Clinical trials
Mitral Valve Regurgitation clinical trials
Below are recruiting mitral valve regurgitation clinical trials, each written for real people, not researchers. We’re tracking 115 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04688190Recruiting
Registry study for choosing a mitral valve treatment
This study collects and compares real-world results to help doctors choose the best treatment for mitral valve “leakiness.” If you have clinically significant mitral insufficiency and have already had a specific heart procedure screening, your echocardiogram results may be used to understand outcomes over at least a month.
Tucson, ArizonaAges 18 years+ - NCT04775108Recruiting
Testing a new heart procedure for severe leaking mitral valve
This trial studies a new transcatheter (through the heart without open surgery) mitral valve treatment for people with severe mitral valve leaking who are too high-risk for standard surgery. It may help reduce valve leakage and improve symptoms, but it’s an early “first-in-human” device study.
InnsbruckAges 60 years+ - NCT04888247Recruiting
Testing a new mitral valve replacement for high-risk patients
This study checks whether an innovative device can safely replace a damaged mitral valve in people who are higher risk for open-heart surgery. It looks at how well the procedure and follow-up work for improving mitral leakage symptoms.
AuchenflowerAges 18 years+ - NCT04898335Recruiting
Tendyne heart valve registry for real-world patient experiences
This registry collects information from people who received the Tendyne mitral valve in routine care. It helps doctors understand how the valve performs in everyday practice and may guide future care.
LinzAges 18 years+ - NCT04913727Recruiting
Testing heart scan predictions after mitral valve repair
This trial studies severe secondary mitral valve leaking and uses heart imaging to predict how well the heart and symptoms improve after a less-invasive valve procedure. It may help doctors better forecast who benefits most from this repair.
BernAges 18 years+ - NCT05021614Recruiting
Valveclip repair study for leaking mitral valve in older adults
This trial tests Valveclip, a catheter-based way to repair a mitral valve that is leaking badly. It may help people who are high-risk for open surgery by aiming to reduce the leak with a less invasive approach.
SichuanAges 60 years+ - NCT05061004Recruiting
Testing a new mitral valve treatment delivered through a catheter
This trial tests a new mitral valve device that may improve blood flow in people with significant mitral valve leakage or narrowing, using a catheter instead of open-heart surgery. It’s meant for patients who doctors think this catheter approach is a better fit than surgery.
Phoenix, ArizonaAges 18 years+ - NCT05455489Recruiting
MitraClip registry for severe mitral valve leakage patients
This registry study collects information on people with severe mitral valve leakage (regurgitation) who are treated with the MitraClip G4 device. It aims to better understand which patients benefit most and how well the procedure works in real-world care.
San Donato Milanese, MilanoAges 18 years+ - NCT05496998Recruiting
Heart valve replacement using a catheter for leaking mitral valve
This trial studies a catheter-based procedure to replace the mitral valve in people with severe (or specific moderate) mitral valve leakage that causes symptoms. It may help by reducing leaking and related symptoms when standard surgery or less invasive fixes aren’t suitable for you.
AarhusAges 18 years+ - NCT05610566Recruiting
HighLife valve replacement for severe leaking mitral valve
This trial studies a new catheter-based valve replacement system for people with moderate to severe, or severe, mitral valve regurgitation (a leaky mitral valve). It aims to check whether the procedure is safe and can improve heart function compared with expected care.
Suzhou, JiangsuAges 18 years+ - NCT05655897Recruiting
Clips for leaky mitral valve in high-surgery-risk heart patients
This trial studies whether a device called GeminiOne can safely and effectively repair a leaky mitral valve using a catheter-based “clip” technique. It may help patients who have moderate-to-severe or severe valve leakage but are considered too high-risk for open surgery.
Suzhou, JiangsuAges 18 years+ - NCT05920824Recruiting
Testing treatment for leaking mitral and tricuspid valves
This trial studies people with atrial fibrillation and moderate-to-severe leakiness in the mitral and tricuspid valves in the heart. It likely aims to improve symptoms and heart function by better addressing how these valve leaks happen.
LondonAges 18 years+ - NCT06235385Recruiting
European study on multiple and mixed valve disease
This study looks at people with multiple or mixed heart valve disease (moderate or severe) using echocardiography. It aims to learn more about how these conditions affect patients and help guide future care.
Paris, Île-de-France RegionAges 18 years+ - NCT06255457Recruiting
Heart rhythm study for patients getting mitral valve surgery
This study looks at heart rhythm problems in people having mitral valve surgery to fix a leaky valve. It may help doctors better understand who is at risk for dangerous rhythms.
Stockholm, Stockholm CountyAges 18 years+ - NCT06414265Recruiting
Testing a new valve for severe mitral regurgitation
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
TbilisiAges 65 years+ - NCT06552689Recruiting
Testing Sutra Hemi-valve for leaky mitral valve
This trial tests a new, less invasive heart valve (Sutra Hemi-valve) for people with a leaky mitral valve who cannot have standard surgery. The valve is delivered through a vein in your leg, so you avoid open-heart surgery.
HamiltonAges 18 years+ - NCT06634121Recruiting
Comparing MitraClip and PASCAL for mitral valve repair
This trial compares two devices (MitraClip and PASCAL) for repairing a leaky mitral valve (mitral regurgitation). The goal is to see which device works better in a wide range of patients who need this type of repair.
Munich, BavariaAges 18 years+ - NCT07243184Recruiting
Polymer heart valve study for mitral valve disease
This trial is testing a new polymer artificial heart valve for people with severe mitral valve problems. It aims to see if this valve is safe and works well during surgical replacement.
BeijingAges 60 years+ - NCT06805253Recruiting
Heart recovery after surgery for leaky aortic valve
This trial studies how well the heart's main pumping chamber (left ventricle) recovers after surgery to fix a leaky aortic valve. It is for people who also have a leaky mitral valve and an enlarged left ventricle, and who are having their first planned valve surgery.
MoscowAges 18 years+ - NCT06917586Recruiting
Mosaic mitral valve study for patients under 65
This study looks at long-term results in people under 65 who received a specific type of replacement heart valve (the Mosaic mitral valve) during surgery at ProMedica Toledo Hospital. It aims to understand how well the valve works over time.
Toledo, OhioAges 18–65 - NCT07069673Recruiting
Abbott Cephea mitral valve disease registry
This study tracks people with mitral valve disease who receive the Cephea valve through a tube in an artery rather than open-heart surgery. It looks at how well the valve works over time.
Birmingham, AlabamaAges 18 years+ - NCT07097740Recruiting
Study of a new polymer heart valve for mitral or aortic replacement
This study tests a new type of prosthetic heart valve made from a special polymer material. It is for adults who need surgical replacement of either the mitral or aortic valve.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT07188233Recruiting
Catheter repair for leaky mitral valve in heart failure
This trial tests a new device (CathHELIX) placed through a vein to repair a leaky mitral valve in people with heart failure. It is for people with moderate to severe mitral regurgitation who still have symptoms despite medical therapy.
Tbilisi, GeorgiaAges 18 years+ - NCT07244939Recruiting
Testing a new heart valve device for leaky valves
This study tests the Cephea valve, a less invasive option for people with severe mitral valve leakage or narrowing who are not good candidates for open-heart surgery. It checks if the device can safely improve valve function.
São PauloAges 18 years+
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Common questions
- Are there clinical trials for mitral valve regurgitation?
- Yes. Clin2 currently lists 115 recruiting mitral valve regurgitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mitral valve regurgitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mitral valve regurgitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.