Clinical trials
Mitral Valve Regurgitation clinical trials
Below are recruiting mitral valve regurgitation clinical trials, each written for real people, not researchers. We’re tracking 113 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07470788Recruiting
Vesalius TMVr system for leaky heart valve (mitral regurgitation)
This study tests a new device called the Vesalius TMVr system to fix a leaky mitral valve without open-heart surgery. It's for people with severe mitral regurgitation who are not good candidates for surgery.
VancouverAges 19 years+ - NCT07450911RecruitingPhase 1
Mitral valve replacement with the ReValve system
This study is for people with severe mitral valve leakage (mitral regurgitation) who may need a valve replacement. It tests whether the ReValve system is safe and can help improve symptoms and heart function.
TbilisiAges 18 years+ - NCT06823700Recruiting
Study of SQ-Kyrin device for leaky mitral valve from heart failure
This trial tests a new device (SQ-Kyrin) to fix a leaky mitral valve without open-heart surgery. It is for people with heart failure whose valve leak causes symptoms, and who are not good candidates for traditional surgery.
Valladolid, ValladolidAges 18 years+ - NCT04195984Recruiting
Heart valve replacement through a catheter for leaky mitral valve
This trial studies a new way to replace a damaged mitral heart valve using a catheter (a thin tube), instead of open-heart surgery. It may help people who have severe leaking of the mitral valve but are considered too high-risk for surgery.
Beijing, Beijing MunicipalityAges 65 years+ - NCT04029337Recruiting
Transcatheter mitral valve replacement for severe leakage
This study tests a new device that replaces a leaking mitral valve without open-heart surgery. It may help people who have severe mitral valve leakage but cannot safely have standard surgery or some other less invasive valve repairs.
Tucson, ArizonaAges 18 years+ - NCT06552689Recruiting
Testing Sutra Hemi-valve for leaky mitral valve
This trial tests a new, less invasive heart valve (Sutra Hemi-valve) for people with a leaky mitral valve who cannot have standard surgery. The valve is delivered through a vein in your leg, so you avoid open-heart surgery.
HamiltonAges 18 years+ - NCT07296016Recruiting
Asia-Pacific mitral and tricuspid valve replacement registry
This study collects information from patients in the Asia-Pacific region who have had or plan to have a procedure to replace a failing mitral or tricuspid valve with a new valve placed inside the old one (called valve-in-valve) or inside a ring that was used in a previous repair (valve-in-ring). The goal is to learn more about how well these procedures work and how they can be improved.
Hong Kong, ShatinAges 21 years+ - NCT07267117Recruiting
Heart valve disease progression and outcomes study
This study is following people with heart valve disease (leaky or narrowed valves) to understand how the disease changes over time and what problems it may cause. It does not test a new treatment, but helps doctors learn more about valve disease progression.
Fuzhou, FujianAges 18 years+ - NCT07243184Recruiting
Polymer heart valve study for mitral valve disease
This trial is testing a new polymer artificial heart valve for people with severe mitral valve problems. It aims to see if this valve is safe and works well during surgical replacement.
BeijingAges 60 years+ - NCT07188233Recruiting
Catheter repair for leaky mitral valve in heart failure
This trial tests a new device (CathHELIX) placed through a vein to repair a leaky mitral valve in people with heart failure. It is for people with moderate to severe mitral regurgitation who still have symptoms despite medical therapy.
Tbilisi, GeorgiaAges 18 years+ - NCT07151989Enrolling by invitation
How valve disease type affects new valve durability
This study looks at people who had their mitral valve replaced to see if the original valve problem (tight vs leaky) affects how long the new valve lasts. It may help doctors understand which patients need closer follow-up.
Maastricht, MaastrichtAges 18 years+ - NCT07130994Recruiting
Testing a new less invasive mitral valve replacement (SATURN)
This trial tests a new, less invasive device called the SATURN system to replace a severely leaky mitral heart valve without open-heart surgery. It is for people who are too high-risk for traditional surgery and are willing to take blood thinners.
