Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,023 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06647979RecruitingPhase 1
Gene editing for severe sickle cell or thalassemia
This trial tests a new gene therapy that edits your own blood stem cells to help them make more fetal hemoglobin, which can prevent sickling and reduce the need for transfusions. It is for people with severe sickle cell disease or beta thalassemia who do not have a matched sibling donor.
Boston, MassachusettsAges 13–40 - NCT06652204Recruiting
Questionnaire for caregivers of COPD patients
This study tests a French questionnaire for caregivers of people with COPD. It aims to better understand caregiver burden and support needs.
BrestAges 18 years+ - NCT05802121RecruitingEarly Phase 1
Testing a gut bacteria supplement side effects during prostate hormone therapy
This early-phase study looks at how changing gut bacteria (especially Akkermansia) affects metabolic side effects in men starting prostate hormone therapy (ADT). It may help researchers understand how to reduce or manage side effects for people on ADT.
London, OntarioAges 18 years+ - NCT06635629RecruitingPhase 2
Desmopressin test for ACTH-dependent Cushing syndrome
This trial studies how well a desmopressin stimulation test works to diagnose ACTH-dependent Cushing syndrome. It compares results from people with possible or recurrent Cushing syndrome and healthy volunteers.
Bethesda, MarylandAges 18–70 - NCT06635681RecruitingPhase 2
Venetoclax plus intensive chemo for AML subtypes
This trial tests whether adding the targeted drug venetoclax to intensive chemotherapy works better for different types of AML. It is for people aged 14 to 60 who are newly diagnosed and have not received prior treatment.
Tianjin, Tianjin MunicipalityAges 14–60 - NCT06639477Recruiting
Mood and sleep improvement study for older adults
This study tests whether adding a sleep treatment to regular depression medication can improve both mood and sleep in adults aged 55 and older. It may help if you have ongoing depression, sleep problems, and are already taking antidepressant medication.
Los Angeles, CaliforniaAges 55 years+ - NCT06632535Recruiting
Group visits and chiropractic care for older adults with chronic spine pain
This study tests whether group medical visits combined with chiropractic care can help older adults with chronic neck or back pain. If you join, you'll receive chiropractic treatments and attend group visits to learn pain management strategies.
Boston, MassachusettsAges 65 years+ - NCT06634004Enrolling by invitation
Using biomarkers to improve surgery outcomes in Moyamoya
This study at Vanderbilt tests whether certain biomarkers (signs in your blood or brain scans) can help tailor care for people with Moyamoya, a condition where blood flow to the brain is reduced. Participants will have brain scans and complete study procedures before and after surgery to improve blood flow.
Baltimore, MarylandAges 18–69 - NCT03549858Recruiting
Survey study on burdens and experiences of people with hemophilia
This study collects information from people with hemophilia about how treatments and daily life affect them. It uses your answers to improve patient-focused care and understand what challenges matter most.
Hamilton, OntarioAges Any age - NCT06630663Recruiting
Wearable device and app for diet and exercise
This trial tests if a wearable device and a smartphone app can help you improve your diet and exercise habits. It is for people who are overweight and have related health conditions like high blood pressure or diabetes.
Taipei, TaipeiAges 20 years+ - NCT06628440Recruiting
Mouth check tool for ICU patients with breathing tubes
This study develops a new tool to check the health of the mouth in patients who have a breathing tube in their throat while in the intensive care unit (ICU). It aims to help nurses better assess and care for the mouth.
AngersAges 18 years+ - NCT06620458Enrolling by invitation
Factors affecting drug-coated balloon restenosis
This study looks at why some drug-coated balloons (used to open blocked heart arteries) might narrow again after treatment. If you have coronary artery disease and are scheduled for this procedure, you may be eligible to help researchers understand what factors affect the balloon's success.
