Clinical trials
Mild Cognitive Disorder clinical trials
Below are recruiting mild cognitive disorder clinical trials, each written for real people, not researchers. We’re tracking 303 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05375513Recruiting
Home exercise and brain-health support for mild memory trouble
This study tests a program you do at home (with online coaching) to help people with mild memory problems (“mild cognitive impairment”) improve thinking and brain health. It also focuses on lowering extra risk factors (like low activity, poor sleep, diet, or heart/metabolic risks).
Edmonton, AlbertaAges 60–85 - NCT05591027RecruitingPhase 1
Testing Centella asiatica for memory problems in older adults
This Phase 1 study tests whether Centella asiatica (a plant-based supplement) is safe and reaches its intended target in people with mild cognitive impairment or early Alzheimer’s disease. It also checks how it affects memory-related brain measures like MRI scans, which is why multiple scans are required.
Portland, OregonAges 60–85 - NCT05907343Recruiting
Closed-loop brain stimulation for memory changes
This study tests a type of brain stimulation that adjusts based on your brain signals to see if it can help with cognitive decline or mild memory problems. You may be able to join if you are cognitively normal, or if you have mild cognitive impairment (MCI), and your brain imaging and stimulation setup is possible.
Austin, TexasAges 18–90 - NCT06121544Recruiting
Pre-Alzheimer's Study: Find Early Brain Changes
This study is looking for healthy volunteers to help detect the very earliest signs of Alzheimer's disease—before memory loss starts. You will have tests like memory checks, blood draws, brain scans, and a spinal tap to look for Alzheimer's-related changes.
MalmöAges 50–80 - NCT06444841Recruiting
Memory aids for mild memory loss
This study tests whether using a paper-based or smartphone-based memory support system helps people with mild memory problems remember daily tasks. You and a family member or friend will both participate.
Austin, TexasAges 50 years+ - NCT06579378Recruiting
Virtual reality sailing for memory and thinking
This study tests whether a virtual reality sailing program called 'VSail 3D' can help improve thinking and memory in older adults with mild cognitive impairment. It looks at whether the program is easy and safe to use.
Cagliari, CAAges 65 years+ - NCT07002996Recruiting
Virtual reality memory training for mild cognitive impairment
This study tests whether a special memory training program using virtual reality can improve thinking skills in people with mild cognitive impairment. It may help slow memory loss and keep your mind sharper.
Verdun, QuebecAges 55 years+ - NCT07064226Recruiting
Digital cognitive rehab for older adults
This trial tests a digital program designed to help improve cognitive skills in older adults with mild memory or thinking problems. The program may help strengthen attention, memory, and problem-solving abilities.
MilanAges 65 years+ - NCT07083154RecruitingPhase 3
Testing a dual-action drug for diabetes and early memory loss
This study tests if a new type of diabetes drug that targets two natural hormones can help people with type 2 diabetes who also have early memory problems. If you have type 2 diabetes and mild cognitive impairment or mild dementia, this trial may offer a potential treatment option.
Changsha, HunanAges 50–75 - NCT06335836Recruiting
Social connections and brain health in memory decline
This study looks at how being socially isolated or socially active affects memory and brain health in people who feel their thinking is getting worse. You may join if you notice a slow decline in memory or thinking, but otherwise have normal test results.
Nanjing, China, JiangsuAges 45–85 - NCT06793735Recruiting
Virtual reality app for memory and thinking problems
This trial tests a virtual reality app you can use at home to help with early memory or thinking problems. It may be an option if you have mild cognitive impairment or notice your thinking is slowing down.
Messina, ItalyAges 40–80 - NCT05770479Enrolling by invitation
Testing long-lasting cognitive training for older veterans
This study looks at whether a cognitive training program you’ve already completed can keep helping over time, and whether it can be improved with “booster” sessions. It may help older veterans maintain thinking and daily functioning skills after earlier training.
San Diego, CaliforniaAges 55 years+ - NCT07733726Enrolling by invitation
Dual-Task Mouth and Memory Training for Oral Frailty
This study tests a program that combines mouth exercises with memory tasks to see if it can improve both chewing, swallowing, and thinking skills in people who have oral frailty and some memory decline.
KowloonAges 50 years+ - NCT07643363Recruiting
Brain Stimulation for Cognitive Impairment in Dementia
This study tests a new brain stimulation technique called temporal interference stimulation to help slow cognitive decline in people with Alzheimer's disease or frontotemporal dementia. Researchers will combine this stimulation with cognitive training to see if it improves memory and thinking skills.
Tianjin, Tianjin MunicipalityAges 45–85 - NCT03025334Recruiting
Brain stimulation study for thinking changes in Parkinson’s
This study tests whether a non-invasive brain stimulation approach (tDCS) can improve thinking and memory in people with Parkinson’s disease. You may be invited because your Parkinson’s is typical and your memory testing shows you do not have dementia.
Winnipeg, ManitobaAges 40 years+ - NCT06120361Recruiting
Primary care study for early cognitive decline
This research study looks at people who have noticed problems with memory or thinking (like trouble focusing or finding words) and visit their primary care doctor for help. It aims to better understand and diagnose conditions that cause these symptoms, such as Alzheimer's disease.
MalmöAges 40 years+ - NCT06867692Recruiting
Aerobic exercise for kids with mild cognitive impairment
This trial tests if aerobic exercise helps kids with mild cognitive impairment do better at two tasks at once and improve their motor skills. It could help your child think and move more easily.
Lahore, Punjab ProvinceAges 7–12 - NCT07424365Recruiting
Vagus nerve stimulation for thinking skills in health and Parkinson's
This study explores whether vagus nerve stimulation (a gentle electrical pulse that travels through a nerve in your ear) can boost thinking and decision-making skills in healthy people and those with Parkinson's disease. It involves a noninvasive device that stimulates the ear, and you may participate if you meet certain health criteria.
Aurora, ColoradoAges 18–65 - NCT06973018Enrolling by invitation
Online cognitive rehab for mild memory problems
This trial tests an online program to help people with mild to moderate cognitive problems after a brain injury or nervous system disease improve their thinking skills. It is for Swedish speakers with internet access.
Stockholm, Stockholm CountyAges 18 years+ - NCT06927362Recruiting
Exercise and balance training for seniors with memory issues
This study tests if combining two types of exercise (LSVT Big and dual-task training) can improve balance and thinking in older adults with mild to moderate memory loss. It may help you stay steady on your feet and manage everyday tasks more easily.
Lahore, Punjab ProvinceAges 65 years+ - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06181513RecruitingEarly Phase 1
Probiotics for mild Alzheimer's disease
This study tests whether daily probiotics (beneficial bacteria) can help people with mild Alzheimer's disease. It's an early-phase trial to see if probiotics are safe and might improve thinking and memory.
NicosiaAges 65–85 - NCT07309302Recruiting
Online brain training for PTSD: a remote study
This study tests whether online cognitive training can help people with PTSD. It is fully remote and requires a computer with a camera.
Montreal, QuebecAges 18–45 - NCT03020381Recruiting
Study of walking patterns to predict dementia and falls
This study looks at how your walking (gait) might help predict future dementia and risk of falls. You may be asked to walk tests and have health information collected to see who is at higher risk.
London, OntarioAges 60–85
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Common questions
- Are there clinical trials for mild cognitive disorder?
- Yes. Clin2 currently lists 303 recruiting mild cognitive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mild Cognitive Impairment
- Amnestic Mild Cognitive Impairment
- Cognitive Dysfunction, Cognitive Disorder
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Amnestic Mild Cognitive Disorder
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.