Los Angeles, CaliforniaAges 18 years+ - NCT07097740Recruiting
Study of a new polymer heart valve for mitral or aortic replacement
This study tests a new type of prosthetic heart valve made from a special polymer material. It is for adults who need surgical replacement of either the mitral or aortic valve.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT07069673Recruiting
Abbott Cephea mitral valve disease registry
This study tracks people with mitral valve disease who receive the Cephea valve through a tube in an artery rather than open-heart surgery. It looks at how well the valve works over time.
Birmingham, AlabamaAges 18 years+ - NCT06805253Recruiting
Heart recovery after surgery for leaky aortic valve
This trial studies how well the heart's main pumping chamber (left ventricle) recovers after surgery to fix a leaky aortic valve. It is for people who also have a leaky mitral valve and an enlarged left ventricle, and who are having their first planned valve surgery.
MoscowAges 18 years+ - NCT06917586Recruiting
Mosaic mitral valve study for patients under 65
This study looks at long-term results in people under 65 who received a specific type of replacement heart valve (the Mosaic mitral valve) during surgery at ProMedica Toledo Hospital. It aims to understand how well the valve works over time.
Toledo, OhioAges 18–65 - NCT06465745Recruiting
AltaValve study for leaky mitral valve
This trial tests a new, less invasive device called the AltaValve to treat a leaky mitral valve. It is for people whose leak is severe enough to cause symptoms, but who cannot have standard surgery or a clip procedure.
Phoenix, ArizonaAges 18 years+ - NCT06467110Enrolling by invitation
Study of SQ-Kyrin TMVr System for leaky mitral valve
This trial tests a new device called the SQ-Kyrin TMVr System to treat severe mitral regurgitation (a leaky heart valve) in people who are not good candidates for traditional open-heart surgery. The goal is to repair the valve without major surgery, using a catheter-based approach.
Shenyang, LiaoningAges 18 years+ - NCT06255457Recruiting
Heart rhythm study for patients getting mitral valve surgery
This study looks at heart rhythm problems in people having mitral valve surgery to fix a leaky valve. It may help doctors better understand who is at risk for dangerous rhythms.
Stockholm, Stockholm CountyAges 18 years+ - NCT04029363Recruiting
Transcatheter mitral valve procedure for high-surgery-risk patients
This trial studies a newer, catheter-based mitral valve treatment in people with moderate-severe to severe mitral valve leaking who are at high risk for open-heart surgery. It may help improve symptoms and heart function without traditional surgery, but you must meet key heart, anatomy, and safety requirements.
Darlinghurst, New South WalesAges 18 years+ - NCT06414265Recruiting
Testing a new valve for severe mitral regurgitation
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
TbilisiAges 65 years+ - NCT06282042Recruiting
Early Fix of Leaky Mitral Valve After Heart Attack
This trial tests an early, minimally invasive procedure to fix a leaky mitral valve using a catheter (a thin tube) after a heart attack. The goal is to see if fixing the valve early can help patients recover better and avoid more serious heart problems.
Afula, AfulaAges 18–99 - NCT06113354Recruiting
Testing the MRace implant for leaky heart valve repair
This trial tests a new device called MRace that may fix a leaky mitral valve without open-heart surgery. It's for people whose valve leaks severely and who can't have standard surgery due to other health issues.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT05920824Recruiting
Testing treatment for leaking mitral and tricuspid valves
This trial studies people with atrial fibrillation and moderate-to-severe leakiness in the mitral and tricuspid valves in the heart. It likely aims to improve symptoms and heart function by better addressing how these valve leaks happen.
LondonAges 18 years+
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Common questions
- Are there clinical trials for mitral valve regurgitation?
- Yes. Clin2 currently lists 113 recruiting mitral valve regurgitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mitral valve regurgitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mitral valve regurgitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.