Zhengzhou, ChinaAges 18 years+ - NCT06624358Recruiting
Physical activity study for teens with chronic kidney disease
This study looks at physical activity in teens with chronic kidney disease (CKD) who are not yet on dialysis or have had a transplant. It aims to understand their current activity levels and how to help them stay active safely.
Philadelphia, PennsylvaniaAges 13–18 - NCT06631755Recruiting
How calcium affects stent healing: an imaging study
This study looks at how calcium buildup in artery walls affects how well a stent heals. Doctors will use special imaging (OCT) right after stent placement and again a month later to check the healing of the tiny metal struts.
BarcelonaAges 18 years+ - NCT06624670RecruitingPhase 3
Testing spesolimab for pyoderma gangrenosum skin ulcers
This trial tests whether the drug spesolimab can help people with a skin condition called pyoderma gangrenosum, which causes painful ulcers. It's for adults who have at least one active ulcer that's at least 2 inches across and needs treatment.
Birmingham, AlabamaAges 18 years+ - NCT06623799Recruiting
Allergic rhinitis, help-seeking, and mental health study
This study looks at how people with allergic rhinitis (hay fever) seek help and how that relates to their mental health. Researchers hope to learn more about the connection between allergies, anxiety, and depression over time.
West Palm Beach, FloridaAges 4–100 - NCT05717192Recruiting
Bronchoscopy treatment to shrink severe emphysema using heat
This trial studies a bronchoscopy procedure that uses heat (thermoablation) to reduce over-inflated lung tissue in people with severe emphysema. If you qualify, it aims to improve breathing and walking ability after trying standard treatments first.
BerlinAges 40–75 - NCT06607003RecruitingPhase 1
Testing a malaria infection in healthy adults
This study gives healthy adults who have never had malaria a controlled infection with the parasite that causes malaria, to see if it is safe and if mosquitoes can pick up the parasite from them. It may help develop new ways to prevent malaria.
Bethesda, MarylandAges 18–54 - NCT06615596RecruitingEarly Phase 1
Stopping blood thinners after successful atrial fibrillation ablation
This trial tests whether it is safe to stop taking blood thinners (anticoagulants) after a successful ablation procedure for atrial fibrillation. If you have had no AF for 3 months after your first ablation, you may be able to stop these medications, reducing your risk of bleeding.
Boston, MassachusettsAges 18 years+ - NCT06615609Recruiting
Heart health management after bypass or stent
This trial tests a smartphone-based program to help people manage their blood pressure, blood sugar, and cholesterol after heart procedures like bypass surgery or stenting. It aims to improve long-term heart health.
Ürümqi, XinjiangAges 18 years+ - NCT06607458RecruitingPhase 2
Liver-focused chemo for metastatic colorectal cancer
This trial tests giving high-dose melphalan directly into the liver's blood supply, followed by standard cancer therapy, for people whose colorectal cancer has spread mainly to the liver. The goal is to see if this approach is safer and works better than standard treatment alone.
Duarte, CaliforniaAges 18 years+ - NCT06615843Recruiting
Smartphone app for gynecological follow-up after ER
This trial is testing a new way to manage gynecological follow-up after an emergency visit using a smartphone app instead of in-person visits. It may be a good fit if you had a specific gynecologic condition mentioned above and can use a digital app.
ParisAges 18–60 - NCT06605014Recruiting
Body alignment after stroke or mini-stroke
This study looks at how a stroke or mini-stroke affects the body's natural movement and alignment (called somatic dysfunction). Researchers want to see if there are common patterns of tightness or imbalance after a stroke, which could help guide future treatments.
Sacramento, CaliforniaAges 18 years+ - NCT06611839RecruitingPhase 1/Phase 2
Combination therapy for IDH1-mutated AML
This trial tests a combination of three drugs (venetoclax, ivosidenib, and azacitidine) for people newly diagnosed with a specific type of AML that has an IDH1 mutation. The goal is to see if this mix works better than standard treatments.
Tianjin, Tianjin MunicipalityAges 14 years+
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,023 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.