Clinical trials
Mild Cognitive Disorder clinical trials
Below are recruiting mild cognitive disorder clinical trials, each written for real people, not researchers. We’re tracking 312 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06832605Recruiting
Mindfulness classes by video to prevent depression relapse
This trial tests an 8-week mindfulness-based cognitive therapy program delivered via video call to help people with a history of depression prevent future episodes. It may help you learn skills to manage low mood and reduce the chance of relapse.
Elche, AlicanteAges 18 years+ - NCT07511270Recruiting
Predicting thinking skills from speech using AI
This study uses an AI tool to analyze short stories you tell aloud, to see if it can predict your thinking and memory test scores. It may help develop a simpler way to check cognitive health.
TaoyuanAges 50 years+ - NCT05594017RecruitingEarly Phase 1
Test medicine to change brain rhythms and study memory
This early research study tests whether a medicine can change the brain’s electrical “rhythms” while people do memory-related tasks. It may help researchers understand how brain timing affects memory in people who are already being evaluated with specialized brain electrode monitoring.
Dallas, TexasAges 18–55 - NCT05457725Recruiting
Study how aging affects learning to trust and distrust
This study looks at how thinking and learning processes change with age, especially around deciding what to trust. You may be asked to complete computer tasks and brief memory/thinking tests to understand these changes.
Gainesville, FloridaAges 18–100 - NCT07083154RecruitingPhase 3
Mazdutide for type 2 diabetes with early memory problems
This study tests a new medication, Mazdutide, to see if it can slow or improve memory and thinking problems in people with type 2 diabetes and early-stage cognitive impairment. It may help by targeting blood sugar control and possibly reducing the impact of diabetes on brain function.
Changsha, HunanAges 50–75 - NCT07372066Recruiting
Brain exercise group for seniors with memory concerns
This trial tests a cognitive stimulation therapy group for older adults living in residential homes who have mild cognitive impairment or dementia. The goal is to see if group activities can help keep the mind active and improve quality of life.
Hong Kong, Hong KongAges 60 years+ - NCT07304674Recruiting
Primary Aldosteronism and Thinking Ability Study
This study looks at whether primary aldosteronism (a treatable cause of high blood pressure) is linked to memory and thinking problems. It may help understand if managing this condition can protect brain health.
Chengdu, SichuanAges 40 years+ - NCT03702907Recruiting
Study of aging and a brain sample bank
This study follows adults as they age and may collect biological samples for future research. It could help researchers understand early and late changes related to aging and brain health.
Washington D.C., District of ColumbiaAges 45 years+ - NCT05924425RecruitingPhase 4
Daridorexant for insomnia in early memory decline
This trial tests whether daridorexant can improve sleep in people who have mild cognitive impairment or early Alzheimer’s disease and struggle with insomnia. It may help by improving how long and how well you sleep, with monitoring of sleep patterns and memory-related measures.
MontpellierAges 60–85 - NCT05079464Recruiting
Exercise plus brain stimulation to improve memory in early impairment
This trial tests whether a supervised exercise program, paired with brain stimulation, can improve thinking and memory in people with early “vascular” cognitive problems (not dementia). It may help your brain function before memory loss becomes more severe.
Toronto, OntarioAges 50 years+ - NCT07287527Recruiting
Light therapy for memory and brain health
This study tests whether a type of light therapy called photobiomodulation can improve brain connections and thinking abilities in people with mild memory problems.
IstanbulAges 55 years+ - NCT04123314RecruitingEarly Phase 1
Psilocybin study for depression in mild memory or early Alzheimer’s
This early-phase study tests whether psilocybin (a psychedelic substance) can help with depression in people who have mild memory problems or early Alzheimer’s. The trial also closely monitors safety, thinking changes, mood, and blood pressure before and after dosing.
Baltimore, MarylandAges 18–85 - NCT07000500Enrolling by invitation
Nutritional supplement for memory decline in older adults
This trial tests whether a nutritional supplement can help slow or improve memory loss in older adults who have mild cognitive decline (noticeable changes in thinking skills that are not yet dementia). You will take a daily supplement and attend regular check-ups.
Vila Nova de Famalicão, Braga DistrictAges 65 years+ - NCT07130669RecruitingPhase 1/Phase 2
Memory and thinking study for older adults
This trial tests a program to help maintain or improve memory and thinking skills in older adults. You may join if you are 60-89, speak English, and live at home or in an assisted-living facility.
Palo Alto, CaliforniaAges 60–89 - NCT07338682RecruitingPhase 2
L-Arginine for memory in older adults
This trial tests if L-Arginine, a natural amino acid, can improve thinking and memory in adults over 60 with mild to moderate memory problems. You may join if you have no other brain diseases or certain health conditions.
CairoAges 60 years+ - NCT07289061Recruiting
Positive psychology for early memory changes
This trial tests whether positive psychology exercises can help improve memory and brain function in people with very early memory changes. It may be a good fit if you have noticed new memory concerns or a mild cognitive impairment.
ThessalonikiAges Any age - NCT06964581Recruiting
At-home cognitive training for multiple sclerosis
This study tests a at-home thinking and memory training program for people with multiple sclerosis. It aims to help improve mental skills like memory, attention, and planning through remote sessions.
Verona, veronaAges 18–65 - NCT07377682Recruiting
Trazodone for depression with mild memory problems
This study tests how well the antidepressant trazodone works in older adults with major depression and mild cognitive impairment (early memory or thinking problems). It looks at real-world results in people starting this treatment.
Lodz, PolandAges 55 years+ - NCT07146373Recruiting
Breathing muscle training and thinking ability study
This trial tests whether training the muscles you use to breathe in can help improve thinking and memory. It's for people with mild to moderate cognitive changes who are on stable medication.
Aigáleo, AtticaAges 60–90 - NCT06871384Recruiting
Red wine diet for brain and body health in early elderly
This study tests whether a special diet including red wine can help improve thinking and movement in people aged 60–74. If you join, you would drink red wine as part of the diet and have your memory and physical abilities checked over time.
Logroño, SpainAges 60–74 - NCT06597591Recruiting
Virtual reality training to improve self-control in memory loss patients
This study tests whether a virtual reality training game can help improve your ability to stop yourself or control impulses, which can be affected in early memory problems. You will use a VR headset to practice these skills in a safe, fun environment.
NiceAges 60 years+ - NCT06268080Recruiting
Sedation depth and mental recovery after surgery for older adults
This trial tests whether monitoring how deeply you sleep during anesthesia helps prevent confusion and memory problems after surgery. It is for older adults who can give consent and are having a major operation.
Grafton, AucklandAges 55 years+ - NCT07717567Recruiting
Blood tests to diagnose and predict Alzheimer's disease
This study is testing whether a simple blood test can help diagnose Alzheimer's disease and predict how the disease will progress. If you have memory or thinking problems that have been getting worse, you may be able to join.
Milan, MilanoAges 40 years+ - NCT04184375Recruiting
Memory training for older adults with bipolar disorder
This study tests whether structured memory and thinking exercises (cognitive stimulation) help older adults with bipolar disorder who have mild to moderate thinking and memory problems. You may be offered guided sessions designed to improve everyday thinking skills while checking safety and fit for the program.
La RochelleAges 65 years+
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Common questions
- Are there clinical trials for mild cognitive disorder?
- Yes. Clin2 currently lists 312 recruiting mild cognitive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mild Cognitive Impairment
- Amnestic Mild Cognitive Impairment
- Cognitive Dysfunction, Cognitive Disorder
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Amnestic Mild Cognitive Disorder
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.