veterans who have had a mild concussion more than a year ago and still have ongoing symptoms.
Richmond, VirginiaAges 18 years+ - NCT03819608Recruiting
Brain stimulation and rehab after mild concussion with PTSD or cognitive issues
This trial studies whether brain stimulation plus targeted brain rehabilitation can improve symptoms after a mild concussion (mTBI). You may be invited if your concussion happened at least 3 months ago and your symptoms are affecting thinking or mood, with or without PTSD.
Chicago, IllinoisAges 18–80 - NCT07430800Recruiting
AI-Powered CBT for Anxiety in University Students
This study tests whether personalized computer models can improve cognitive behavioral therapy (a talk therapy that helps change thinking patterns) for anxiety. It's for university students who have mild to moderate anxiety and are comfortable with being recorded during sessions.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for mild cognitive disorder?
- Yes. Clin2 currently lists 308 recruiting mild cognitive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mild Cognitive Impairment
- Amnestic Mild Cognitive Impairment
- Cognitive Dysfunction, Cognitive Disorder
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Amnestic Mild Cognitive Disorder
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.